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1.发明申请METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA 审中-公开使用硅烷处理的二氧化硅过滤介质在样品中分离组分的方法
公开(公告)号：WO2005115580A3
公开(公告)日：2009-04-16
申请号：PCT/US2005014069
申请日：2005-04-21
Applicant: GENENCOR INT , DOW CORNING , GIBSON GARY L , HAYES KEITH , HENG MENG H , KOLLAR CSILLA , LANE THOMAS H , REVIS ANTHONY , STEELE LANDON M
Inventor： GIBSON GARY L , HAYES KEITH , HENG MENG H , KOLLAR CSILLA , LANE THOMAS H , REVIS ANTHONY , STEELE LANDON M
CPC classification number: B01J20/3259 , B01D15/361 , B01D15/3804 , B01J20/103 , B01J20/14 , B01J20/286 , B01J20/3204 , B01J20/3242 , B01J20/3244 , B01J20/3257 , B01J2220/4887 , Y10T436/25375
Abstract: The present invention provides methods for separating one or more components of interest from a sample containing particulates and soluble materials. The method comprises the steps of: (a) filtering a sample through silica filter media whose surface silanol groups have been reacted with one or more silanes, and (b) simultaneously capturing particulates and binding a soluble component to the silica filter media. The bound soluble component of interest is subsequently eluted from the silica filter media. In one embodiment of the invention, unwanted soluble materials are captured by the treated silica filter media and desired component of interest is recovered from the flow-through. In another embodiment of the invention, different components of interest are recovered from both the eluate and the flow-through. Preferred treated silica filter media are silane-treated rice hull ash, oat hull ash, or diatomaceous earth.
Abstract translation: 本发明提供了从含有微粒和可溶性材料的样品中分离出一种或多种感兴趣组分的方法。 该方法包括以下步骤：（a）通过其表面硅烷醇基团与一种或多种硅烷反应的二氧化硅过滤介质过滤样品，和（b）同时捕获微粒并将可溶组分结合到二氧化硅过滤介质上。 随后从二氧化硅过滤介质中洗脱所结合的可溶性成分。 在本发明的一个实施方案中，不希望的可溶物质被经处理的二氧化硅过滤介质捕获，并且所需的目的组分从流通中回收。 在本发明的另一个实施方案中，感兴趣的不同成分从洗脱液和流通液中回收。 优选的经处理的二氧化硅过滤介质是硅烷处理的稻壳灰，燕麦壳灰或硅藻土。
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2.发明公开METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA 审中-公开用于分离用硅烷处理的二氧化硅过滤介质中使用的样本的成分
公开(公告)号：EP1737551A4
公开(公告)日：2010-03-24
申请号：EP05780037
申请日：2005-04-21
Applicant: GENENCOR INT , DOW CORNING
Inventor： HAYES KEITH , KOLLAR CSILLA , LANE THOMAS H , REVIS ANTHONY , STEELE LANDON M , GIBSON GARY L , HENG MENG H
CPC classification number: B01J20/3259 , B01D15/361 , B01D15/3804 , B01J20/103 , B01J20/14 , B01J20/286 , B01J20/3204 , B01J20/3242 , B01J20/3244 , B01J20/3257 , B01J2220/4887 , Y10T436/25375
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3.发明公开METHOD OF SEPARATING COMPONENTS IN A SAMPLE USING SILANE-TREATED SILICA FILTER MEDIA 审中-公开方法对于组件的在样品分离与硅烷处理KIESELSûUREFILTERMEDIEN使用
公开(公告)号：EP1545734A4
公开(公告)日：2009-11-11
申请号：EP03776237
申请日：2003-10-01
Applicant: DOW CORNING , GENENCOR INT
Inventor： GIBSON GARY L , HAYES KEITH QUENTIN II , HENG MENG H , KOLLAR CSILLA , LANE THOMAS H , REVIS ANTHONY , STEELE LANDON M
CPC classification number: B01J20/286 , B01D15/32 , B01D15/322 , B01D15/327 , B01D15/36 , B01D15/362 , B01D15/363 , B01J20/103 , B01J20/3204 , B01J20/3242 , B01J20/3257 , B01J20/3259 , Y10T436/255
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公开(公告)号：AU2003284009A8
公开(公告)日：2004-06-07
申请号：AU2003284009
申请日：2003-10-01
Applicant: DOW CORNING , GENENCOR INT
Inventor： GIBSON GARY L , HAYES KEITH QUENTIN II , HENG MENG H , KOLLAR CSILLA , LANE THOMAS H , REVIS ANTHONY , STEELE LANDON M
