公开(公告)号：US10227313B2

公开(公告)日：2019-03-12

申请号：US15868848

申请日：2018-01-11

Applicant: CYTEC INDUSTRIES INC.

Inventor： Ram B. Gupta ,  Manav Gupta

IPC: C07D265/16 ,  C07D413/10 ,  C07D413/14 ,  C07C315/04 ,  C07C317/36

Abstract: A synthesis process for making a benzoxazine compound containing at least one benzoxazine unit from aromatic amine containing at least one primary amino group, at least one phenolic compound with at least one ortho-hydrogen, and alkyl formcel. In one embodiment, the aromatic amine is reacted with alkyl formcel to generate an alkoxymethyl intermediate compound. Subsequently, the intermediate compound is reacted with a phenol to generate the benzoxazine compound. In another embodiment, the benzoxazine compound is formed by reacting aromatic amine with alkyl formcel and phenol in one reaction step. Also disclosed is a method for isolating the alkoxymethyl compound formed by reacting aromatic amine with alkyl formcel. The isolated alkoxymethyl compound is useful as a reactant in a subsequent reaction.

公开(公告)号：US20180127387A1

公开(公告)日：2018-05-10

申请号：US15868848

申请日：2018-01-11

Applicant: CYTEC INDUSTRIES INC.

Inventor： Ram B. Gupta ,  Martin Cohen ,  Manav Gupta

IPC: C07D265/16 ,  C07C317/36 ,  C07D413/10 ,  C07C315/04 ,  C07D413/14

CPC classification number: C07D265/16 ,  C07C315/04 ,  C07C317/36 ,  C07D413/10 ,  C07D413/14

Abstract: A synthesis process for making a benzoxazine compound containing at least one benzoxazine unit from aromatic amine containing at least one primary amino group, at least one phenolic compound with at least one ortho-hydrogen, and alkyl formcel. In one embodiment, the aromatic amine is reacted with alkyl formcel to generate an alkoxymethyl intermediate compound. Subsequently, the intermediate compound is reacted with a phenol to generate the benzoxazine compound. In another embodiment, the benzoxazine compound is formed by reacting aromatic amine with alkyl formcel and phenol in one reaction step. Also disclosed is a method for isolating the alkoxymethyl compound formed by reacting aromatic amine with alkyl formcel. The isolated alkoxymethyl compound is useful as a reactant in a subsequent reaction.

公开(公告)号：US09902706B2

公开(公告)日：2018-02-27

申请号：US14919186

申请日：2015-10-21

Applicant: Cytec Industries Inc.

Inventor： Ram B Gupta ,  Martin Cohen ,  Manav Gupta

IPC: C07D265/16 ,  C07D413/10 ,  C07D413/14 ,  C07C315/04

CPC classification number: C07D265/16 ,  C07C315/04 ,  C07C317/36 ,  C07D413/10 ,  C07D413/14

Abstract: A synthesis process for making a benzoxazine compound containing at least one benzoxazine unit from aromatic amine containing at least one primary amino group, at least one phenolic compound with at least one ortho-hydrogen, and alkyl formcel. In one embodiment, the aromatic amine is reacted with alkyl formcel to generate an alkoxymethyl intermediate compound. Subsequently, the intermediate compound is reacted with a phenol to generate the benzoxazine compound. In another embodiment, the benzoxazine compound is formed by reacting aromatic amine with alkyl formcel and phenol in one reaction step. Also disclosed is a method for isolating the alkoxymethyl compound formed by reacting aromatic amine with alkyl formcel. The isolated alkoxymethyl compound is useful as a reactant in a subsequent reaction.

公开(公告)号：US20160115139A1

公开(公告)日：2016-04-28

申请号：US14919186

申请日：2015-10-21

Applicant: Cytec Industries Inc.

Inventor： Ram B Gupta ,  Martin Cohen ,  Manav Gupta

IPC: C07D265/16 ,  C07D413/14 ,  C07D413/10

CPC classification number: C07D265/16 ,  C07C315/04 ,  C07C317/36 ,  C07D413/10 ,  C07D413/14

Abstract: A synthesis process for making a benzoxazine compound containing at least one benzoxazine unit from aromatic amine containing at least one primary amino group, at least one phenolic compound with at least one ortho-hydrogen, and alkyl formcel. In one embodiment, the aromatic amine is reacted with alkyl formcel to generate an alkoxymethyl intermediate compound. Subsequently, the intermediate compound is reacted with a phenol to generate the benzoxazine compound. In another embodiment, the benzoxazine compound is formed by reacting aromatic amine with alkyl formcel and phenol in one reaction step. Also disclosed is a method for isolating the alkoxymethyl compound formed by reacting aromatic amine with alkyl formcel. The isolated alkoxymethyl compound is useful as a reactant in a subsequent reaction.

Abstract translation: 一种由含有至少一个伯氨基的芳族胺，至少一种具有至少一个邻位氢的酚类化合物和烷基形式制备含有至少一种苯并恶嗪单元的苯并恶嗪化合物的合成方法。 在一个实施方案中，芳族胺与烷基形式反应以产生烷氧基甲基中间体化合物。 随后，将中间体化合物与苯酚反应以产生苯并恶嗪化合物。 在另一个实施方案中，苯并恶嗪化合物是通过在一个反应​​步骤中使芳族胺与烷基形式和苯酚反应形成的。 还公开了一种分离由芳族胺与烷基甲酸反应形成的烷氧基甲基化合物的方法。 分离的烷氧基甲基化合物可用作随后反应中的反应物。