公开(公告)号：CA2205570A1

公开(公告)日：1997-04-03

申请号：CA2205570

申请日：1996-09-19

Applicant: DIONEX CORP

Inventor： RECKNOR MICHAEL WILLIAM ,  WOLZE DAVID A

IPC: G01N1/00 ,  G01N1/14 ,  G01N27/447

Abstract: A present invention and method provides a pressure injection apparatus (20) that injects a quantitatively defined volume of liquid sample (21) from a container (22) into a capillary device (23). A servo pressure primary regulator (26) is included which precisely regulates the fluid from a supply pressure (PS) to a substantially constant regulated pressure (PR) in communication with the liquid sample (21) for a predetermined period of time. A feedback mechanism cooperates with a valving assembly (31) to continuously monitor and adjust the regulated pressure (PR) to be substantially constant and precise for delivery to the container (21).

公开(公告)号：AU7076596A

公开(公告)日：1997-04-17

申请号：AU7076596

申请日：1996-09-19

Applicant: DIONEX CORP

Inventor： RECKNOR MICHAEL W ,  WOLZE DAVID A

IPC: G01N1/00 ,  G01N1/14 ,  G01N27/447 ,  G01N27/26

Abstract: A present invention and method provides a pressure injection apparatus (20) that injects a quantitatively defined volume of liquid sample (21) from a container (22) into a capillary device (23). A servo pressure primary regulator (26) is included which precisely regulates the fluid from a supply pressure (PS) to a substantially constant regulated pressure (PR) in communication with the liquid sample (21) for a predetermined period of time. A feedback mechanism cooperates with a valving assembly (31) to continuously monitor and adjust the regulated pressure (PR) to be substantially constant and precise for delivery to the container (21).

公开(公告)号：EP0805975A4

公开(公告)日：1998-12-23

申请号：EP96931652

申请日：1996-09-19

Applicant: DIONEX CORP

Inventor： RECKNOR MICHAEL W ,  WOLZE DAVID A

IPC: G01N1/00 ,  G01N1/14 ,  G01N27/447 ,  G01N27/26

CPC classification number: G01N27/44743

Abstract: A present invention and method provides a pressure injection apparatus (20) that injects a quantitatively defined volume of liquid sample (21) from a container (22) into a capillary device (23). A servo pressure primary regulator (26) is included which precisely regulates the fluid from a supply pressure (PS) to a substantially constant regulated pressure (PR) in communication with the liquid sample (21) for a predetermined period of time. A feedback mechanism cooperates with a valving assembly (31) to continuously monitor and adjust the regulated pressure (PR) to be substantially constant and precise for delivery to the container (21).

公开(公告)号：AU692597B2

公开(公告)日：1998-06-11

申请号：AU3403895

申请日：1995-08-02

Applicant: DIONEX CORP

Inventor： WOLZE DAVID A

IPC: G01N30/34 ,  F04B49/06 ,  F04B49/08 ,  F04B49/20 ,  G01N30/32 ,  G05B13/02 ,  G05D7/06 ,  G06F19/00 ,  B01D15/08

Abstract: Flowrate in a precision pump used for liquid chromatography employs a digital control system incorporating artificial intelligence. The pump system operates in a default flow mode, wherein real-time pressure feedback is not used to control motor speed, or in pressure mode, wherein motor speed is controlled by the pump system pressure point. The artificial intelligence commands mode changes to pressure mode when the constant displacement flow measurement time is within a threshold relative to commanded flowrate, and when the higher pressure piston is being measured. Flow mode pressure ripple is minimized by monitoring pressure points and commanding motor speed change at appropriate positions during the motor cam rotation. Pressure mode uses the higher pressurized piston as a reference for constant displacement flow measurement and provides accurate flowrate even if one piston is leaky. In pressure mode, the artificial intelligence monitors for intake cycle oscillation and optimizes a highest system pressure gain dynamically. By determining the duration of hydraulic intake and activating proportioning only during the constant intake flow portion of an intake cycle, constant flowrate proportioning is provided. The present invention compensates for a variety of system and environmental variables including leaky valves, air bubbles, a leaky cylinder head, pressure changes, and variations in anticipated compliance and can maintain a flowrate constant within about +/-1% without using real-time pressure feedback.

公开(公告)号：AU3403895A

公开(公告)日：1996-03-22

申请号：AU3403895

申请日：1995-08-02

Applicant: DIONEX CORP

Inventor： WOLZE DAVID A

IPC: G01N30/34 ,  F04B49/06 ,  F04B49/08 ,  F04B49/20 ,  G01N30/32 ,  G05B13/02 ,  G05D7/06 ,  G06F19/00 ,  B01D15/08

Abstract: Flowrate in a precision pump used for liquid chromatography employs a digital control system incorporating artificial intelligence. The pump system operates in a default flow mode, wherein real-time pressure feedback is not used to control motor speed, or in pressure mode, wherein motor speed is controlled by the pump system pressure point. The artificial intelligence commands mode changes to pressure mode when the constant displacement flow measurement time is within a threshold relative to commanded flowrate, and when the higher pressure piston is being measured. Flow mode pressure ripple is minimized by monitoring pressure points and commanding motor speed change at appropriate positions during the motor cam rotation. Pressure mode uses the higher pressurized piston as a reference for constant displacement flow measurement and provides accurate flowrate even if one piston is leaky. In pressure mode, the artificial intelligence monitors for intake cycle oscillation and optimizes a highest system pressure gain dynamically. By determining the duration of hydraulic intake and activating proportioning only during the constant intake flow portion of an intake cycle, constant flowrate proportioning is provided. The present invention compensates for a variety of system and environmental variables including leaky valves, air bubbles, a leaky cylinder head, pressure changes, and variations in anticipated compliance and can maintain a flowrate constant within about +/-1% without using real-time pressure feedback.

