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公开(公告)号：JPS56119854A
公开(公告)日：1981-09-19
申请号：JP1033281
申请日：1981-01-28
Applicant: COULTER ELECTRONICS
Inventor： GIYUNTAA JINSUBAAGU , BURUUSU JIEI HOTSUGINSU
Abstract: A sample and stat feeding system (10) for sequentially supplying a renewable supply of cuvettes (20) with aliquots of sample liquids in a continuous processing mode. The sample liquids are contained in an annular sample tray (50) having a plurality of sample vessels molded into the tray. The sample containers form two or more annular rows (56, 58) on the outer edge of the tray in which routine samples are maintained in an ordered sequence. Emergency samples (stats) and controls (standards) are maintained in separate auxiliary locations or arrays of locations (54) which may be molded or separate cups placed in tray cavities. A sample pick up mechanism has a pick up probe (36) which is rotated to define an arc across at least substantial portion of the tray (50) and at least one stat location. The tray (50) is rotated to align the sample, stat and control cavities with the arc of the probe. Sample aliquots are picked up and dispensed into the cuvettes (20) in a programed operation sequence, with each sample fluid being related to a particular patient and programed for one or more analytical tests such as measuring the chemical reaction resulting from the addition of one or more reagents from a reagent supply. The program sequencing includes inserting a control aliquot in some of the cuvettes (20) at a predetermined frequency to monitor the accuracy of the machine. When a stat test occurs, the stat is inserted in the tray (50) and the programed sequence is interrupted to load the stat into the reaction vessel. The order of sample locations is not disturbed since the stats and controls are maintained in separate locations. The sample tray (50) preferably wilt be molded of inexpensive material so it may be thrown away after all sample aliquots have been loaded into respective cuvettes for testina.
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公开(公告)号：JPS56150357A
公开(公告)日：1981-11-20
申请号：JP1032981
申请日：1981-01-28
Applicant: COULTER ELECTRONICS
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公开(公告)号：JPS56119853A
公开(公告)日：1981-09-19
申请号：JP1033181
申请日：1981-01-28
Applicant: COULTER ELECTRONICS
Inventor： GIYUNTAA JINSUBAAGU , TOOMASU HOON
Abstract: System and program for measuring progressively the absorbance changes of a large number of aliquots from a plurality of different samples in a continuous processing mode. A plurality of routine samples are maintained in an ordered sequence in a sample tray which may be moved to a first sample pick up position. Emergency samples (stats) and controls (standards) are positioned in a second plurality of auxiliary positions which may be moved to a second sample position. A first and second plurality of reagents are maintained, moved to respective reagent pick up positions, picked up, moved and dispensed in respective dispensing positions by respective single reagent dispensing arms in a similar manner to the sample operation. The chemical reaction is then monitored by photometer means preferably having a plurality of photometric detectors such that radiation passes through each of the cuvettes and the fluids therein during each cycle of the system. Just prior to the sample dispensing position the cuvette is cleaned and tested to ensure that all the previously added fluids have been removed prior to receiving a new sample. Any one sample may be tested with different reagents or reagent mixtures in different aliquots placed in separate cuvettes at each wavelength as desired. Each sample aliquot and reagent mixture may be measured to determine the rate of the chemical reaction and the equilibrium or end point of the reaction or both, if desired. The array of cuvettes is continuous, because it is replenished at the end of each sequence prior to the addition of the new sample.
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