公开(公告)号：DE1159464B

公开(公告)日：1963-12-19

申请号：DED0036533

申请日：1961-07-12

Applicant: DEGUSSA

Inventor： BESCHKE HELMUT ,  SCHULER DR WILHELM A

IPC: C07D417/06 ,  C07D513/04

公开(公告)号：DE1160442B

公开(公告)日：1964-01-02

申请号：DED0034117

申请日：1960-02-18

Applicant: DEGUSSA

Inventor： SCHULER DR WILHELM A ,  BESCHKE HELMUT ,  SCHLICHTEGROLL DR ANSGAR V

IPC: C07D417/06 ,  C07D513/04

Abstract: The invention comprises compounds of the general formula (wherein R1 represents hydrogen, chlorine, bromine or a trihalomethyl group, Alk represents a straight or branched alkylene chain of 1-4 carbon atoms, and R2 represents a C1-4 alkyl group or a hydroxyalkyl or acyloxyalkyl group) and their acid addition salts, and the preparation thereof by reacting an appropriate 10-unsubstituted phenthiazine or azaphenthiazine with a compound of the general formula (wherein Hal represents a halogen atom), or reacting a compound of the general formula with a compound of the general formula at elevated temperature, or reacting a compound of the general formula at elevated temperature with a C1-4 alkyl ester, a haloalcohol or an acylated haloalcohol, and in either case, if desired, converting the resulting bases into acid addition salts. The products have anti-emetic and sedative properties.

公开(公告)号：DE1014544B

公开(公告)日：1957-08-29

申请号：DED0022943

申请日：1956-05-12

Applicant: DEGUSSA

Inventor： SCHULER DR WILHELM A ,  KLEBE DR HANS

IPC: C07D513/04