公开(公告)号：EP0777887A4

公开(公告)日：1998-12-02

申请号：EP95930788

申请日：1995-08-02

Applicant: DIONEX CORP

Inventor： WOLZE DAVID A

IPC: G01N30/34 ,  F04B49/06 ,  F04B49/08 ,  F04B49/20 ,  G01N30/32 ,  G05B13/02 ,  G05D7/06 ,  G06F19/00 ,  B01D15/08

CPC classification number: G05D7/0682 ,  F04B49/065 ,  F04B49/20 ,  F04B2201/0803 ,  F04B2205/05 ,  F04B2205/09 ,  F04B2207/041 ,  F04B2207/042 ,  G01N30/32 ,  G01N2030/324 ,  G01N2030/326

Abstract: Flowrate in a liquid chromatography precision pump (100) employs a digital control system (128) with artificial intelligence (150). In a default flow mode, pump motor speed is controlled without using real-time pressure feedback, which speed in a pressure mode is controlled using the pump system pressure point. Pressure mode is commanded by the artificial intelligence (150) when constant displacement flow measurement time is within a desired threshold and when the higher pressure piston (34a or 34B), which is used as a constant displacement flow measurement reference, is being measured. Flow mode pressure ripple is minimized by monitoring pressure points and commanding motor (18) speed change at appropriate rotation positions of a motor shaft (24) mounted cam. In pressure mode, the artificial intelligence (150) monitors for intake cycle oscillation and optimizes a highest system pressure gain dynamically. Constant flowrate proportion is provided by activating proportioning only during a constant intake flow portion of an intake cycle.

公开(公告)号：CA2205570C

公开(公告)日：2000-02-01

申请号：CA2205570

申请日：1996-09-19

Applicant: DIONEX CORP

Inventor： WOLZE DAVID A ,  RECKNOR MICHAEL WILLIAM

IPC: G01N1/00 ,  G01N1/14 ,  G01N27/447

Abstract: A present invention and method provides a pressure injection apparatus (20) that injects a quantitatively defined volume of liquid sample (21) from a container (22) into a capillary device (23). A servo pressure primary regulator (26) is included which precisely regulates the fluid from a supply pressure (PS) to a substantially constant regulated pressure (PR) in communication with the liquid sample (21) for a predetermined period of time. A feedback mechanism cooperates with a valving assembly (31) to continuously monitor and adjust the regulated pressure (PR) to be substantially constant and precise for delivery to the container (21).

公开(公告)号：CA2198907C

公开(公告)日：2000-02-01

申请号：CA2198907

申请日：1995-08-02

Applicant: DIONEX CORP

Inventor： WOLZE DAVID A

IPC: G01N30/34 ,  F04B49/06 ,  F04B49/08 ,  F04B49/20 ,  G01N30/32 ,  G05B13/02 ,  G05D7/06 ,  G06F19/00 ,  B01D15/08

Abstract: Flowrate in a liquid chromatography precision pump (100) employs a digital control system (128) with artificial intelligence (150). In a default flow mode, pump motor speed is controlled without using real-time pressure feedback, which speed in a pressure mode is controlled using the pump system pressure point. Pressure mode is commanded by the artificial intelligence (150) when constant displacement flow measurement time is within a desired threshold and when the higher pressure piston (34a or 34B), which is used as a constant displacement flow measurement reference, is being measured. Flow mode pressure ripple is minimized by monitoring pressure points and commanding motor (18) speed change at appropriate rotation positions of a motor shaft (24) mounted cam. In pressure mode, the artificial intelligence (150) monitors for intake cycle oscillation and optimizes a highest system pressure gain dynamically. Constant flowrate proportion is provided by activating proportioning only during a constant intake flow portion of an intake cycle.

公开(公告)号：CA2198907A1

公开(公告)日：1996-03-07

申请号：CA2198907

申请日：1995-08-02

Applicant: DIONEX CORP

Inventor： WOLZE DAVID A

IPC: G01N30/34 ,  F04B49/06 ,  F04B49/08 ,  F04B49/20 ,  G01N30/32 ,  G05B13/02 ,  G05D7/06 ,  G06F19/00 ,  B01D15/08

Abstract: Flowrate in a precision pump used for liquid chromatography employs a digital control system incorporating artificial intelligence. The pump system operates in a default flow mode, wherein real-time pressure feedback is not used to control motor speed, or in pressure mode, wherein motor speed is controlled by the pump system pressure point. The artificial intelligence commands mode changes to pressure mode when the constant displacement flow measurement time is within a threshold relative to commanded flowrate, and when the higher pressure piston is being measured. Flow mode pressure ripple is minimized by monitoring pressure points and commanding motor speed change at appropriate positions during the motor cam rotation. Pressure mode uses the higher pressurized piston as a reference for constant displacement flow measurement and provides accurate flowrate even if one piston is leaky. In pressure mode, the artificial intelligence monitors for intake cycle oscillation and optimizes a highest system pressure gain dynamically. By determining the duration of hydraulic intake and activating proportioning only during the constant intake flow portion of an intake cycle, constant flowrate proportioning is provided. The present invention compensates for a variety of system and environmental variables including leaky valves, air bubbles, a leaky cylinder head, pressure changes, and variations in anticipated compliance and can maintain a flowrate constant within about +/-1% without using real-time pressure feedback.