-
公开(公告)号:CA2050121C
公开(公告)日:2005-04-19
申请号:CA2050121
申请日:1991-08-28
Applicant: CIBA CORNING DIAGNOSTICS CORP
Inventor: CAREY GLEN A , POLANIEC JAMES P , LEWIS SCOTT C , WOYANSKY GEORGE J , MANN RAYMOND A , PABST STEFAN R , WHITESEL MARY BETH , KLINGSHIRN FRANK C
IPC: G01N21/78 , B01L3/00 , G01N21/03 , G01N21/76 , G01N33/53 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , B01L3/14 , G01N21/64
Abstract: An analyzer for performing automated assay testing. The analyzer includ es a storage and conveyor system for conveying cuvettes to an incubation or processing conveyor, a storage and selection system for test sample containers, a stora ge and selection system for reagent containers, sample and reagent aspirating and dispensing probes, a separation system for separating bound from unbound tracer or labeled reagent, a detection system and date collection/processing system. All of th e sub- units of the machine are controlled by a central processing unit to coordina te the activity of all of the subunits of the analyzer. The analyzer is specificall y suited for performing heterogeneous binding assay protocols, particularly immunoassays.
-
公开(公告)号:CA2178296A1
公开(公告)日:1997-01-15
申请号:CA2178296
申请日:1996-06-05
Applicant: CIBA CORNING DIAGNOSTICS CORP
Inventor: POLANIEC JAMES P , LAPEUS DAVID J , WHITESEL MARY BETH
Abstract: A magnetic conveyor system for transporting test samples in tubes disposed in a sample rack having a magnetic or magnetically attractive region is described. The magnetic conveyor system includes a drive system, a magnet coupled to the drive system and movable in response to the drive system and a tray having a first surface adapted to receive the sample rack. The magnet is spaced a predetermined distance from the first surface of the tray such that the magnet provides a magnetic force at the surface of the tray. The magnetic force engages the magnetically attractive region of the sample rack disposed on the tray to thereby move the sample rack along the first surface of the tray in response to movement of the drive system. When the tray reaches the end of the rack it is moved onto a processing queue tray where it is available for test purposes. A barcode reader reads a bar code on each test sample as it is placed on the process queue to identify one or more tests to perform . When all samples have received the individual tests the rack exits to an output queue for disposal. When a test must be made on an immediate basis out of normal processing order a sample rack can be inserted into the process queue via a priority rack feed. In the indicated manner, testing can continue without interruption as new racks are added and completed racks removed.
-
公开(公告)号:AU8789091A
公开(公告)日:1992-09-10
申请号:AU8789091
申请日:1991-11-15
Applicant: CIBA CORNING DIAGNOSTICS CORP
Inventor: CAREY GLEN A , LEWIS SCOTT C , MANN RAYMOND A , WHITESEL MARY BETH , POLANIEC JAMES P , WOYANSKY GEORGE J , PABST STEFAN R , KLINGSHIRN FRANK C
IPC: G01N21/78 , B01L3/00 , G01N21/03 , G01N21/76 , G01N33/53 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , C12M1/00 , G01N35/06 , G01J3/12 , H05B37/02 , H05B3/58 , B01L3/14 , B01L7/00 , B01L11/00
Abstract: Interalia, a luminometer for an automated analyzer to assay an analyte in a test sample in a cuvette in which the product of the test reaction includes a chemiluminescent labeled reagent and the product being suspended in an acid solution, the said cuvette having a bottom wall, side wall and an open top, characterised in that it comprises:(a) a cuvette transport for conveying the said cuvette in a horizontal plane from an entrance point to a base solution dispense point and to an exit point;(b) dispense means at the said base solution dispense point for dispensing a base solution into the said cuvette to cause a chemiluminescent flash;(c) an instrument at the said base solution dispense point for measuring the intensity of the said flash;and(d) control means including a central processing unit for coordinating the said cuvette transport, the said dispense means and the said instrument is disclosed.
