公开(公告)号：US10323245B2

公开(公告)日：2019-06-18

申请号：US15601446

申请日：2017-05-22

Applicant: Commonwealth Scientific and Industrial Research Organisation

Inventor： Steven Whyard ,  Fiona Helen Cameron ,  Minoo Moghaddam ,  Trevor J. Lockett

IPC: A61K48/00 ,  C07H21/02 ,  C07H21/04 ,  C12N15/113 ,  A01K67/033 ,  C12N15/11 ,  A01N57/16 ,  A61K31/713 ,  A61K38/00

Abstract: The invention is to methods of gene silencing in arthropods using dsRNA. The method is include contacting the arthropod with, and/or directly feeding the arthropod, the dsRNA to the arthropods to deliver the dsRNA to arthropod tissues. It is envisaged that the methods of the invention will have use in determining the biological function of genes in arthropods. Methods of pest control of arthropods, and of protecting arthropods against parasites and predators are provided. Transgenic arthropods expressing dsRNA molecules are also provided by the present invention.

公开(公告)号：US20170260528A1

公开(公告)日：2017-09-14

申请号：US15601446

申请日：2017-05-22

Applicant: Commonwealth Scientific and Industrial Research Organisation

Inventor： Steven Whyard ,  Fiona Helen Cameron ,  Minoo Moghaddam ,  Trevor J. Lockett

IPC: C12N15/113 ,  A01K67/033

CPC classification number: C12N15/113 ,  A01K67/0337 ,  A01K2217/05 ,  A01N57/16 ,  A61K31/713 ,  A61K38/00 ,  C12N15/111 ,  C12N15/1137 ,  C12N2310/14 ,  C12N2320/32 ,  C12N2320/50 ,  C12Y302/01031

Abstract: The invention is to methods of gene silencing in arthropods using dsRNA. The method is include contacting the arthropod with, and/or directly feeding the arthropod, the dsRNA to the arthropods to deliver the dsRNA to arthropod tissues. It is envisaged that the methods of the invention will have use in determining the biological function of genes in arthropods. Methods of pest control of arthropods, and of protecting arthropods against parasites and predators are provided. Transgenic arthropods expressing dsRNA molecules are also provided by the present invention.

公开(公告)号：US20150275214A1

公开(公告)日：2015-10-01

申请号：US14740422

申请日：2015-06-16

Applicant: Commonwealth Scientific and Industrial Research Organisation

Inventor： Steven Whyard ,  Fiona Helen Cameron ,  Minoo Moghaddam ,  Trevor J. Lockett

IPC: C12N15/113 ,  A01N57/16

CPC classification number: C12N15/113 ,  A01K67/0337 ,  A01K2217/05 ,  A01N57/16 ,  A61K31/713 ,  A61K38/00 ,  C12N15/111 ,  C12N15/1137 ,  C12N2310/14 ,  C12N2320/32 ,  C12N2320/50 ,  C12Y302/01031

Abstract: The invention is to methods of gene silencing in arthropods using dsRNA. The method is include contacting the arthropod with, and/or directly feeding the arthropod, the dsRNA to the arthropods to deliver the dsRNA to arthropod tissues. It is envisaged that the methods of the invention will have use in determining the biological function of genes in arthropods. Methods of pest control of arthropods, and of protecting arthropods against parasites and predators are provided. Transgenic arthropods expressing dsRNA molecules are also provided by the present invention.

Abstract translation: 本发明是利用dsRNA在节肢动物中进行基因沉默的方法。 该方法包括将节肢动物与节肢动物接触和/或直接喂食节肢动物，将dsRNA与节肢动物接触以将dsRNA递送至节肢动物组织。 预期本发明的方法将用于确定节肢动物中基因的生物学功能。 提供了节肢动物病虫害防治方法以及保护节肢动物免受寄生虫和捕食者的伤害。 表达dsRNA分子的转基因节肢动物也由本发明提供。

公开(公告)号：US09085770B2

公开(公告)日：2015-07-21

申请号：US14521184

申请日：2014-10-22

Applicant: Commonwealth Scientific and Industrial Research Organisation

Inventor： Steven Whyard ,  Fiona Helen Cameron ,  Minoo Moghaddam ,  Trevor J. Lockett

IPC: C07H21/02 ,  C07H21/04 ,  A61K48/00 ,  C12N15/113 ,  A01K67/033 ,  C12N15/11 ,  A01N57/16 ,  A61K31/713 ,  A61K38/00

CPC classification number: C12N15/113 ,  A01K67/0337 ,  A01K2217/05 ,  A01N57/16 ,  A61K31/713 ,  A61K38/00 ,  C12N15/111 ,  C12N15/1137 ,  C12N2310/14 ,  C12N2320/32 ,  C12N2320/50 ,  C12Y302/01031

Abstract: The invention is to methods of gene silencing in arthropods using dsRNA. The method is include contacting the arthropod with, and/or directly feeding the arthropod, the dsRNA to the arthropods to deliver the dsRNA to arthropod tissues. It is envisaged that the methods of the invention will have use in determining the biological function of genes in arthropods. Methods of pest control of arthropods, and of protecting arthropods against parasites and predators are provided. Transgenic arthropods expressing dsRNA molecules are also provided by the present invention.

