公开(公告)号：US20240269455A1

公开(公告)日：2024-08-15

申请号：US18411879

申请日：2024-01-12

Applicant: EMD Millipore Corporation

Inventor： Heejin Lee ,  Michael James Susienka ,  John Paul Amara

IPC: A61M39/18 ,  A61M39/14

CPC classification number: A61M39/18 ,  A61M39/14 ,  A61M2205/75

Abstract: A system for sterilizing or bioburden-reducing a filter device includes a breathable microbial barrier, a filter device, and a tubing arrangement. The tubing arrangement may be coupled to at least one opening of the filter device. The tubing arrangement may include an aseptic connector, a sealable component, and a port, all of which are in fluid communication with one another. The sealable component may be disposed in the tubing arrangement between the at least one opening of the filter device and the aseptic connector. The sealable component may be reconfigurable between an open configuration, which facilitates the entry of a sterilization vapor into the tubing arrangement and the filter device when subjected to a sterilization or bioburden reduction process, and a closed configuration, where the tubing arrangement is sealed from a surrounding environment. The breathable microbial barrier may at least partially enclose the port of the tubing arrangement.

公开(公告)号：US20210322901A1

公开(公告)日：2021-10-21

申请号：US17262356

申请日：2019-08-12

Applicant: EMD Millipore Corporation

Inventor： Michael James Susienka ,  Jeremy Perreault ,  Joseph Geringer ,  Brian Hillier ,  Joseph Muldoon ,  John Paul Amara

IPC: B01D27/14 ,  B01D35/30 ,  B01D63/08

Abstract: A filtration module is provided, the module including at least one filtration packet containing filtration media or one or more membranes, such as a stack of membranes, the at least one filtration packet having one or more fluid ports, the one or more fluid ports being surrounded by a primary seal and a secondary seal spaced from the primary seal. The secondary seals are designed to maintain sterility of the assembly during shipping, handling and/or installation. A removable film may cover one or more fluid ports to maintain sterility prior to use.

公开(公告)号：US12172108B2

公开(公告)日：2024-12-24

申请号：US17262356

申请日：2019-08-12

Applicant: EMD Millipore Corporation

Inventor： Michael James Susienka ,  Jeremy Perreault ,  Joseph Geringer ,  Brian Hillier ,  Joseph Muldoon ,  John Paul Amara

IPC: B01D63/08 ,  B01D27/14 ,  B01D35/30

Abstract: A filtration module is provided, the module including at least one filtration packet containing filtration media or one or more membranes, such as a stack of membranes, the at least one filtration packet having one or more fluid ports, the one or more fluid ports being surrounded by a primary seal and a secondary seal spaced from the primary seal. The secondary seals are designed to maintain sterility of the assembly during shipping, handling and/or installation. A removable film may cover one or more fluid ports to maintain sterility prior to use.

公开(公告)号：US20230302409A1

公开(公告)日：2023-09-28

申请号：US18034243

申请日：2021-11-16

Applicant: EMD Millipore Corporation

Inventor： Heejin Lee ,  Michael James Susienka ,  Johnathan Lawson ,  John Paul Amara ,  Joseph Michael Almasian ,  Sean Foley ,  James Ormond

IPC: B01D61/18 ,  B01D63/08

CPC classification number: B01D61/18 ,  B01D63/082 ,  B01D2313/54 ,  B01D2313/13 ,  B01D2313/105 ,  B01D2313/125 ,  B01D2313/16 ,  B01D2313/06 ,  B01D2313/041

Abstract: An apparatus for treating a biological fluid, comprising a plurality of filtration devices. In some embodiments, each of the plurality of filtration devices comprising at least one inlet and at least one outlet; and a first insert plate and a second insert plate opposite the first insert plate, wherein the plurality of filtration devices is disposed therebetween. In some embodiments, each filtration device has a vent port. A manifold for each of the inlets, outlets, and vent ports is optionally fluidly connected. In another embodiment, hose barb connectors or the like may be protected from damage and/or exposure by being recessed in the device or positioned at a periphery of the device. Embodiments include apparatus and methods to achieve dripless connect/disconnect and to reduce the number of sterile-to-sterile connections.