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公开(公告)号:WO1990000178A1
公开(公告)日:1990-01-11
申请号:PCT/US1989002893
申请日:1989-06-30
Applicant: COR THERAPEUTICS, INC.
Inventor: COR THERAPEUTICS, INC. , CHARO, Israel, F. , FITZGERALD, Laurence, A. , PHILLIPS, David, R.
IPC: C07K07/08
CPC classification number: C07K14/70557 , A61K38/00 , C07K2319/00 , C07K2319/33 , Y10S530/806
Abstract: Methods and compositions are provided for treating platelet-associated ischemic syndromes utilizing oligopeptides corresponding to regions of the platelet GPIIIa protein. The oligopeptides can be used to block platelet aggregation for numerous applications, and can serve in immunogen to raise receptor-specific antibodies.
Abstract translation: 提供了使用对应于血小板GPIIIa蛋白的区域的寡肽来治疗血小板相关缺血综合征的方法和组合物。 寡肽可用于阻断多种应用的血小板聚集,并可用于免疫原以产生受体特异性抗体。
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公开(公告)号:EP0422125B1
公开(公告)日:1996-10-23
申请号:EP89908344.8
申请日:1989-06-30
Applicant: COR THERAPEUTICS, INC.
Inventor: CHARO, Israel, F. , FITZGERALD, Laurence, A. , PHILLIPS, David, R.
CPC classification number: C07K14/70557 , A61K38/00 , C07K2319/00 , C07K2319/33 , Y10S530/806
Abstract: Methods and compositions are provided for treating platelet-associated ischemic syndromes utilizing oligopeptides corresponding to regions of the platelet GPIIIa protein. The oligopeptides can be used to block platelet aggregation for numerous applications, and can serve in immunogen to raise receptor-specific antibodies.
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公开(公告)号:EP0422125A1
公开(公告)日:1991-04-17
申请号:EP89908344.0
申请日:1989-06-30
Applicant: COR THERAPEUTICS, INC.
Inventor: CHARO, Israel, F. , FITZGERALD, Laurence, A. , PHILLIPS, David, R.
IPC: G01N33 , A61K9 , A61K38 , A61K39 , A61K51 , A61P7 , C07K7 , C07K14 , C07K16 , C07K19 , C12N15 , C12P21 , C12R1
CPC classification number: C07K14/70557 , A61K38/00 , C07K2319/00 , C07K2319/33 , Y10S530/806
Abstract: On a mis au point des procédés et des compositions permettant de traiter des syndromes ischémiques associés aux plaquettes, utilisant des oligopeptides correspondant aux régions de la protéine GPIIIa des plaquettes. On peut utiliser les oligopeptides pour bloquer l'agrégation de plaquettes dans de nombreuses applications. Ils peuvent également servir dans des immunogènes pour augmenter le nombre d'anticorps spécifiques de récepteurs.
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