-
公开(公告)号:MX9602286A
公开(公告)日:1998-04-30
申请号:MX9602286
申请日:1996-06-11
Applicant: CIBA CORNING DIAGNOSTICS CORP
Inventor: LAPEUS DAVID J , POLANIEC JAMES P
Abstract: En un sistema para instalar, a partir de un suministro de puntas de sonda desechables, una de dichas puntas de sonda en una sonda para cada muestra mediante un sistema analizador de fluido automatizado y para remover la punta después de cada uso para permitir que se instale una punta nueva, un mecanismo para hacer un suministro fresco de puntas disponible a una bandeja portadora y para recibir y desechar las bandejas portadoras vacías. Multiples bandejas de punta de sonda, cada una teniendo una base, una tapa y reteniendo una disposicion de puntas se apila dentro de una canaleta del mecanismo. Un par de brazos se oscilan hacia arriba desde una posicion substancialmente vertical a una posicion horizontal debajo de la canaleta. Un pestillo asociado acopla la tapa de la bandeja más inferior dentro de la canaleta mientras que guías de bandeja, que retienen las bandejas dentro de la canaleta, separan para liberar la bandeja más inferior sobre el par de brazos. Una cremallera de entrega asociada con el sistema analizador recibe la base de bandeja más inferior a partir del par de brazos acoplando la base de bandeja con un par de grapas. La cremallera luego separa la base y las sondas en la misma, al sistema analizador. El par de brazos mientras tanto descienden y vacían la tapa hacia un receptáculo de desperdicio o canaleta de desecho. La cremallera de entrega a continuacion regresa una base vacía a los brazos paralelos, que de manera similar vacían la base vacía hacia el receptáculo de desperdicio o canaleta de desecho. El ciclo se repite removiendo la siguiente bandeja de la canaleta.
-
公开(公告)号:DE69633485D1
公开(公告)日:2004-11-04
申请号:DE69633485
申请日:1996-07-12
Applicant: CIBA CORNING DIAGNOSTICS CORP
Inventor: POLANIEC JAMES P , WHITESEL MARY BETH , LAPEUS DAVID J
Abstract: A magnetic conveyor system for transporting test samples in tubes disposed in a sample rack having a magnetic or magnetically attractive region is described. The magnetic conveyor system includes a drive system, a magnet coupled to the drive system and movable in response to the drive system and a tray having a first surface adapted to receive the sample rack. The magnet is spaced a predetermined distance from the first surface of the tray such that the magnet provides a magnetic force at the surface of the tray. The magnetic force engages the magnetically attractive region of the sample rack disposed on the tray to thereby move the sample rack along the first surface of the tray in response to movement of the drive system. When the tray reaches the end of the rack it is moved onto a processing queue tray where it is available for test purposes. A barcode reader reads a bar code on each test sample as it is placed on the process queue to identify one or more tests to perform. When all samples have received the individual tests the rack exits to an output queue for disposal. When a test must be made on an immediate basis out of normal processing order a sample rack can be inserted into the process queue via a priority rack feed. In the indicated manner, testing can continue without interruption as new racks are added and completed racks removed.
-
公开(公告)号:AU2001195A
公开(公告)日:1995-10-19
申请号:AU2001195
申请日:1995-05-12
Applicant: CIBA CORNING DIAGNOSTICS CORP
Inventor: CAREY GLEN A , LEWIS SCOTT C , MANN RAYMOND A , WHITESEL MARY BETH , POLANIEC JAMES P , WOYANSKY GEORGE J , PABST STEFAN R , KLINGSHIRN FRANK C
IPC: G01N21/78 , B01L3/00 , G01N21/03 , G01N21/76 , G01N33/53 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H05B3/58 , G01J3/12 , B01L11/00
Abstract: Interalia, a luminometer for an automated analyzer to assay an analyte in a test sample in a cuvette in which the product of the test reaction includes a chemiluminescent labeled reagent and the product being suspended in an acid solution, the said cuvette having a bottom wall, side wall and an open top, characterised in that it comprises:(a) a cuvette transport for conveying the said cuvette in a horizontal plane from an entrance point to a base solution dispense point and to an exit point;(b) dispense means at the said base solution dispense point for dispensing a base solution into the said cuvette to cause a chemiluminescent flash;(c) an instrument at the said base solution dispense point for measuring the intensity of the said flash;and(d) control means including a central processing unit for coordinating the said cuvette transport, the said dispense means and the said instrument is disclosed.
