公开(公告)号：MX9306515A

公开(公告)日：1994-04-29

申请号：MX9306515

申请日：1993-10-20

Applicant: DEGUSSA

Inventor： PETSCH HEINRICH ,  WEIGEL HORST ,  HASSEBERG HANS-ALBRECHT ,  HUTHMACHER KLAUS ,  RAUTENBERG STEPHAN

IPC: C07C319/20 ,  C07C323/58 ,  C08F16/34

Abstract: PCT No. PCT/EP93/02838 Sec. 371 Date May 23, 1995 Sec. 102(e) Date May 23, 1995 PCT Filed Oct. 14, 1993 PCT Pub. No. WO94/08957 PCT Pub. Date Apr. 28, 1994The direct saponification of methionine nitrile obtained from methylmercaptopropionaldehyde, prussic acid and ammonia gives low yields, catalyst and educt losses and unwanted side-products. The aim of the invention is therefore to provide a method which can be carried out without isolating the intermediate products, in particular continuously, and with low losses. The ketone used is recovered in high yields after amide saponification since this liberates the ketone from side-products. In order to recover the ammonia, it is necessary for the ammonia to be substantially freed of ketone, the mixture of ammonia, ketone and water obtained being separated under pressure in a separation column. When the amide is saponified at >/=160 DEG C., amide concentrations of less than 25% by wt. are preferred. Methionine nitrile is produced by treatment with at least 4 equivalents of >/=50% by wt. ammonia at between 40 DEG and 80 DEG C./or between 5 and 60 min. Cyanide residues are destroyed by heating to over 150 DEG C. Methionine is of particular use as a feedstuff, in particular in aqueous solution.

公开(公告)号：DE3514938A1

公开(公告)日：1986-10-30

申请号：DE3514938

申请日：1985-04-25

Applicant: DEGUSSA

Inventor： PRESCHER GUENTER DR ,  GRUND ANDREAS DR ,  PETSCH HEINRICH ,  BOEHME GEORG

IPC: B01J31/02 ,  C07B61/00 ,  C07C67/44 ,  C07C69/75

公开(公告)号：SG47910A1

公开(公告)日：1998-04-17

申请号：SG1996005199

申请日：1993-10-14

Applicant: DEGUSSA

Inventor： HASSEBERG HANS-ALBRECHT ,  PETSCH HEINRICH ,  WEIGEL HORST ,  HUTHMACHER KLAUS ,  RAUTENBERG STEPHAN

IPC: C07C319/20 ,  C07C323/58

Abstract: PCT No. PCT/EP93/02838 Sec. 371 Date May 23, 1995 Sec. 102(e) Date May 23, 1995 PCT Filed Oct. 14, 1993 PCT Pub. No. WO94/08957 PCT Pub. Date Apr. 28, 1994The direct saponification of methionine nitrile obtained from methylmercaptopropionaldehyde, prussic acid and ammonia gives low yields, catalyst and educt losses and unwanted side-products. The aim of the invention is therefore to provide a method which can be carried out without isolating the intermediate products, in particular continuously, and with low losses. The ketone used is recovered in high yields after amide saponification since this liberates the ketone from side-products. In order to recover the ammonia, it is necessary for the ammonia to be substantially freed of ketone, the mixture of ammonia, ketone and water obtained being separated under pressure in a separation column. When the amide is saponified at >/=160 DEG C., amide concentrations of less than 25% by wt. are preferred. Methionine nitrile is produced by treatment with at least 4 equivalents of >/=50% by wt. ammonia at between 40 DEG and 80 DEG C./or between 5 and 60 min. Cyanide residues are destroyed by heating to over 150 DEG C. Methionine is of particular use as a feedstuff, in particular in aqueous solution.

