公开(公告)号：US20240169943A1

公开(公告)日：2024-05-23

申请号：US18224694

申请日：2023-07-21

Applicant: CYTESI, INC.

Inventor： Tung-Yu WU ,  Chung-Yi WANG ,  Tang-Hung PO

IPC: G09G3/34

CPC classification number: G09G3/348 ,  G09G2300/0842 ,  G09G2300/0871

Abstract: An apparatus including a pixel electrode circuit is provided. The pixel electrode circuit includes a first switch, a second switch, a first-type transistor, a first second-type transistor, and a second second-type transistor. The first switch and the second switch are respectively controlled by a first control signal and a second control signal. The first-type transistor includes a gate electrically connected to a first node, a first terminal connected to a first power supply voltage, and a second terminal connected to a third node. The first second-type transistor includes a gate electrically connected to a second node, a first terminal connected to a second power supply voltage, and a second terminal connected to the third node. The second second-type transistor includes a gate electrically connected to the second node, a first terminal being grounded, and a second terminal providing an output voltage.

公开(公告)号：US20250043330A1

公开(公告)日：2025-02-06

申请号：US18793259

申请日：2024-08-02

Applicant: CYTESI, INC.

Inventor： Tung-Yu WU

IPC: C12Q1/6806 ,  C12Q1/6851

Abstract: Provided is a method for molecule quantification. The method comprises: utilizing an electrowetting-on-dielectric (EWOD) device to split a target droplet into a plurality of sub-droplets; performing a quantitative polymerase chain reaction (qPCR) test on at least one of the plurality of sub-droplets within the EWOD device; and obtaining a result of the qPCR test on the at least one of the plurality of sub-droplets to determine whether the result of the qPCR test is positive or negative.

公开(公告)号：US20240169944A1

公开(公告)日：2024-05-23

申请号：US18377614

申请日：2023-10-06

Applicant: CYTESI, INC.

Inventor： Tung-Yu WU ,  Chung-Yi WANG ,  Tang-Hung PO

IPC: G09G3/34

CPC classification number: G09G3/348 ,  G09G2300/0842 ,  G09G2300/0871

Abstract: An apparatus including a pixel electrode circuit is provided. The pixel electrode circuit includes a first switch, a second switch, a first-type transistor, a first second-type transistor, and a second second-type transistor. The first switch and the second switch are respectively controlled by a first control signal and a second control signal. The first-type transistor includes a gate electrically connected to a first node, a first terminal connected to a first power supply voltage, and a second terminal connected to a third node. The first second-type transistor includes a gate electrically connected to a second node, a first terminal connected to a second power supply voltage, and a second terminal connected to the third node. The second second-type transistor includes a gate electrically connected to the second node, a first terminal being grounded, and a second terminal providing an output voltage.

公开(公告)号：US20250041852A1

公开(公告)日：2025-02-06

申请号：US18793524

申请日：2024-08-02

Applicant: CYTESI, INC.

Inventor： Tung-Yu WU ,  Tsung-Yuan WU ,  Jun-Chao LU

IPC: B01L3/00

Abstract: Provided is a hydraulic multiport connection design for a microfluidic device. The electrowetting on dielectric (EWOD) system comprises a first connection device including a first housing, a first port, a second port, and a first channel within the first housing, the first channel coupling to the first port and the second port. A second connection device is coupled to the first connection device. The second connection device includes a second housing, a third port, a fourth port and a second channel within the second housing, the second channel coupling to the third port and the fourth port. The first connection device and the second connection device are coupled by securely engaging the second port to the third port. The second port and the third port are configured to be engaged seamlessly.

公开(公告)号：US20230110598A1

公开(公告)日：2023-04-13

申请号：US17955853

申请日：2022-09-29

Applicant: CYTESI, INC.

