公开(公告)号：FR2864622A1

公开(公告)日：2005-07-01

申请号：FR0351212

申请日：2003-12-26

Applicant: COMMISSARIAT ENERGIE ATOMIQUE

Inventor： TREBBIA JEAN BAPTISTE ,  CHATON PATRICK ,  GETIN STEPHANE ,  GROSSE PHILIPPE

IPC: G01N33/483 ,  G01N21/17 ,  G01N21/25 ,  G01N21/39 ,  G01N21/59 ,  G01N21/27 ,  G01N33/543 ,  G01N33/68

Abstract: The measuring apparatus contains first (207) and second (209) light reflectors which have at least two mirrors or a matrix of mirrors (208) integrated in a single support, and the first and second reflectors form a system of resonant cavities. A support (200) such as a biochip with a number of biological samples (204) is placed between the first and second reflectors. At least one light pulse with a time span of between 100 picoseconds and 100 nanoseconds is emitted in the resonant cavities, and the responding light signals from the cavities are measured with the aid of one or more photodiodes, enabling the light absorption of the samples, containing DNA or RNA marked by fluorophores, to be determined.

公开(公告)号：FR2864622B1

公开(公告)日：2006-09-22

申请号：FR0351212

申请日：2003-12-26

Applicant: COMMISSARIAT ENERGIE ATOMIQUE

Inventor： TREBBIA JEAN BAPTISTE ,  CHATON PATRICK ,  GETIN STEPHANE ,  GROSSE PHILIPPE

IPC: G01N21/27 ,  G01N33/483 ,  G01N21/17 ,  G01N21/25 ,  G01N21/39 ,  G01N21/59 ,  G01N33/543 ,  G01N33/68

Abstract: The measuring apparatus contains first (207) and second (209) light reflectors which have at least two mirrors or a matrix of mirrors (208) integrated in a single support, and the first and second reflectors form a system of resonant cavities. A support (200) such as a biochip with a number of biological samples (204) is placed between the first and second reflectors. At least one light pulse with a time span of between 100 picoseconds and 100 nanoseconds is emitted in the resonant cavities, and the responding light signals from the cavities are measured with the aid of one or more photodiodes, enabling the light absorption of the samples, containing DNA or RNA marked by fluorophores, to be determined.