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    Microfluidic controller detector system with self-calibration
    2.
    发明申请
    Microfluidic controller detector system with self-calibration 有权
    微流控制器检测系统具有自校准功能

    公开(公告)号：US20030011382A1

    公开(公告)日：2003-01-16

    申请号：US10215885

    申请日：2002-08-09

    Applicant: CALIPER TECHNOLOGIES CORP.

    Inventor： Calvin Y.H. Chow ,  Morten J. Jensen ,  Colin B. Kennedy ,  Michael M. Lacy ,  Robert E. Nagle

    IPC: G01R035/00

    CPC classification number: G01N27/44721 ,  B01L3/5027 ,  B01L9/527 ,  B01L2200/027 ,  B01L2200/148 ,  B01L2400/0415 ,  G01N27/44791

    Abstract: A microfluidic controller and detector system and method for performing screening assays are disclosed. The microfluidic controller and detector system comprises a fluidic chip that includes at least two intersecting channels and a detection zone, a fluid direction system comprising an electrical interface configured for electrical contact with the at least two intersecting channels, an optics block having an objective lens disposed adjacent the detection zone, and a control system coupled to the optics block and adapted to receive and analyze data from the optics block. The electrical interface generally includes electrodes configured for electrical contact with the intersecting channels and coupled to electrode channels for supplying electrical input to the electrodes. A reference channel is optionally provided to calibrate the electrode channels.

    Abstract translation: 公开了用于进行筛选测定的微流控制器和检测器系统和方法。 微流控制器和检测器系统包括流体芯片，其包括至少两个相交通道和检测区域，流体方向系统，包括被配置为与所述至少两个相交通道电接触的电接口， 邻近所述检测区域，以及控制系统，其耦合到所述光学块并适于从所述光学块接收和分析数据。 电接口通常包括被配置为与交叉通道电接触并且耦合到用于向电极提供电输入的电极通道的电极。 可选地提供参考通道以校准电极通道。

    Container providing a controlled hydrated environment
    4.
    发明申请
    Container providing a controlled hydrated environment 有权
    集装箱提供受控的水合环境

    公开(公告)号：US20040238401A1

    公开(公告)日：2004-12-02

    申请号：US10449517

    申请日：2003-06-02

    Applicant: Caliper Technologies Corp.

    Inventor： Michael Greenstein ,  Colin B. Kennedy ,  Huan L. Phan ,  Stephan Bianchi ,  Jonathan R. Harris ,  Daren W. Hebold ,  Robert A. Howard ,  Andrew L. Zee

    IPC: B65D085/00

    CPC classification number: B01L9/527 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2200/185 ,  B01L2300/041 ,  B65D85/70

    Abstract: A container is provided for shipping and storing a pre-wetted and pre-conditioned microfluidic nullsippernull chip. The container contains both dry compartments and wet compartments. A base contains a fluid-filled reservoir configured to house the capillaries. The opening of the reservoir is sealed with an O-ring. The plastic mount of the chip rests on the base in a dry compartment. The upper surface of the chip contains several wells containing fluid. A gasket is provided with plugs configured to be disposed within and seal the wells. Alternatively, the wells are first sealed with a foil film adhered to the well openings with an adhesive and a gasket is disposed between the foil and a cover, which is removably attached to the base. When the cover is closed, the gasket and O-ring seal the wet compartments to prevent leakage and to slow evaporation.

    Abstract translation: 提供了用于运输和存储预润湿和预调节微流控“吸嘴”芯片的容器。 容器包含干燥隔室和湿隔间。 基座包含配置成容纳毛细管的流体填充的储存器。 储罐的开口用O形圈密封。 芯片的塑料安装座位于干燥隔间的底座上。 芯片的上表面包含几个含有流体的孔。 垫圈设置有被配置为设置在井中并密封井的塞子。 或者，孔首先用粘合剂粘附到井口上的箔膜密封，并且垫片设置在箔和盖之间，盖可拆卸地附接到基座。 当盖子关闭时，垫圈和O形圈密封湿隔间，以防止泄漏并减缓蒸发。

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