公开(公告)号：KR20200130373A

公开(公告)日：2020-11-18

申请号：KR20207028600

申请日：2019-03-13

Applicant: EMD MILLIPORE CORP

Inventor： PEARSONS JEFFREY ,  WOOD AMY ,  KRAUS DAVID

IPC: C12M1/00 ,  C12M3/00

Abstract: 유체를위한접을수 있는용기이며, 내부작동체적부를형성하는가요성물질; 상기접을수 있는용기의작동체적부내에부착되는적어도하나의접을수 있는배플로서, 하나이상의채널을가지며상기하나이상의채널에있는적어도하나의구멍을통해작동체적부로하나이상의유체를전달하는상기적어도하나의배플, 작동체적부로부터유체를배출또는배기하기위한상기용기내의하나이상의채널, 및상기용기의작동체적부내에적어도부분적으로배치되는임펠러조립체를포함하는, 접을수 있는용기.

公开(公告)号：SG11201706318SA

公开(公告)日：2017-09-28

申请号：SG11201706318S

申请日：2016-01-12

Applicant: EMD MILLIPORE CORP

Inventor： PROULX STEPHEN ,  PEARSONS JEFFREY

IPC: G01M3/04

Abstract: A system and method for measuring integrity of flexible containers is disclosed. The system uses a low mass flow transducer to monitor the flow of fluid into the flexible container. Based on this flow rate, the existence of an orifice in the flexible container may be detected. The system also includes a second flow path to the flexible container to allow for faster fill times. Greater flow rates are achieve through the use of a second high mass flow transducer or a calibrated bypass path. These alternate paths allow greater flow rates until the flexible container is determined to be nearly full, at which point all flow passes with the low mass flow transducer.

公开(公告)号：CA2975685A1

公开(公告)日：2016-09-09

申请号：CA2975685

申请日：2016-01-12

Applicant: EMD MILLIPORE CORP

Inventor： PROULX STEPHEN ,  PEARSONS JEFFREY

IPC: G01M3/04

Abstract: A system and method for measuring integrity of flexible containers is disclosed. The system uses a low mass flow transducer to monitor the flow of fluid into the flexible container. Based on this flow rate, the existence of an orifice in the flexible container may be detected. The system also includes a second flow path to the flexible container to allow for faster fill times. Greater flow rates are achieve through the use of a second high mass flow transducer or a calibrated bypass path. These alternate paths allow greater flow rates until the flexible container is determined to be nearly full, at which point all flow passes with the low mass flow transducer.

公开(公告)号：SG11202006950RA

公开(公告)日：2020-08-28

申请号：SG11202006950R

申请日：2019-03-13

Applicant: EMD MILLIPORE CORP

Inventor： PEARSONS JEFFREY ,  WOOD AMY ,  KRAUS DAVID

IPC: C12M1/00 ,  C12M3/00

Abstract: A collapsible container for a fluid that includes a flexible material, defining an internal working volume; at least one collapsible baffle adhered within the working volume of said collapsible container, the at least one baffle having one or more channels for delivering one or more fluids into the working volume via at least one hole in said one or more channels, one or more channels in said container for exiting or venting fluids from the working volume, and an impeller assembly disposed at least partially within said working volume of said container.

公开(公告)号：CA2993564C

公开(公告)日：2019-10-22

申请号：CA2993564

申请日：2014-03-17

Applicant: EMD MILLIPORE CORP

Inventor： DER KARA ,  HANSEN ANNE ,  MCSWEENEY JAMES ,  KRAUS DAVID ,  PEARSONS JEFFREY ,  WOOD AMY

IPC: B01J19/18

Abstract: A container, such as a disposable or single use bioreactor, optionally having one or more inlets and one or more outlets and a mixer associated with the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The container includes a flexible baffle shaped and positioned within the container to improve mixing, particularly to improve low shear mixing. The baffle is positioned within the container so as to disrupt the vortex formed by the mixer, or prevent formation of a vortex. The baffle is shaped with both horizontal and vertical elements to enhance disruption of the vortex across the entire vessel height and provide homogeneous mixing throughout all operating volumes. In certain embodiments, the baffle is X- shaped.

公开(公告)号：CA2993564A1

公开(公告)日：2014-10-23

申请号：CA2993564

申请日：2014-03-17

Applicant: EMD MILLIPORE CORP

Inventor： DER KARA ,  HANSEN ANNE ,  MCSWEENEY JAMES ,  KRAUS DAVID ,  PEARSONS JEFFREY ,  WOOD AMY

IPC: B01J19/18

Abstract: A container, such as a disposable or single use bioreactor, optionally having one or more inlets and one or more outlets and a mixer associated with the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The container includes a flexible baffle shaped and positioned within the container to improve mixing, particularly to improve low shear mixing. The baffle is positioned within the container so as to disrupt the vortex formed by the mixer, or prevent formation of a vortex. The baffle is shaped with both horizontal and vertical elements to enhance disruption of the vortex across the entire vessel height and provide homogeneous mixing throughout all operating volumes. In certain embodiments, the baffle is X- shaped.

公开(公告)号：SG11201508282UA

公开(公告)日：2015-11-27

申请号：SG11201508282U

申请日：2014-03-17

Applicant: EMD MILLIPORE CORP

Inventor： DER KARA ,  HANSEN ANNE ,  MCSWEENEY JAMES ,  KRAUS DAVID ,  PEARSONS JEFFREY ,  WOOD AMY

IPC: B01F7/16

Abstract: A container, such as a disposable or single use bioreactor, optionally having one or more inlets and one or more outlets and a mixer associated with the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The container includes a flexible baffle shaped and positioned within the container to improve mixing, particularly to improve low shear mixing. The baffle is positioned within the container so as to disrupt the vortex formed by the mixer, or prevent formation of a vortex. The baffle is shaped with both horizontal and vertical elements to enhance disruption of the vortex across the entire vessel height and provide homogeneous mixing throughout all operating volumes. In certain embodiments, the baffle is X-shaped.