公开(公告)号：AU675989B2

公开(公告)日：1997-02-27

申请号：AU5333994

申请日：1993-10-14

Applicant: DEGUSSA

Inventor： HASSEBERG HANS-ALBRECHT ,  HUTHMACHER KLAUS ,  RAUTENBERG STEPHAN ,  PETSCH HEINRICH ,  WEIGEL HORST

IPC: C07C319/20 ,  C07C323/58 ,  C07C323/60 ,  C07C227/18

Abstract: PCT No. PCT/EP93/02838 Sec. 371 Date May 23, 1995 Sec. 102(e) Date May 23, 1995 PCT Filed Oct. 14, 1993 PCT Pub. No. WO94/08957 PCT Pub. Date Apr. 28, 1994The direct saponification of methionine nitrile obtained from methylmercaptopropionaldehyde, prussic acid and ammonia gives low yields, catalyst and educt losses and unwanted side-products. The aim of the invention is therefore to provide a method which can be carried out without isolating the intermediate products, in particular continuously, and with low losses. The ketone used is recovered in high yields after amide saponification since this liberates the ketone from side-products. In order to recover the ammonia, it is necessary for the ammonia to be substantially freed of ketone, the mixture of ammonia, ketone and water obtained being separated under pressure in a separation column. When the amide is saponified at >/=160 DEG C., amide concentrations of less than 25% by wt. are preferred. Methionine nitrile is produced by treatment with at least 4 equivalents of >/=50% by wt. ammonia at between 40 DEG and 80 DEG C./or between 5 and 60 min. Cyanide residues are destroyed by heating to over 150 DEG C. Methionine is of particular use as a feedstuff, in particular in aqueous solution.

公开(公告)号：DE4235295A1

公开(公告)日：1994-04-21

申请号：DE4235295

申请日：1992-10-20

Applicant: DEGUSSA

Inventor： HASSEBERG HANS-ALBRECHT DR ,  HUTHMACHER KLAUS DR ,  RAUTENBERG STEPHAN DR ,  PETSCH HEINRICH ,  WEIGEL HORST

IPC: C07C319/20 ,  C07C323/58

Abstract: The direct saponification of methionine nitrile obtained from methylmercaptopropionaldehyde, prussic acid and ammonia gives low yields, catalyst and educt losses and unwanted side-products. The aim of the invention is therefore to provide a method which can be carried out without isolating the intermediate products, in particular continuously, and with low losses. The ketone used is recovered in high yields after amide saponification since this liberates the ketone from side-products. In order to recover the ammonia, it is necessary for the ammonia to be substantially freed of ketone, the mixture of ammonia, ketone and water obtained being separated under pressure in a separation column. When the amide is saponified at >/= 160 DEG C, amide concentrations of less than 25 % by wt. are preferred. Methionine nitrile is produced by treatment with at least 4 equivalents of >/= 50 % by wt. ammonia at between 40 and 80 DEG C for between 5 and 60 min. Cyanide residues are destroyed by heating to over 150 DEG C. Methionine is of particular use as a feedstuff, in particular in aqueous solution.

公开(公告)号：CZ9500947A3

公开(公告)日：1995-09-13

申请号：CZ94795

申请日：1993-10-14

Applicant: DEGUSSA

Inventor： HASSEBERG HANS-ALBRECH DR ,  HUTHMACHER KLAUS DR ,  RAUTENBERG STEPHAN DR ,  PETSCH HEINRICH ,  WEIGEL HORST

IPC: C07C319/20 ,  C07C323/58

CPC classification number: C07C319/20 ,  C07C323/58

公开(公告)号：CZ94795A3

公开(公告)日：1995-09-13

申请号：CZ94795

申请日：1993-10-14

Applicant: DEGUSSA

Inventor： HASSEBERG HANS-ALBRECH DR ,  HUTHMACHER KLAUS DR ,  RAUTENBERG STEPHAN DR ,  PETSCH HEINRICH ,  WEIGEL HORST

IPC: C07C319/20 ,  C07C323/58

Abstract: PCT No. PCT/EP93/02838 Sec. 371 Date May 23, 1995 Sec. 102(e) Date May 23, 1995 PCT Filed Oct. 14, 1993 PCT Pub. No. WO94/08957 PCT Pub. Date Apr. 28, 1994The direct saponification of methionine nitrile obtained from methylmercaptopropionaldehyde, prussic acid and ammonia gives low yields, catalyst and educt losses and unwanted side-products. The aim of the invention is therefore to provide a method which can be carried out without isolating the intermediate products, in particular continuously, and with low losses. The ketone used is recovered in high yields after amide saponification since this liberates the ketone from side-products. In order to recover the ammonia, it is necessary for the ammonia to be substantially freed of ketone, the mixture of ammonia, ketone and water obtained being separated under pressure in a separation column. When the amide is saponified at >/=160 DEG C., amide concentrations of less than 25% by wt. are preferred. Methionine nitrile is produced by treatment with at least 4 equivalents of >/=50% by wt. ammonia at between 40 DEG and 80 DEG C./or between 5 and 60 min. Cyanide residues are destroyed by heating to over 150 DEG C. Methionine is of particular use as a feedstuff, in particular in aqueous solution.

