公开(公告)号：CA2546157C

公开(公告)日：2014-07-22

申请号：CA2546157

申请日：2004-11-22

Applicant: DOW GLOBAL TECHNOLGIES INC

Inventor： RETALLACK DIANE M ,  SCHNEIDER JANE C ,  RAMSEIER THOMAS MARTIN

IPC: C07H21/04 ,  C07H7/00 ,  C07H19/00 ,  C07K14/21 ,  C07K14/61 ,  C07K16/00 ,  C07K16/16 ,  C12N1/21 ,  C12N15/10 ,  C12N15/62 ,  C12N15/63 ,  C12N15/64 ,  C12N15/72 ,  C12N15/78

Abstract: Improved methods and prokaryotic expression systems for producing recombinant proteins using Sec-system secretion signal peptides are described using Pseudomonas fluorescens Sec secretion systems. Specific novel Sec-system secretion signal peptides are described, as are fusion proteins and coding sequences for improved secretion of recombinant proteins and peptides.