-
公开(公告)号:CA2050121A1
公开(公告)日:1992-09-05
申请号:CA2050121
申请日:1991-08-28
Applicant: CIBA CORNING DIAGNOSTICS CORP
Inventor: CAREY GLEN A , POLANIEC JAMES P , LEWIS SCOTT C , WOYANSKY GEORGE J , MANN RAYMOND A , PABST STEFAN R , WHITESEL MARY B , KLINGSHIRN FRANK C
IPC: G01N21/78 , B01L3/00 , G01N21/03 , G01N21/76 , G01N33/53 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , B01L3/14 , G01N21/64
Abstract: An analyzer for performing automated assay testing. The analyzer includes a storage and conveyor system for conveying cuvettes to an incubation or processing conveyor, a storage and selection system for test sample containers, a storage and selection system for reagent containers, sample and reagent aspirating and dispensing probes, a separation system for separating bound from unbound tracer or labeled reagent, a detection system and date collection/processing system. All of the sub-units of the machine are controlled by a central processing unit to coordinate the activity of all of the subunits of the analyzer. The analyzer is specifically suited for performing heterogeneous binding assay protocols, particularly immunoassays.
-
公开(公告)号:AU686774B2
公开(公告)日:1998-02-12
申请号:AU2001195
申请日:1995-05-12
Applicant: CIBA CORNING DIAGNOSTICS CORP
Inventor: CAREY GLEN A , LEWIS SCOTT C , MANN RAYMOND A , WHITESEL MARY BETH , POLANIEC JAMES P , WOYANSKY GEORGE J , PABST STEFAN R , KLINGSHIRN FRANK C
IPC: G01N21/78 , B01L3/00 , G01N21/03 , G01N21/76 , G01N33/53 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H05B3/58 , G01J3/12 , B01L11/00
Abstract: Interalia, a luminometer for an automated analyzer to assay an analyte in a test sample in a cuvette in which the product of the test reaction includes a chemiluminescent labeled reagent and the product being suspended in an acid solution, the said cuvette having a bottom wall, side wall and an open top, characterised in that it comprises:(a) a cuvette transport for conveying the said cuvette in a horizontal plane from an entrance point to a base solution dispense point and to an exit point;(b) dispense means at the said base solution dispense point for dispensing a base solution into the said cuvette to cause a chemiluminescent flash;(c) an instrument at the said base solution dispense point for measuring the intensity of the said flash;and(d) control means including a central processing unit for coordinating the said cuvette transport, the said dispense means and the said instrument is disclosed.
-
公开(公告)号:CA2177233A1
公开(公告)日:1997-01-14
申请号:CA2177233
申请日:1996-05-23
Applicant: CIBA CORNING DIAGNOSTICS CORP
Inventor: LAPEUS DAVID J , POLANIEC JAMES P
Abstract: In a system for installing, from a supply of disposable probe tips, one such probe tip on a probe for each sample by an automated fluid analyzer system and for removing the tip after each use to allow a fresh tip to be installed, a mechanism for making a fresh supply of tips available in a carrier tray and for receiving and disposing of empty carrier trays. Multiple probe tip trays, each having a base, a lid, and holding an array of tips are stacked within a chute of the mechanism. A pair of arms are swung up from a substantially vertical position to a horizontal position beneath the chute. An associated latch engages the lid of the lowermost tray within the chute while tray guides, which hold the trays within the chute, separate to release the lowermost tray onto the pair of arms. A delivery rack associated with the analyzer system receives the lowermost tray base from the pair of arms by engaging the tray base with a pair of clips. The rack then removes the base, and the probes thereon, to the analyzer system. The pair of arms meanwhile lower and dump the lid into a waste receptacle or disposal chute. The delivery rack thereafter returns an empty base to the parallel arms, which similarly dump empty base into the waste receptacle or disposal chute. The cycle is repeated by removing the next tray from the chute.
-
-
-
-
-
-
-
-