-
1.发明申请IDENTIFICATION OF Bap-1, A PROTEIN THAT BINDS TO INTEGRIN AND IS INVOLVED IN INTEGRIN-MEDIATED SIGNAL TRANSDUCTION 审中-公开Bap-1的鉴定，蛋白质在蛋白质整合和参与整合信号转导中的作用
公开(公告)号：WO1998022583A1
公开(公告)日：1998-05-28
申请号：PCT/US1997020951
申请日：1997-11-18
Applicant: COR THERAPEUTICS, INC.
Inventor： COR THERAPEUTICS, INC. , LI, Shengfeng , PHILLIPS, David, R.
IPC: C12N15/12
Abstract: The present invention provides the amino acid and nucleotide sequence of a protein that binds to beta 3 integrins, alpha IIb and Src kinase and is involved in integrin mediated signaling. Based on this disclosure, the present invention provides methods for identifying agents that block integrin mediated signaling, methods of using agents that block integrin mediated signaling to modulate biological and pathological processes, and agents that block integrin mediated signaling.
Abstract translation: 本发明提供了结合β3整联蛋白，αIIb和Src激酶并参与整联蛋白介导的信号传导的蛋白质的氨基酸和核苷酸序列。 基于该公开内容，本发明提供了用于鉴定阻断整联蛋白介导的信号传导的试剂的方法，使用阻断整联蛋白介导的信号传导调节生物和病理过程的试剂的方法以及阻断整合素介导的信号传导的试剂。
-
2.发明公开IDENTIFICATION OF Bap-1, A PROTEIN THAT BINDS TO INTEGRIN AND IS INVOLVED IN INTEGRIN-MEDIATED SIGNAL TRANSDUCTION 失效IDENTIFYING BAP-1，即整关系和整合素介导SIGNALUEBERTRAGUNG涉及到蛋白质
公开(公告)号：EP0939815A1
公开(公告)日：1999-09-08
申请号：EP97949458.0
申请日：1997-11-18
Applicant: COR THERAPEUTICS, INC.
Inventor： LI, Shengfeng , PHILLIPS, David, R.
IPC: G01N33 , A61K45 , A61P7 , A61P29 , A61P35 , C07K14 , C07K16 , C07K17 , C12N1 , C12N5 , C12N15 , C12P21 , C12Q1 , A61K38
Abstract: The present invention provides the amino acid and nucleotide sequence of a protein that binds to β3 integrins, αIIb and Src kinase and is involved in integrin mediated signaling. Based on this disclosure, the present invention provides methods for identifying agents that block integrin mediated signaling, methods of using agents that block integrin mediated signaling to modulate biological and pathological processes, and agents that block integrin mediated signaling.
-
Search Results
2
records
(took 0.026 seconds)
