公开(公告)号：WO0173431A3

公开(公告)日：2002-07-04

申请号：PCT/US0107311

申请日：2001-03-06

Applicant: DELSYS PHARMACEUTICAL CORP

Inventor： LOEWY ZVI ,  MATTHIES DENNIS LEE

IPC: G01N33/50 ,  A61J1/03 ,  A61J3/00 ,  A61K9/22 ,  A61K9/52 ,  A61K9/70 ,  B05B5/08 ,  B65B1/04 ,  B65B1/30 ,  B65B11/50 ,  G01N33/52 ,  G01N33/543

CPC classification number: A61J3/00 ,  A61J1/035 ,  A61K9/70 ,  B05B5/08 ,  B65B1/04 ,  B65B1/30 ,  B65B11/50 ,  G01N33/521 ,  G01N33/54386

Abstract: The present invention provides an integrated structural unit that includes a diagnostic form that includes at least one active ingredient that is present in an amount that advantageously does not vary by more than about five percent from a predetermined target amount. In one embodiment, the unit form comprises a substrate, a deposit that is disposed on the substrate, and a spreading layer that overlies the deposit and is used to retain and spread a sample of liquid which is to be assayed. The deposit comprises a powder, including the active ingredient(s). The diagnostic form is created via a dry powder deposition apparatus that electrostatically deposits the powder on the substrate utilizing an electrostatic chuck and charged powder delivery apparatus.

Abstract translation: 本发明提供了一种综合结构单元，其包括诊断形式，其包括至少一种活性成分，所述活性成分的存在量有利地不超过预定目标量的约5％。 在一个实施例中，单元形式包括衬底，设置在衬底上的沉积物和覆盖在沉积物上并用于保留和铺展待测定的液体样品的铺展层。 沉积物包含包含活性成分的粉末。 通过使用静电卡盘和带电粉末输送装置将粉末静电沉积在基底上的干粉沉积装置产生诊断形式。

公开(公告)号：CA2382089A1

公开(公告)日：2001-10-04

申请号：CA2382089

申请日：2001-03-06

Applicant: DELSYS PHARMACEUTICAL CORP

Inventor： LOEWY ZVI ,  MATTHIES DENNIS LEE

IPC: G01N33/50 ,  A61J1/03 ,  A61J3/00 ,  A61K9/22 ,  A61K9/52 ,  A61K9/70 ,  B05B5/08 ,  B65B1/04 ,  B65B1/30 ,  B65B11/50 ,  G01N33/52 ,  G01N33/543

Abstract: The present invention provides an integrated structural unit that includes a diagnostic form that includes at least one active ingredient that is present in an amount that advantageously does not vary by more than about five perce nt from a predetermined target amount. In one embodiment, the unit form compris es a substrate, a deposit that is disposed on the substrate, and a spreading layer that overlies the deposit and is used to retain and spread a sample of liquid which is to be assayed. The deposit comprises a powder, including the active ingredient(s). The diagnostic form is created via a dry powder deposition apparatus that electrostatically deposits the powder on the substrate utilizing an electrostatic chuck and charged powder delivery apparatus.

公开(公告)号：NZ517303A

公开(公告)日：2004-02-27

申请号：NZ51730301

申请日：2001-03-06

Applicant: DELSYS PHARMACEUTICAL CORP

Inventor： LOEWY ZVI ,  MATTHIES DENNIS LEE

IPC: G01N33/50 ,  A61J1/03 ,  A61J3/00 ,  A61K9/22 ,  A61K9/52 ,  A61K9/70 ,  B05B5/08 ,  B65B1/04 ,  B65B1/30 ,  B65B11/50 ,  G01N33/52 ,  G01N33/543

Abstract: An integrated structural unit that includes a diagnostic form that includes at least one active ingredient that is present in an amount that advantageously does not vary by more than about five percent from a predetermined target amount is disclosed, wherein the diagnostic unit form comprises a substrate, a deposit that is disposed on the substrate, and a spreading layer that overlies the deposit and is used to retain and spread a sample of liquid which is to be assayed. The deposit comprises a powder, including the active ingredient(s). The diagnostic form is created via a dry powder deposition apparatus that electrostatically deposits the powder on the substrate utilizing an electrostatic chuck and charged powder delivery apparatus.

公开(公告)号：HU0204499A2

公开(公告)日：2003-06-28

申请号：HU0204499

申请日：2001-03-06

Applicant: DELSYS PHARMACEUTICAL CORP

Inventor： LOEWY ZVI ,  MATTHIES DENNIS LEE

IPC: G01N33/50 ,  A61J1/03 ,  A61J3/00 ,  A61K9/22 ,  A61K9/52 ,  A61K9/70 ,  B05B5/08 ,  B65B1/04 ,  B65B1/30 ,  B65B11/50 ,  G01N33/52 ,  G01N33/543

Abstract: The present invention provides an integrated structural unit that includes a diagnostic form that includes at least one active ingredient that is present in an amount that advantageously does not vary by more than about five percent from a predetermined target amount. In one embodiment, the unit form comprises a substrate, a deposit that is disposed on the substrate, and a spreading layer that overlies the deposit and is used to retain and spread a sample of liquid which is to be assayed. The deposit comprises a powder, including the active ingredient(s). The diagnostic form is created via a dry powder deposition apparatus that electrostatically deposits the powder on the substrate utilizing an electrostatic chuck and charged powder delivery apparatus.

公开(公告)号：AU4201701A

公开(公告)日：2001-10-08

申请号：AU4201701

申请日：2001-03-06

Applicant: DELSYS PHARMACEUTICAL CORP

Inventor： LOEWY ZVI ,  MATTHIES DENNIS LEE

IPC: G01N33/50 ,  A61J1/03 ,  A61J3/00 ,  A61K9/22 ,  A61K9/52 ,  A61K9/70 ,  B05B5/08 ,  B65B1/04 ,  B65B1/30 ,  B65B11/50 ,  G01N33/52 ,  G01N33/543

Abstract: The present invention provides an integrated structural unit that includes a diagnostic form that includes at least one active ingredient that is present in an amount that advantageously does not vary by more than about five percent from a predetermined target amount. In one embodiment, the unit form comprises a substrate, a deposit that is disposed on the substrate, and a spreading layer that overlies the deposit and is used to retain and spread a sample of liquid which is to be assayed. The deposit comprises a powder, including the active ingredient(s). The diagnostic form is created via a dry powder deposition apparatus that electrostatically deposits the powder on the substrate utilizing an electrostatic chuck and charged powder delivery apparatus.