公开(公告)号：ES2102505T3

公开(公告)日：1997-08-01

申请号：ES92911242

申请日：1992-04-29

Applicant: DADE MICROSCAN INC

Inventor： JOHNSTON JUDITH ,  FELLAND TRACY ,  BASCOMB SHOSHANA ,  GODSEY JAMES H

IPC: C12Q1/18 ,  C12Q1/02 ,  C12Q1/20 ,  C12N1/38 ,  C12Q1/34

Abstract: In an assay for determination of beta-lactam antibiotic resistance in a target bacterial strain, the strain is grown in the presence of both a beta-lactamese inducing antibiotic and a beta-lactam indicator antibiotic [which kills or inhibits the growth of bacteria] unable to hydrolyze beta-lactam antibiotics. Growth, indicative of drug resistance in the target strain, is monitored by detecting a fluorophor released by the enzymatic cleavage of a metabolizable fluorogenic compound.

公开(公告)号：AU6467098A

公开(公告)日：1998-10-30

申请号：AU6467098

申请日：1998-03-16

Applicant: DADE MICROSCAN INC

Inventor： GODSEY JAMES H ,  NOTHAFT DANIEL M

IPC: C12Q1/04 ,  C12Q1/00

公开(公告)号：CA2257609A1

公开(公告)日：1998-10-15

申请号：CA2257609

申请日：1998-03-16

Applicant: DADE MICROSCAN INC

Inventor： GODSEY JAMES H ,  NOTHAFT DANIEL M

IPC: C12Q1/04 ,  C12Q1/34 ,  C12M1/40 ,  C12Q1/527 ,  C12Q1/58

Abstract: The present invention relates to universal test systems and methods of use thereof for identifying a microorganism among at least two groups of widely divergent microorganisms. The universal test system comprises a predetermined combination of non-redundant biochemical tests comprising a substrate for at least one enzyme wherein the substrate, if acted on by the enzyme results in formation of a detectable product. Detectable products from the combination of biochemical tests are then used to identify the microorganism.

公开(公告)号：AU4752402A

公开(公告)日：2002-08-01

申请号：AU4752402

申请日：2002-06-11

Applicant: DADE MICROSCAN INC

Inventor： GODSEY JAMES H ,  NOTHAFT DANIEL M

IPC: C12Q1/00

公开(公告)号：AT153702T

公开(公告)日：1997-06-15

申请号：AT92911242

申请日：1992-04-29

Applicant: DADE MICROSCAN INC

Inventor： JOHNSTON JUDITH ,  FELLAND TRACY ,  BASCOMB SHOSHANA ,  GODSEY JAMES H

IPC: C12Q1/18 ,  C12Q1/02 ,  C12Q1/20 ,  C12N1/38 ,  C12Q1/34

Abstract: In an assay for determination of beta-lactam antibiotic resistance in a target bacterial strain, the strain is grown in the presence of both a beta-lactamese inducing antibiotic and a beta-lactam indicator antibiotic [which kills or inhibits the growth of bacteria] unable to hydrolyze beta-lactam antibiotics. Growth, indicative of drug resistance in the target strain, is monitored by detecting a fluorophor released by the enzymatic cleavage of a metabolizable fluorogenic compound.