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公开(公告)号：CA2500466A1
公开(公告)日：2004-05-21
申请号：CA2500466
申请日：2003-10-01
Applicant: DOW CORNING , GENENCOR INT
Inventor： GIBSON GARY L , HAYES KEITH QUENTIN II , KOLLAR CSILLA , REVIS ANTHONY , LANE THOMAS H , HENG MENG H , STEELE LANDON M
Abstract: The present invention provides methods for separating one or more components of interest from a sample containing particulates and soluble materials. The methodcomprises the steps of: (a) filtering a sample through silica filter media whose surfacesilanol groups have reacted with one or more silanes, and (b) simultaneously capturingparticulates and binding a soluble component to the silica filter media. The boundsoluble component of interest is subsequently eluted from the silica filter media. In oneembodiment of the invention, unwanted soluble materials are captured by the treatedsilica filt er media and desired component of interest is recovered from the flow-through. In another embodiment of the invention, different components of interest are recoveredfrom both the eluate and the flow-through. Preferred treated silica filter media aresilane-treated rice hull ash or diatomaceous earth with functional quarternary ammoniumgroup or functional sulphonate group. Particulates suitable for the present invention, forexample, are microorganisms.
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Patent Agency Ranking
公开(公告)号：CA2500466C
公开(公告)日：2013-02-26
申请号：CA2500466
申请日：2003-10-01
Applicant: DOW CORNING , GENENCOR INT
Inventor： GIBSON GARY L , HAYES KEITH QUENTIN II , HENG MENG H , KOLLAR CSILLA , LANE THOMAS H , REVIS ANTHONY , STEELE LANDON M
Abstract: The present invention provides methods for separating one or more componentsof interest from a sample containing particulates and soluble materials. The methodcomprises the steps of: (a) filtering a sample through silica filter media whose surfacesilanol groups have reacted with one or more silanes, and (b) simultaneously capturingparticulates and binding a soluble component to the silica filter media. The boundsoluble component of interest is subsequently eluted from the silica filter media. In oneembodiment of the invention, unwanted soluble materials are captured by the treatedsilica filter media and desired component of interest is recovered from the flow-through. In another embodiment of the invention, different components of interest are recoveredfrom both the eluate and the flow-through. Preferred treated silica filter media aresilane-treated rice hull ash or diatomaceous earth with functional quarternary ammoniumgroup or functional sulphonate group. Particulates suitable for the present invention, forexample, are microorganisms.
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公开(公告)号：WO9718234A3
公开(公告)日：1997-08-28
申请号：PCT/US9618168
申请日：1996-11-13
Applicant: GENENCOR INT
Inventor： BECKMAN ERIC J , GHENCIU ELIADOR G , BECKER NATHANIEL T , STEELE LANDON M
IPC: C12N9/00 , C07K1/14 , C07K14/00 , C07K14/465 , C12N9/56
CPC classification number: C12N9/54 , C07K1/145 , C07K14/465 , Y02P20/544 , Y10S435/814
Abstract: There is provided a process for the extraction of water soluble biomaterials such as enzymes or proteins into carbon dioxide utilizing certain carbon dioxide-soluble surfactants. Also provided are certain carbon dioxide-soluble surfactants useful in the extraction of proteins.