Inventor： Tung-Yu WU ,  Tang-Hung PO

IPC: B01L3/00

Abstract: A microfluidic apparatus is provided for manipulating and sensing the droplets of fluid. The microfluidic apparatus includes an electrowetting on dielectric (EWOD) device and a sensing device. The EWOD device receives one or more droplets of fluid, and includes a plurality of electrode elements arranged in an array of rows and columns. The sensing device is disposed external or internal to the EWOD device and includes a plurality of optical sensors corresponding to the electrode elements of the EWOD device, respectively. Therefore, it is possible to reduce the cost and/or volume of the microfluidic apparatus.

公开(公告)号：US20240382965A1

公开(公告)日：2024-11-21

申请号：US18666403

申请日：2024-05-16

Applicant: CYTESI, INC

Inventor： Tung-Yu WU ,  Tsung-Yuan WU

IPC: B01L3/00

Abstract: Provided is an electrowetting-on-dielectric (EWOD) device. The EWOD device comprises a first substrate and a second substrate opposite to the first substrate. The first substrate comprises a plurality of first electrodes configured to be respectively controllably connected to signal lines. The first hydrophobic layer disposed over the plurality of first electrodes. The second substrate comprises a second electrode configured to be connected to the signal lines. The second hydrophobic layer disposed over the second electrode. An internal space between the first substrate and the second substrate is provided for receiving a droplet and a surrounding medium. The droplet is surrounded by the surrounding medium.

公开(公告)号：US20240165625A1

公开(公告)日：2024-05-23

申请号：US18510613

申请日：2023-11-15

Applicant: CYTESI, INC.

Inventor： Tung-Yu WU ,  Chung-Yi WANG ,  Tang-Hung PO

IPC: B01L3/00

CPC classification number: B01L3/502792 ,  B01L3/502715 ,  B01L2300/0645 ,  B01L2400/0427

Abstract: An apparatus and a system are provided. The system includes a top plate electrode, a dielectric layer, a plurality of pixel electrode circuits, and a plurality of detection circuits. A droplet is disposed between the top plate electrode and the dielectric layer. The plurality of pixel electrode circuits are arranged in a two-dimensional array. The pixel electrode circuits in each column of the two-dimensional array are electrically connected to a respective detection circuit of the plurality of detection circuits.

公开(公告)号：US20230221543A1

公开(公告)日：2023-07-13

申请号：US18092656

申请日：2023-01-03

Applicant: CYTESI, INC.

Inventor： Tung-Yu WU ,  Chung-Yi WANG ,  Tang-Hung PO

IPC: G02B26/00 ,  B01L3/00

CPC classification number: G02B26/005 ,  B01L3/50273 ,  B01L2400/0427

Abstract: A driving circuit for an electrowetting on dielectric (EWOD) pixel. The driving circuit includes a latch circuit for transmitting a source data pulse to a storage capacitor in response to an activation gate signal applied to the gate of the switch transistor and generating a latch voltage and an inversion circuit for outputting a driving voltage at either a first power voltage or a second power voltage based on the latch voltage generated by the latch circuit.

公开(公告)号：US20230191406A1

公开(公告)日：2023-06-22

申请号：US18074142

申请日：2022-12-02

Applicant: CYTESI, INC.

Inventor： Tung-Yu WU ,  Tang-Hung PO ,  CHUNG-YI WANG

IPC: B01L3/00 ,  B81B7/00 ,  B01L7/00

CPC classification number: B01L3/50273 ,  B01L7/54 ,  B81B7/0096 ,  B01L2300/0645 ,  B01L2300/1827 ,  B01L2400/0427 ,  B81B2201/057

Abstract: There is provided a heating device to independently and/or effectively heat the micro objects manipulated by a micro apparatus/system, for example the droplets of fluids in an electrowetting on dielectric EWOD device of a microfluidic apparatus. The heating device may include a plurality of micro heaters arranged in an array of rows and columns, and the micro heaters of the heating device may be disposed in relative to the electrode elements of the EWOD device, respectively. Therefore, the micro heaters of the heating device may heat one of the electrode elements of the EWOD device, thereby preventing thermal effect of the micro object on the other electrode elements.