公开(公告)号：DE3812595C2

公开(公告)日：1997-07-03

申请号：DE3812595

申请日：1988-04-15

Applicant: COLTHURST LTD ,  PRENDERGAST PATRICK THOMAS

Inventor： PRENDERGAST PATRICK THOMAS

IPC: A61K31/565 ,  A61K31/66 ,  A61K31/715 ,  A61K36/258 ,  A61K38/00 ,  A61K38/06 ,  A61K38/19 ,  A61K38/22 ,  A61K39/395 ,  A61K45/06 ,  A61P31/12 ,  A61P31/18 ,  C07J1/00 ,  C07J31/00 ,  C07J51/00 ,  A61K31/705 ,  C07H3/02 ,  C07H7/033 ,  C07K14/52 ,  C07K16/08

Abstract: Compounds of the general Formula (I) (I) in which R is a hydrogen atom or a bromine atom, and R1 is a hydrogen atom, an SO2OM group wherein M is a hydrogen or sodium atom, various sulphatide or phosphatide groups or a glucuronide group are disclosed for use in the prophylaxis and therapy of retroviral infections, especially infection by Human Immunodeficiency Virus. These compounds may be used concomitantly or in combination with various immunomodulators and/or antiviral agents.

公开(公告)号：GR1002240B

公开(公告)日：1996-04-22

申请号：GR88100248

申请日：1988-04-15

Applicant: COLTHURST LTD ,  PRENDERGAST PATRICK THOMAS

Inventor： PRENDERGAST PATRICK THOMAS

IPC: A61K31/565 ,  A61K31/66 ,  A61K31/715 ,  A61K36/258 ,  A61K38/00 ,  A61K38/06 ,  A61K38/19 ,  A61K38/22 ,  A61K39/395 ,  A61K45/06 ,  A61P31/12 ,  A61P31/18 ,  C07J1/00 ,  C07J31/00 ,  C07J51/00

Abstract: Compounds of the general Formula (I) (I) in which R is a hydrogen atom or a bromine atom, and R1 is a hydrogen atom, an SO2OM group wherein M is a hydrogen or sodium atom, various sulphatide or phosphatide groups or a glucuronide group are disclosed for use in the prophylaxis and therapy of retroviral infections, especially infection by Human Immunodeficiency Virus. These compounds may be used concomitantly or in combination with various immunomodulators and/or antiviral agents.

公开(公告)号：SE503482C2

公开(公告)日：1996-06-24

申请号：SE8801406

申请日：1988-04-15

Applicant: COLTHURST LTD ,  PRENDERGAST PATRICK THOMAS

Inventor： PRENDERGAST PATRICK THOMAS

IPC: A61K31/565 ,  A61K31/66 ,  A61K31/715 ,  A61K36/258 ,  A61K38/00 ,  A61K38/06 ,  A61K38/19 ,  A61K38/22 ,  A61K39/395 ,  A61K45/06 ,  A61P31/12 ,  A61P31/18 ,  C07J1/00 ,  C07J31/00 ,  C07J51/00 ,  A61K31/255 ,  A61K31/00 ,  A61K31/58

Abstract: Compounds of the general Formula (I) (I) in which R is a hydrogen atom or a bromine atom, and R1 is a hydrogen atom, an SO2OM group wherein M is a hydrogen or sodium atom, various sulphatide or phosphatide groups or a glucuronide group are disclosed for use in the prophylaxis and therapy of retroviral infections, especially infection by Human Immunodeficiency Virus. These compounds may be used concomitantly or in combination with various immunomodulators and/or antiviral agents.

公开(公告)号：DE3812595A1

公开(公告)日：1988-10-27

申请号：DE3812595

申请日：1988-04-15

Applicant: COLTHURST LTD ,  PRENDERGAST PATRICK THOMAS

Inventor： PRENDERGAST PATRICK THOMAS

IPC: A61K31/565 ,  A61K31/66 ,  A61K31/715 ,  A61K36/258 ,  A61K38/00 ,  A61K38/06 ,  A61K38/19 ,  A61K38/22 ,  A61K39/395 ,  A61K45/06 ,  A61P31/12 ,  A61P31/18 ,  C07J1/00 ,  C07J31/00 ,  C07J51/00 ,  A61K31/705 ,  C07H3/02 ,  C07H7/033 ,  C07K15/26 ,  C07K5/12

Abstract: Compounds of the general Formula (I) (I) in which R is a hydrogen atom or a bromine atom, and R1 is a hydrogen atom, an SO2OM group wherein M is a hydrogen or sodium atom, various sulphatide or phosphatide groups or a glucuronide group are disclosed for use in the prophylaxis and therapy of retroviral infections, especially infection by Human Immunodeficiency Virus. These compounds may be used concomitantly or in combination with various immunomodulators and/or antiviral agents.

公开(公告)号：FI881773A

公开(公告)日：1988-10-17

申请号：FI881773

申请日：1988-04-15

Applicant: COLTHURST LTD ,  PRENDERGAST PATRICK THOMAS

Inventor： PRENDERGAST PATRICK THOMAS

IPC: A61K31/565 ,  A61K31/66 ,  A61K31/715 ,  A61K36/258 ,  A61K38/00 ,  A61K38/06 ,  A61K38/19 ,  A61K38/22 ,  A61K39/395 ,  A61K45/06 ,  A61P31/12 ,  A61P31/18 ,  C07J1/00 ,  C07J31/00 ,  C07J51/00 ,  A61K

Abstract: Compounds of the general Formula (I) (I) in which R is a hydrogen atom or a bromine atom, and R1 is a hydrogen atom, an SO2OM group wherein M is a hydrogen or sodium atom, various sulphatide or phosphatide groups or a glucuronide group are disclosed for use in the prophylaxis and therapy of retroviral infections, especially infection by Human Immunodeficiency Virus. These compounds may be used concomitantly or in combination with various immunomodulators and/or antiviral agents.

