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1.发明申请公开(公告)号：US20220160804A1
公开(公告)日：2022-05-26
申请号：US17426341
申请日：2020-01-23
Applicant: DSM IP Assets B.V.
Inventor： Igor BENDIK , Bettina BOEHLENDORF , Pascale FUCHS BOSSERT , Hubert Paul HUG , Nathalie RICHARD , Guido WAHL
IPC: A61K36/54 , A61K31/365 , A61K31/355 , A61K31/05 , A61K31/593 , A61K36/81 , A61K31/07 , A61K31/202 , A61P11/00
Abstract: The present invention relates to systemic detoxification and chronic inflammation by using extract fractions of Laurus nobilis, that lead to a decrease of anti-inflammatory markers in human lung cell lines and the activation of the Nrf2 pathway, which is a crucial element in intracellular detoxification pathways, decreases the expression of inflammatory cytokines. Therefore, the extract can be used to reduce the adverse effects of air pollution generally (and especially of particulate air pollution), which includes: cardiovascular problems, respiratory diseases, and chronic inflammation of tissues that come into contact with air borne particles.
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公开(公告)号：US20180362428A1
公开(公告)日：2018-12-20
申请号：US16062463
申请日：2016-12-14
Applicant: DSM IP ASSETS B.V.
Inventor： Igor BENDIK , Piero GEOTTI-BIANCHINI , Marc HEIDL , Eileen JACKSON , Alexander SCHLIFKE-POSCHALKO
CPC classification number: C07C33/486 , A61K8/34 , A61K8/345 , A61K8/67 , A61Q19/08 , C07C29/64 , C07F5/027
Abstract: Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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Patent Agency Ranking
公开(公告)号：US20220257550A1
公开(公告)日：2022-08-18
申请号：US17625295
申请日：2020-06-16
Applicant: DSM IP ASSETS B.V.
Inventor： Igor BENDIK , Hubert Paul HUG , Bernd MUSSLER , Ana TSKEVDIANI
IPC: A61K31/202 , A61K31/192 , A61K31/525 , A61P31/12
Abstract: The present invention relates to a combination of elafibranor with either riboflavin or DHA as antiviral agent. The bacteriophage T4 titer on E. coli that is increased by elafibranor in comparison to an untreated control is reversed by the combination of elafibranor with riboflavin or elafibranor with DHA. Therefore, these combinations decrease adverse side effects of elafibranor on the gut microbiota.
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公开(公告)号：US20220023303A1
公开(公告)日：2022-01-27
申请号：US17311742
申请日：2019-12-09
Applicant: DSM IP Assets B.V.
Inventor： Igor BENDIK , Julia BIRD , Susanne DOLD-HÖRMANSPERGER
Abstract: Riboflavin can have a beneficial effect in supporting bowel health in healthy people. Specifically it can relieve diarrhea or constipation, regulate bowel movement frequency, and regulating bowel movement urgency. The dosage brings the daily intake of riboflavin (consumed by diet and by supplement) above the RDA.
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公开(公告)号：US20200290960A1
公开(公告)日：2020-09-17
申请号：US16061418
申请日：2016-12-14
Applicant: DSM IP ASSETS B.V.
Inventor： Igor BENDIK , Piero GEOTTI-BIANCHINI , Marc HEIDL , Eileen JACKSON , Alexander SCHLIFKE-POSCHALKO
IPC: C07C401/00 , A61K8/34 , A61Q19/08
Abstract: Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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公开(公告)号：US20190290563A1
公开(公告)日：2019-09-26
申请号：US16062279
申请日：2016-12-14
Applicant: DSM IP ASSETS B.V.
Inventor： Igor BENDIK , Piero GEOTTI-BIANCHINI , Marc HEIDL , Eileen JACKSON , Alexander SCHLIFKE-POSCHALKO
Abstract: Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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公开(公告)号：US20190002378A1
公开(公告)日：2019-01-03
申请号：US16061697
申请日：2016-12-14
Applicant: DSM IP ASSETS B.V.
Inventor： Igor BENDIK , Piero GEOTTI-BIANCHINI , Marc HEIDL , Eileen JACKSON , Alexander SCHLIFKE-POSCHALKO
Abstract: Novel biaromatic compounds, which are vitamin D analogs, processes for their preparation and cosmetic, dermatological and pharmaceutical preparations containing one or more of these compounds.
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