公开(公告)号：AU5333994A

公开(公告)日：1994-05-09

申请号：AU5333994

申请日：1993-10-14

Applicant: DEGUSSA

Inventor： HASSEBERG HANS-ALBRECHT ,  HUTHMACHER KLAUS ,  RAUTENBERG STEPHAN ,  PETSCH HEINRICH ,  WEIGEL HORST

IPC: C07C319/20 ,  C07C323/58

Abstract: PCT No. PCT/EP93/02838 Sec. 371 Date May 23, 1995 Sec. 102(e) Date May 23, 1995 PCT Filed Oct. 14, 1993 PCT Pub. No. WO94/08957 PCT Pub. Date Apr. 28, 1994The direct saponification of methionine nitrile obtained from methylmercaptopropionaldehyde, prussic acid and ammonia gives low yields, catalyst and educt losses and unwanted side-products. The aim of the invention is therefore to provide a method which can be carried out without isolating the intermediate products, in particular continuously, and with low losses. The ketone used is recovered in high yields after amide saponification since this liberates the ketone from side-products. In order to recover the ammonia, it is necessary for the ammonia to be substantially freed of ketone, the mixture of ammonia, ketone and water obtained being separated under pressure in a separation column. When the amide is saponified at >/=160 DEG C., amide concentrations of less than 25% by wt. are preferred. Methionine nitrile is produced by treatment with at least 4 equivalents of >/=50% by wt. ammonia at between 40 DEG and 80 DEG C./or between 5 and 60 min. Cyanide residues are destroyed by heating to over 150 DEG C. Methionine is of particular use as a feedstuff, in particular in aqueous solution.

公开(公告)号：IN180259B

公开(公告)日：1998-01-17

申请号：IN622CA1993

申请日：1993-10-18

Applicant: DEGUSSA

Inventor： HASSEBERG HANS-ALBRECHT ,  HUTHMACHER KLAUS ,  RAUTENBERG STEPHAN ,  PETSCH HEINRICH ,  WEIGEL HORST

IPC: C07C101/02

公开(公告)号：ES2102686T3

公开(公告)日：1997-08-01

申请号：ES93923467

申请日：1993-10-14

Applicant: DEGUSSA

Inventor： HASSEBERG HANS-ALBRECHT ,  HUTHMACHER KLAUS ,  RAUTENBERG STEPHAN ,  PETSCH HEINRICH ,  WEIGEL HORST

IPC: C07C319/20 ,  C07C323/58

Abstract: PCT No. PCT/EP93/02838 Sec. 371 Date May 23, 1995 Sec. 102(e) Date May 23, 1995 PCT Filed Oct. 14, 1993 PCT Pub. No. WO94/08957 PCT Pub. Date Apr. 28, 1994The direct saponification of methionine nitrile obtained from methylmercaptopropionaldehyde, prussic acid and ammonia gives low yields, catalyst and educt losses and unwanted side-products. The aim of the invention is therefore to provide a method which can be carried out without isolating the intermediate products, in particular continuously, and with low losses. The ketone used is recovered in high yields after amide saponification since this liberates the ketone from side-products. In order to recover the ammonia, it is necessary for the ammonia to be substantially freed of ketone, the mixture of ammonia, ketone and water obtained being separated under pressure in a separation column. When the amide is saponified at >/=160 DEG C., amide concentrations of less than 25% by wt. are preferred. Methionine nitrile is produced by treatment with at least 4 equivalents of >/=50% by wt. ammonia at between 40 DEG and 80 DEG C./or between 5 and 60 min. Cyanide residues are destroyed by heating to over 150 DEG C. Methionine is of particular use as a feedstuff, in particular in aqueous solution.