中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

44 records (took 0.028 seconds)

    Sulfonamide based anion exchange resins
    1.
    发明授权
    Sulfonamide based anion exchange resins 有权

    公开(公告)号：US12285704B2

    公开(公告)日：2025-04-29

    申请号：US17354058

    申请日：2021-06-22

    Applicant: Dionex Corporation ,  Melvin Hatch

    Inventor： Melvin Hatch ,  Christopher A. Pohl ,  Manikandan Jayaraman

    IPC: B01D15/36 ,  B01J41/05 ,  B01J41/13 ,  B01J41/14 ,  B01J41/20

    Abstract: An ion exchange resin for use as a stationary phase in an ion chromatography column. The ion exchange resin has a negatively charged substrate particle, a positively charged polymer layer bound to the negatively charged substrate particle, a linker, and an ion exchange group. The ion exchange group includes a sulfonamide group and an amine, in which the ion exchange group is coupled to the positively charged polymer layer via the linker. When the sulfonamide is in a neutral form, a positively charged amine group provides retention; while when the sulfonamide is in an anionic form, the sulfonamide anion becomes a counter ion to the positively charged amine group, forming a zwitterion that reduces retention at that site. Accordingly, the retention time is able to be controlled by adjusting the mobile phase pH.

    COATED POLY-OLEFINS
    2.
    发明申请
    COATED POLY-OLEFINS 有权

    公开(公告)号：US20220315720A1

    公开(公告)日：2022-10-06

    申请号：US17559830

    申请日：2021-12-22

    Applicant: DIONEX CORPORATION

    Inventor： John M. Riviello ,  Christopher A. Pohl

    IPC: C08J7/04

    Abstract: A coated substrate that comprises a polyolefin substrate having a functional polymer layer disposed thereon. The polyolefin substrate has a flow through pore structure with a pore size ranging from about 5 microns to about 250 microns. The functional polymer layer has a thickness ranging from about 1 micron to about 20 microns and a layer pore structure having a pore size ranging from about 1 nm to about 100 nm.

    Longitudinal gradient chromatography columns
    5.
    发明授权
    Longitudinal gradient chromatography columns 有权

    公开(公告)号：US11198117B2

    公开(公告)日：2021-12-14

    申请号：US16673881

    申请日：2019-11-04

    Applicant: DIONEX CORPORATION

    Inventor： Christopher A. Pohl

    IPC: B01D15/36 ,  B01J20/28 ,  B01J20/286 ,  B01J41/05 ,  B01J41/07 ,  B01J41/14 ,  B01J41/20 ,  B01J47/022 ,  B01J47/04 ,  G01N30/60 ,  G01N30/96

    Abstract: An ion exchange chromatography column contains an ion exchange stationary phase that includes a charged substrate, a plurality of first particles, and a plurality of second particles. The plurality of first particles each include first ion exchange groups and the first particles are ionically bound to the charged substrate. The plurality of second particles each include second ion exchange groups and the second particles are ionically bound to the charged substrate. The first particles having a first ion exchange group density, and the second particles having a second ion exchange group density. The first ion exchange group density is greater than the second ion exchange group density. The ion exchange chromatography column has a number of zones connected in series where each zone can have a varying level of first ion exchange groups and second ion exchange group from the inlet zone to the outlet zone.

    SULFONAMIDE BASED ANION EXCHANGE RESINS
    6.
    发明申请
    SULFONAMIDE BASED ANION EXCHANGE RESINS 有权

    公开(公告)号：US20210308599A1

    公开(公告)日：2021-10-07

    申请号：US17354058

    申请日：2021-06-22

    Applicant: Melvin Hatch ,  Dionex Corporation

    Inventor： Melvin Hatch ,  Christopher A. Pohl ,  Manikandan Jayaraman

    IPC: B01D15/36 ,  B01J41/13 ,  B01J41/20 ,  B01J41/14 ,  B01J41/05

    Abstract: An ion exchange resin for use as a stationary phase in an ion chromatography column. The ion exchange resin has a negatively charged substrate particle, a positively charged polymer layer bound to the negatively charged substrate particle, a linker, and an ion exchange group. The ion exchange group includes a sulfonamide group and an amine, in which the ion exchange group is coupled to the positively charged polymer layer via the linker. When the sulfonamide is in a neutral form, a positively charged amine group provides retention: while when the sulfonamide is in an anionic form, the sulfonamide anion becomes a counter ion to the positively charged amine group, forming a zwitterion that reduces retention at that site. Accordingly, the retention time is able to be controlled by adjusting the mobile phase pH.

    Method for reducing suppressor noise
    8.
    发明授权
    Method for reducing suppressor noise 有权
    降低抑制噪声的方法

    公开(公告)号：US09400268B2

    公开(公告)日：2016-07-26

    申请号：US14455710

    申请日：2014-08-08

    Applicant: DIONEX CORPORATION

    Inventor： Christopher A. Pohl ,  Kannan Srinivasan ,  Brittany Omphroy

    IPC: G01N30/96 ,  B01D15/36

    CPC classification number: G01N30/96 ,  B01D15/361 ,  G01N2030/965

    Abstract: An electrolytic method for suppressing liquid eluent containing previously separated sample analyte anions, counterions to the sample anions, and non-sample anions suppressible to weak acids in an electrolytic device comprising a housing defining at least a sample stream flow channel and an ion receiving flow-through channel separated by an ion exchange bather. The sample stream flow channel includes an upstream channel portion and a downstream channel portion. A first current is applied across the upstream channel portion for substantially completely suppression. A second current is applied across the downstream channel portion at a magnitude of less than 10% of the magnitude of the first current.

    Abstract translation: 一种用于抑制液体洗脱液的电解方法，其包含预先分离的样品分析物阴离子，对样品阴离子的抗衡离子和在电解装置中可被弱酸抑制的非样品阴离子，该电解装置包括限定至少样品流流动通道和离子接收流动通道的壳体， 通过通道由离子交换器分离。 样本流流通道包括上游通道部分和下游通道部分。 跨越上游通道部分施加第一电流以实质上完全抑制。 第二电流以小于第一电流幅度的10％的幅度跨越下游沟道部分施加。

    Fast startup ion chromatography system and methods
    9.
    发明授权
    Fast startup ion chromatography system and methods 有权

    公开(公告)号：US12130269B2

    公开(公告)日：2024-10-29

    申请号：US17459757

    申请日：2021-08-27

    Applicant: DIONEX CORPORATION

    Inventor： Kannan Srinivasan ,  Mrinal Sengupta ,  Yan Liu ,  Christopher A. Pohl ,  Nebojsa Avdalovic

    IPC: G01N30/96 ,  B01D15/36 ,  G01N30/28

    CPC classification number: G01N30/96 ,  B01D15/362 ,  B01D15/367 ,  G01N2030/285

    Abstract: Systems and methods for inhibiting translocation of ions across ion exchange barriers include an eluent generator having an ion source reservoir with a first electrode, an eluent generation chamber with a second electrode, an ion exchange barrier disposed therebetween, and means for reversing the polarity of a voltage or current applied across the first and second electrodes. A first polarity voltage or current applied across the electrodes generates an electric field that promotes translocation of eluent counter ions from the reservoir across the barrier, where the counter ions combine with eluent ions electrolytically generated in the chamber. By reversing the polarity of the voltage or current across the electrodes, the resulting electric field inhibits translocation of counter ions across the barrier from the reservoir into the chamber. Reverse voltage or current bias reduces counter ion concentration in the resting chamber to prevent exhaustion of ion suppressor capacity during start up.

Patent Agency Ranking