公开(公告)号：NZ224272A

公开(公告)日：1991-09-25

申请号：NZ22427288

申请日：1988-04-15

Applicant: COLTHURST LTD ,  PRENDERGAST PATRICK THOMAS

Inventor： PRENDERGAST PATRICK THOMAS

IPC: A61K31/565 ,  A61K31/66 ,  A61K31/715 ,  A61K36/258 ,  A61K38/00 ,  A61K38/06 ,  A61K38/19 ,  A61K38/22 ,  A61K39/395 ,  A61K45/06 ,  A61P31/12 ,  A61P31/18 ,  C07J1/00 ,  C07J31/00 ,  C07J51/00 ,  A61K31/705

Abstract: Compounds of the general Formula (I) (I) in which R is a hydrogen atom or a bromine atom, and R1 is a hydrogen atom, an SO2OM group wherein M is a hydrogen or sodium atom, various sulphatide or phosphatide groups or a glucuronide group are disclosed for use in the prophylaxis and therapy of retroviral infections, especially infection by Human Immunodeficiency Virus. These compounds may be used concomitantly or in combination with various immunomodulators and/or antiviral agents.

公开(公告)号：OA08729A

公开(公告)日：1989-03-31

申请号：OA59333

申请日：1988-04-15

Applicant: COLTHURST LTD ,  PRENDERGAST PATRICK THOMAS

Inventor： PRENDERGAST PATRICK THOMAS

IPC: A61K31/565 ,  A61K31/66 ,  A61K31/715 ,  A61K36/258 ,  A61K38/00 ,  A61K38/06 ,  A61K38/19 ,  A61K38/22 ,  A61K39/395 ,  A61K45/06 ,  A61P31/12 ,  A61P31/18 ,  C07J1/00 ,  C07J31/00 ,  C07J51/00

Abstract: Compounds of the general Formula (I) (I) in which R is a hydrogen atom or a bromine atom, and R1 is a hydrogen atom, an SO2OM group wherein M is a hydrogen or sodium atom, various sulphatide or phosphatide groups or a glucuronide group are disclosed for use in the prophylaxis and therapy of retroviral infections, especially infection by Human Immunodeficiency Virus. These compounds may be used concomitantly or in combination with various immunomodulators and/or antiviral agents.

公开(公告)号：DK175582B1

公开(公告)日：2004-12-13

申请号：DK208188

申请日：1988-04-15

Applicant: COLTHURST LTD ,  PRENDERGAST PATRICK THOMAS

Inventor： PRENDERGAST PATRICK THOMAS

IPC: A61K31/565 ,  A61K31/66 ,  A61K31/715 ,  A61K36/258 ,  A61K38/00 ,  A61K38/06 ,  A61K38/19 ,  A61K38/22 ,  A61K39/395 ,  A61K45/06 ,  A61P31/12 ,  A61P31/18 ,  C07J1/00 ,  C07J31/00 ,  C07J51/00 ,  A61K31/395

Abstract: Compounds of the general Formula (I) (I) in which R is a hydrogen atom or a bromine atom, and R1 is a hydrogen atom, an SO2OM group wherein M is a hydrogen or sodium atom, various sulphatide or phosphatide groups or a glucuronide group are disclosed for use in the prophylaxis and therapy of retroviral infections, especially infection by Human Immunodeficiency Virus. These compounds may be used concomitantly or in combination with various immunomodulators and/or antiviral agents.

公开(公告)号：GB2204237B

公开(公告)日：1991-02-06

申请号：GB8808864

申请日：1988-04-14

Applicant: COLTHURST LTD ,  PRENDERGAST PATRICK THOMAS

Inventor： PRENDERGAST PATRICK THOMAS

IPC: A61K31/565 ,  A61K31/66 ,  A61K31/715 ,  A61K36/258 ,  A61K38/00 ,  A61K38/06 ,  A61K38/19 ,  A61K38/22 ,  A61K39/395 ,  A61K45/06 ,  A61P31/12 ,  A61P31/18 ,  C07J1/00 ,  C07J31/00 ,  C07J51/00

Abstract: Compounds of the general Formula (I) (I) in which R is a hydrogen atom or a bromine atom, and R1 is a hydrogen atom, an SO2OM group wherein M is a hydrogen or sodium atom, various sulphatide or phosphatide groups or a glucuronide group are disclosed for use in the prophylaxis and therapy of retroviral infections, especially infection by Human Immunodeficiency Virus. These compounds may be used concomitantly or in combination with various immunomodulators and/or antiviral agents.

公开(公告)号：ZA882667B

公开(公告)日：1988-12-28

申请号：ZA882667

申请日：1988-04-15

Applicant: COLTHURST LTD ,  PRENDERGAST PATRICK THOMAS

Inventor： PRENDERGAST PATRICK THOMAS ,  PATRICK THOMAS PRENDERGAST

IPC: A61K20060101 ,  A61K