公开(公告)号：WO2015179725A1

公开(公告)日：2015-11-26

申请号：PCT/US2015/032102

申请日：2015-05-22

Applicant: CASE WESTERN RESERVE UNIVERSITY

Inventor： AHUJA, Punkaj ,  PESHKOVA, Maria A. ,  HEMPHILL, Brian D. ,  GRATZL, Miklós

IPC: G01N21/78 ,  G01N21/80

CPC classification number: G01N21/78 ,  G01N21/80 ,  G01N33/492 ,  G01N33/84 ,  G01N2021/775 ,  G01N2201/064

Abstract: One aspect of the present disclosure relates to an analyte sensor device. The analyte sensor device can include an optode layer that undergoes an optical change in the presence of an analyte. The analyte sensor device can also include a selectively-permeable membrane encapsulating the optode layer to form a stable membrane that that minimizes fouling of the analyte sensor device. The analyte sensor device can also include a plurality of microparticles that suppress a background physical interference on a detection of the optical change of the optode layer.

Abstract translation: 本公开的一个方面涉及分析物传感器装置。 分析物传感器装置可以包括在分析物存在下经历光学变化的光电层。 分析物传感器装置还可以包括封装光栅层的选择性渗透膜，以形成最小化分析物传感器装置结垢的稳定膜。 分析物传感器装置还可以包括多个微粒，其抑制对光栅层的光学变化的检测的背景物理干扰。

公开(公告)号：EP3146317A1

公开(公告)日：2017-03-29

申请号：EP15727789.8

申请日：2015-05-22

Applicant: Case Western Reserve University

Inventor： AHUJA, Punkaj ,  PESHKOVA, Maria A. ,  HEMPHILL, Brian D. ,  GRATZL, Miklós

IPC: G01N21/78 ,  G01N21/80

CPC classification number: G01N21/78 ,  G01N21/80 ,  G01N33/492 ,  G01N33/84 ,  G01N2021/775 ,  G01N2201/064

Abstract: One aspect of the present disclosure relates to an analyte sensor device. The analyte sensor device can include an optode layer that undergoes an optical change in the presence of an analyte. The analyte sensor device can also include a selectively-permeable membrane encapsulating the optode layer to form a stable membrane that that minimizes fouling of the analyte sensor device. The analyte sensor device can also include a plurality of microparticles that suppress a background physical interference on a detection of the optical change of the optode layer.

Abstract translation: 本公开的一个方面涉及在分析物传感器的设备。 分析物传感器装置可包括在光极层并进入下在的存在光学变化的分析物。 因此，该分析物传感器装置可包括选择性渗透膜封装所述光极层，以形成thatthat尽可能缩短结垢分析物传感器装置的稳定膜。 因此，该分析物传感器装置可包括多个微粒确实抑制在检测到所述光极层的光学变化的背景物理干扰。