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    SELECTIVE FACTOR Xa INHIBITORS
    3.
    发明申请
    SELECTIVE FACTOR Xa INHIBITORS 审中-公开
    选择性因子Xa抑制剂

    公开(公告)号：WO1998016547A1

    公开(公告)日：1998-04-23

    申请号：PCT/US1997018312

    申请日：1997-10-10

    Applicant: COR THERAPEUTICS, INC.

    Inventor： COR THERAPEUTICS, INC. ,  ZHU, Bing-Yan ,  SCARBOROUGH, Robert, M.

    IPC: C07K05/06

    CPC classification number: C07K5/06191 ,  A61K38/00

    Abstract: Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.

    Abstract translation: 本发明涉及显示抗哺乳动物因子Xa活性的新化合物，其盐及其组合物。 这些化合物在体外或体内用于凝血障碍的预防性或治疗性治疗。

    SELECTIVE FACTOR Xa INHIBITORS
    4.
    发明申请
    SELECTIVE FACTOR Xa INHIBITORS 审中-公开
    选择性因子Xa抑制剂

    公开(公告)号：WO1998016525A1

    公开(公告)日：1998-04-23

    申请号：PCT/US1997018647

    申请日：1997-10-10

    Applicant: COR THERAPEUTICS, INC.

    Inventor： COR THERAPEUTICS, INC. ,  ZHU, Bing-Yan ,  SCARBOROUGH, Robert, M.

    IPC: C07D417/14

    CPC classification number: C07D417/12 ,  C07F5/025

    Abstract: Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.

    Abstract translation: 本发明涉及具有抗哺乳动物因子Xa活性的新化合物及其盐和相关组合物。 这些化合物在体外或体内可用于预防或治疗凝血病症。

    2- 1H]-QUINOLONE AND 2- 1H]-QUINOXALONE INHIBITORS OF FACTOR Xa
    6.
    发明公开
    2- 1H]-QUINOLONE AND 2- 1H]-QUINOXALONE INHIBITORS OF FACTOR Xa 审中-公开
    2-1H] - 奎宁酮和2-1H] - 喹喔啉抑制因子Xa

    公开(公告)号：EP1255741A2

    公开(公告)日：2002-11-13

    申请号：EP01906827.9

    申请日：2001-02-01

    Applicant: COR THERAPEUTICS, INC.

    Inventor： ZHU, Bing-Yan ,  SCARBOROUGH, Robert

    IPC: C07D241/44 ,  C07D401/12 ,  C07D401/14 ,  A61K31/497 ,  A61P9/02

    CPC classification number: C07D401/12 ,  C07D241/44 ,  C07D401/14

    Abstract: Novel compounds of general formula I, including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivative having activity against mammalian factor Xa is described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating conditions in mammals characterized by undesired thrombosis.

    Abstract translation: 描述了具有抗哺乳动物因子Xa活性的通式I的新化合物，包括它们的药学上可接受的异构体，盐，水合物，溶剂合物和前药衍生物。 还描述了含有这些化合物的组合物。 这些化合物和组合物可用于体外或体内预防或治疗以不希望的血栓形成为特征的哺乳动物的病症。

    SELECTIVE FACTOR Xa INHIBITORS
    7.
    发明公开
    SELECTIVE FACTOR Xa INHIBITORS 审中-公开
    选择性因子Xa抑制剂

    公开(公告)号：EP0994892A1

    公开(公告)日：2000-04-26

    申请号：EP98938486.2

    申请日：1998-08-11

    Applicant: COR THERAPEUTICS, INC.

    Inventor： ZHU, Bing-Yan ,  SCARBOROUGH, Robert, M.

    IPC: C07K5/06 ,  A61K38/05

    CPC classification number: C07K5/06139 ,  A61K38/00

    Abstract: Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders and have formula (I).

    Abstract translation: 公开了具有抗哺乳动物因子Xa活性的新化合物，其盐及其组合物。 该化合物在体外或体内用于预防或治疗凝血病症并具有式（I）。

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