Abstract translation: 本发明是利用dsRNA在节肢动物中进行基因沉默的方法。 该方法包括将节肢动物与节肢动物接触和/或直接喂食节肢动物，将dsRNA与节肢动物接触以将dsRNA递送至节肢动物组织。 预期本发明的方法将用于确定节肢动物中基因的生物学功能。 提供了节肢动物病虫害防治方法以及保护节肢动物免受寄生虫和捕食者的伤害。 表达dsRNA分子的转基因节肢动物也由本发明提供。

公开(公告)号：US20190316128A1

公开(公告)日：2019-10-17

申请号：US16436183

申请日：2019-06-10

Applicant: Commonwealth Scientific and Industrial Research Organisation

Inventor： Steven Whyard ,  Fiona Helen Cameron ,  Minoo Moghaddam ,  Trevor J. Lockett

IPC: C12N15/113 ,  A01N57/16 ,  C12N15/11 ,  A61K31/713 ,  A01K67/033

Abstract: The invention is to methods of gene silencing in arthropods using dsRNA. The method is include contacting the arthropod with, and/or directly feeding the arthropod, the dsRNA to the arthropods to deliver the dsRNA to arthropod tissues. It is envisaged that the methods of the invention will have use in determining the biological function of genes in arthropods. Methods of pest control of arthropods, and of protecting arthropods against parasites and predators are provided. Transgenic arthropods expressing dsRNA molecules are also provided by the present invention.

公开(公告)号：US09663786B2

公开(公告)日：2017-05-30

申请号：US14740422

申请日：2015-06-16

Applicant: Commonwealth Scientific and Industrial Research Organisation

Inventor： Steven Whyard ,  Fiona Helen Cameron ,  Minoo Moghaddam ,  Trevor J. Lockett

IPC: C07H21/02 ,  C07H21/04 ,  A61K48/00 ,  C12N15/113 ,  A01K67/033 ,  C12N15/11 ,  A01N57/16 ,  A61K31/713 ,  A61K38/00

CPC classification number: C12N15/113 ,  A01K67/0337 ,  A01K2217/05 ,  A01N57/16 ,  A61K31/713 ,  A61K38/00 ,  C12N15/111 ,  C12N15/1137 ,  C12N2310/14 ,  C12N2320/32 ,  C12N2320/50 ,  C12Y302/01031

Abstract: The invention is to methods of gene silencing in arthropods using dsRNA. The method is include contacting the arthropod with, and/or directly feeding the arthropod, the dsRNA to the arthropods to deliver the dsRNA to arthropod tissues. It is envisaged that the methods of the invention will have use in determining the biological function of genes in arthropods. Methods of pest control of arthropods, and of protecting arthropods against parasites and predators are provided. Transgenic arthropods expressing dsRNA molecules are also provided by the present invention.

公开(公告)号：US20150047063A1

公开(公告)日：2015-02-12

申请号：US14521184

申请日：2014-10-22

Applicant: Commonwealth Scientific and Industrial Research Organisation

Inventor： Steven Whyard ,  Fiona Helen Cameron ,  Minoo Moghaddam ,  Trevor J. Lockett

IPC: C12N15/113 ,  A01N57/16

CPC classification number: C12N15/113 ,  A01K67/0337 ,  A01K2217/05 ,  A01N57/16 ,  A61K31/713 ,  A61K38/00 ,  C12N15/111 ,  C12N15/1137 ,  C12N2310/14 ,  C12N2320/32 ,  C12N2320/50 ,  C12Y302/01031

Abstract: The invention is to methods of gene silencing in arthropods using dsRNA. The method is include contacting the arthropod with, and/or directly feeding the arthropod, the dsRNA to the arthropods to deliver the dsRNA to arthropod tissues. It is envisaged that the methods of the invention will have use in determining the biological function of genes in arthropods. Methods of pest control of arthropods, and of protecting arthropods against parasites and predators are provided. Transgenic arthropods expressing dsRNA molecules are also provided by the present invention.