Abstract translation: 提供了利用某些二氧化碳可溶性表面活性剂将水溶性生物材料如酶或蛋白质提取到二氧化碳中的方法。 还提供了可用于提取蛋白质的某些二氧化碳可溶性表面活性剂。 表面活性剂选自氟醚硫酸盐，氟醚聚乙二醇嵌段共聚物，氟代醚官能山梨糖醇和氟醚二硫代氨基甲酸盐螯合物。
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8.发明专利Method of separating component in sample using silane-treated silica filter medium 审中-公开使用硅烷处理的二氧化硅过滤介质在样品中分离组分的方法
公开(公告)号：JP2013049054A
公开(公告)日：2013-03-14
申请号：JP2012194495
申请日：2012-09-04
Applicant: Dow Corning Corp , ダウ・コーニング・コーポレイション
Inventor： GIBSON GARY L , HAYES KEITH , HENG MENG H , KOLLAR CSILLA , LANE THOMAS H , REVIS ANTHONY , STEELE LANDON M
IPC: B01J20/281 , B01D15/08 , B01D15/36 , B01D15/38 , B01D39/06 , B01J20/10 , B01J20/286 , B01J20/32 , G01N1/10
CPC classification number: B01J20/3259 , B01D15/361 , B01D15/3804 , B01J20/103 , B01J20/14 , B01J20/286 , B01J20/3204 , B01J20/3242 , B01J20/3244 , B01J20/3257 , B01J2220/4887 , Y10T436/25375
Abstract: PROBLEM TO BE SOLVED: To provide a method for separating one or more components of interest from a sample.SOLUTION: Rice hull ashes, oat hull ashes, or diatomaceous earth are used as silica filter media whose surface active groups have reacted with one or more silanes by silane treatment. The method comprises the steps of: (a) filtering a sample containing particulates and soluble materials through the treated silica filter media; (b) simultaneously capturing particulates and binding a soluble component of interest to the silica filter media; and (c) eluting the bound soluble component of interest from the silica filter media.
Abstract translation: 待解决的问题：提供从样品中分离一个或多个感兴趣成分的方法。 解决方案：稻壳灰烬，燕麦壳灰，或硅藻土用作二氧化硅过滤介质，其表面活性基团通过硅烷处理与一种或多种硅烷反应。 该方法包括以下步骤：（a）通过处理的二氧化硅过滤介质过滤含有微粒和可溶物质的样品; （b）同时捕获微粒并将感兴趣的可溶性组分结合到二氧化硅过滤介质上; 和（c）从二氧化硅过滤介质中洗脱所关注的结合的可溶组分。 版权所有（C）2013，JPO＆INPIT
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公开(公告)号：NZ324509A
公开(公告)日：2000-01-28
申请号：NZ32450996
申请日：1996-11-13
Applicant: UNIV PITTSBURGH , GENENCOR INT
Inventor： BECKMAN ERIC J , GHENCIU ELIADOR G , BECKER NATHANIEL T , STEELE LANDON M , RUSSELL ALAN J
IPC: C12N9/00 , C07K1/14 , C07K14/00 , C07K14/465 , C12N9/56
Abstract: here is provided a process for the extraction of water soluble biomaterials such as enzymes or proteins into carbon dioxide utilizing certain carbon dioxide-soluble surfactants. Also provided are certain carbon dioxide-soluble surfactants useful in the extraction of proteins.
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公开(公告)号：AU1158597A
公开(公告)日：1997-06-05
申请号：AU1158597
申请日：1996-11-13
Applicant: GENENCOR INT , UNIV PITTSBURGH
Inventor： BECKMAN ERIC J , GHENCIU ELIADOR G , BECKER NATHANIEL T , STEELE LANDON M
IPC: C12N9/00 , C07K1/14 , C07K14/00 , C07K14/465 , C12N9/56
Abstract: There is provided a process for the extraction of water soluble biomaterials such as enzymes or proteins into carbon dioxide utilizing certain carbon dioxide-soluble surfactants. Also provided are certain carbon dioxide-soluble surfactants useful in the extraction of proteins. The surfactants are selected from fluoroether sulfate, fluoroether-polyethylene glycol block copolymer, fluoroether-functional sorbitol, and fluoroether dithiocarbamate chelate.
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