公开(公告)号：CA2908806A1

公开(公告)日：2014-10-23

申请号：CA2908806

申请日：2014-03-17

Applicant: EMD MILLIPORE CORP

Inventor： DER KARA ,  HANSEN ANNE ,  MCSWEENEY JAMES ,  KRAUS DAVID ,  PEARSONS JEFFREY ,  WOOD AMY

IPC: B01F7/16

Abstract: A container, such as a disposable or single use bioreactor, optionally having one or more inlets and one or more outlets and a mixer associated with the container to cause mixing, dispersing, homogenizing and/or circu1ation of one or more ingredients contained or added to the container. The container includes a flexible baffle shaped and positioned within the container to improve mixing, particularly to improve low shear mixing. The baffle is positioned within the container so as to disrupt the vortex formed by the mixer, or prevent formation of a vortex. The baffle is shaped with both horizontal and vertical elements to enhance disruption of the vortex across the entire vessel height and provide homogeneous mixing throughout all operating volumes. In certain embodiments, the baffle is X- shaped.

公开(公告)号：CA3090847A1

公开(公告)日：2019-10-17

申请号：CA3090847

申请日：2019-03-13

Applicant: EMD MILLIPORE CORP

Inventor： PEARSONS JEFFREY ,  WOOD AMY ,  KRAUS DAVID

IPC: C12M1/00 ,  C12M3/00

Abstract: CA 03090847 2020-08-06 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1 11111 1111111 11 111111 111 11111 11111111 1 1 111 1111111111111 1111 11111 111 11111111111 111 1111 Organization 0-----International Bureau (10) International Publication Number (43) International Publication Date WO 2019/199406 Al 17 October 2019 (17.10.2019) WIPO I PCT (51) International Patent Classification: (74) Agent: MARTINEAU, Eric, J. et al.; c/o EMD MILLI-C12M 1/00 (2006.01) C12M 3/00 (2006.01) PORE CORPORATION, 400 Summit Drive, Burlington, MA 01803 (US). (21) International Application Number: PCT/U52019/022026 (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, (22) International Filing Date: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, 13 March 2019 (13.03.2019) CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, (25) Filing Language: English DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ED, EL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, (26) Publication Language: English KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, (30) Priority Data: MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, 62/655,277 10 April 2018 (10.04.2018) US OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, (71) Applicant: EMD MILLIPORE CORPORATION TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. [US/US]; c/o EMD Millipore Corporation, 400 Summit Dri-ve, Burlington, MA 01803 (US). (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (72) Inventors: PEARSONS, Jeffrey; c/o EMD Millipore Cor-GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, poration, 400 Summit Drive, Burlington, MA 01803 (US). UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, WOOD, Amy; c/o EMD Millipore Corporation, 400 Sum-TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, mit Drive, Burlington, MA 01803 (US). KRAUS, David; c/ EE, ES, FI, FR, GB, GR, HR, HU, EE, IS, IT, LT, LU, LV, o EMD Millipore Corporation, 400 Summit Drive, Burling-MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, . ton, MA 01803 (US). TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, . KM, ML, MR, NE, SN, TD, TG). (54) Title: SINGLE USE CONTAINER INCLUDING A COLLAPSIBLE BAFFLE HAVING CHANNELS (57) Abstract: A collapsible container for a fluid that includes a flexible ma-_ . terial, defining an internal working volume; at least one collapsible baffle ad--50 hered within the working volume of said collapsible container, the at least \---."-*\:\:\ ( 44 ..--- one baffle having one or more channels for delivering one or more fluids into 40 . the working volume via at least one hole in said one or more chamtels, one or . 46 :0\4 \II ,. I 46 more channels in said container for exiting or venting fluids from the work--working volume of said container. \t ing volume, and an impeller assembly disposed at least partially within said L . Fli . ; 714111-1-6111 . ..!_:-....--la 12 i 20 1 bill 10 . 2 I ii 36 38 = 111 18 5 312-- I _ B Il to,''4.11.11 46 28 vir tkzitµ ) =I; 30 0 44 GT GT 22 16 1-1 -...... GT FIG. 1 1-1 0 CI c [Continued on next page] CA 03090847 2020-08-06 WO 2019/199406 Al I IllIl NMI II 1111111111111111 3E111 I II 111 OH IllIl 1111111111111111101111111111111111111 Published: ¨ with international search report (Art. 21(3))

公开(公告)号：CA2908806C

公开(公告)日：2018-04-24

申请号：CA2908806

申请日：2014-03-17

Applicant: EMD MILLIPORE CORP

Inventor： DER KARA ,  HANSEN ANNE ,  MCSWEENEY JAMES ,  KRAUS DAVID ,  PEARSONS JEFFREY ,  WOOD AMY

IPC: B01F7/16 ,  B01F15/00

Abstract: A container, such as a disposable or single use bioreactor, optionally having one or more inlets and one or more outlets and a mixer associated with the container to cause mixing, dispersing, homogenizing and/or circu1ation of one or more ingredients contained or added to the container. The container includes a flexible baffle shaped and positioned within the container to improve mixing, particularly to improve low shear mixing. The baffle is positioned within the container so as to disrupt the vortex formed by the mixer, or prevent formation of a vortex. The baffle is shaped with both horizontal and vertical elements to enhance disruption of the vortex across the entire vessel height and provide homogeneous mixing throughout all operating volumes. In certain embodiments, the baffle is X- shaped.