公开(公告)号：WO2020168052A1

公开(公告)日：2020-08-20

申请号：PCT/US2020/018074

申请日：2020-02-13

Applicant: CREATV MICROTECH, INC.

Inventor： ADAMS, Daniel L. ,  TANG, Cha-Mei

IPC: G01N33/50 ,  G01N33/574

Abstract: Means for predicting overall survival (OS) and progression free survival (PFS) of subjects having cancer are disclosed, where the predictions are based on the number of CCR5 pools in circulating cells, such as circulating cancer associated macrophage-like cells (CAMLs) and circulating tumor cells (CTCs) found in a biological sample, such as blood, from the subject. CCR5 expression can also be used for companion or complementary diagnostics.

公开(公告)号：WO2023283264A1

公开(公告)日：2023-01-12

申请号：PCT/US2022/036253

申请日：2022-07-06

Applicant: CREATV MICROTECH INC.

Inventor： ADAMS, Daniel L. ,  TANG, Cha-Mei

IPC: G01N33/50 ,  G01N33/574 ,  G01N33/483

Abstract: Means for predicting (i) multiple organ metastasis and/or multifocal metastatic disease and (ii) overall survival (OS) and progression free survival (PFS) of subjects having cancer are disclosed, where the predictions are based on the number and size of circulating cancer associated macrophage-like cells (CAMLs) found in a biological sample, such as blood, from the subject.

公开(公告)号：WO2023004038A1

公开(公告)日：2023-01-26

申请号：PCT/US2022/037874

申请日：2022-07-21

Applicant: CREATV MICROTECH INC.

Inventor： ADAMS, Daniel L. ,  TANG, Cha-Mei

IPC: G01N33/483 ,  G01N33/574 ,  G01N33/569

Abstract: Means for predicting treatment response in a subject having cancer are disclosed, where the predictions are based comparing the number and size of circulating cancer associated macrophage-like cells (CAMLs) and circulating tumor cells (CTCs) found in biological samples at baseline and after induction of therapy, such as blood, from the subject.

公开(公告)号：EP3924733A1

公开(公告)日：2021-12-22

申请号：EP20710020.7

申请日：2020-02-13

Applicant: Creatv Microtech, Inc.

Inventor： ADAMS, Daniel L. ,  TANG, Cha-Mei

IPC: G01N33/50 ,  G01N33/574

公开(公告)号：EP4367515A1

公开(公告)日：2024-05-15

申请号：EP22838352.7

申请日：2022-07-06

Applicant: Creatv Microtech, Inc.

Inventor： ADAMS, Daniel L. ,  TANG, Cha-Mei

IPC: G01N33/50 ,  G01N33/574 ,  G01N33/483

CPC classification number: G01N33/57492 ,  G01N2800/5020130101 ,  G01N2800/5220130101

公开(公告)号：EP4374168A1

公开(公告)日：2024-05-29

申请号：EP22846618.1

申请日：2022-07-21

Applicant: Creatv Microtech, Inc.

Inventor： ADAMS, Daniel L. ,  TANG, Cha-Mei

IPC: G01N33/483 ,  G01N33/574 ,  G01N33/569

CPC classification number: G01N2800/5220130101 ,  G01N33/5091 ,  G01N33/57492 ,  G01N33/57484 ,  G01N2333/7059620130101 ,  G01N2333/7058920130101 ,  G01N2333/7053220130101 ,  G01N2333/7055320130101 ,  G01N2333/474220130101