METHOD AND MEASURING SYSTEM FOR SCANNING A REGION OF INTEREST
    1.
    发明申请
    METHOD AND MEASURING SYSTEM FOR SCANNING A REGION OF INTEREST 审中-公开
    扫描区域的方法和测量系统

    公开(公告)号:WO2010055362A3

    公开(公告)日:2010-07-08

    申请号:PCT/HU2009000095

    申请日:2009-11-17

    Abstract: The invention relates to a method for scanning a region of interest, such as a portion of a neural process, via a laser scanning microscope having focusing means for focusing a laser beam and having electro-mechano-optic deflecting means for deflecting the laser beam, the method comprising: providing a primary scanning trajectory (92a) for the at least one region of interest; providing a plurality of spaced apart (89) auxiliary scanning trajectories (92b) running along the primary scanning trajectory within the region of interest; providing a scanning sequence for scanning the scanning trajectories (192); providing cross-over (94) trajectories between the scanning trajectories of two consecutive scanning trajectories in the scanning sequence. The invention further relates to a measuring system for implementing the method according to the invention.

    Abstract translation: 本发明涉及一种用于通过激光扫描显微镜扫描诸如神经过程的一部分的感兴趣区域的方法,所述激光扫描显微镜具有用于聚焦激光束并具有用于偏转激光束的电机械光学偏转装置的聚焦装置, 所述方法包括:为所述至少一个感兴趣区域提供主扫描轨迹(92a); 提供沿所述感兴趣区域内的主扫描轨迹延伸的多个间隔开的(89)辅助扫描轨迹(92b) 提供用于扫描扫描轨迹(192)的扫描序列; 在扫描序列中的两个连续扫描轨迹的扫描轨迹之间提供交叉(94)轨迹。 本发明还涉及一种用于实现根据本发明的方法的测量系统。

    COMBINED IMAGING SYSTEM AND MRI COMPATIBLE LASER SCANNING MICROSCOPE
    2.
    发明申请
    COMBINED IMAGING SYSTEM AND MRI COMPATIBLE LASER SCANNING MICROSCOPE 审中-公开
    组合成像系统和MRI兼容的激光扫描显微镜

    公开(公告)号:WO2016079547A9

    公开(公告)日:2017-07-13

    申请号:PCT/HU2015000072

    申请日:2015-11-18

    Applicant: FEMTONICS KFT

    CPC classification number: G01R33/4808 G01R33/381 G02B21/002

    Abstract: The subject of the invention relates to a combined imaging system (10') that includes a laser scanning microscope (50, 50'), and a measuring device with a lower resolution than the resolution of the laser scanning microscope (50, 50') and that measures over a larger spatial scale than the spatial scale of the laser scanning microscope (50, 50'). The subject of the invention also relates to an MRI compatible laser scanning microscope which comprises: deflecting means (24') for deflecting a laser beam (13), objective (28'), adjustable objective arm (38), distance adapter (39) and at least one detector (30'). The essence of the MRI compatible laser scanning microscope is that at least the objective (28'), the adjustable objective arm (38), the distance adapter (39) and the at least one detector (30') are made from non-magnetisable materials and the deflecting means (24') is magnetically shielded.

    Abstract translation: 本发明的主题涉及包括激光扫描显微镜(50,50')和分辨率低于激光扫描显微镜(50,50')的分辨率的测量装置的组合成像系统(10'), 并且在比激光扫描显微镜(50,50')的空间尺度更大的空间尺度上进行测量。 本发明的主题还涉及MRI兼容的激光扫描显微镜,其包括:用于偏转激光束(13)的偏转装置(24'),物镜(28'),可调物镜臂(38),距离适配器(39) 和至少一个检测器(30')。 MRI兼容激光扫描显微镜的本质在于至少物镜(28'),可调物镜臂(38),距离适配器(39)和至少一个检测器(30')由不可磁化的 材料和偏转装置(24')被磁屏蔽。

    LASER SCANNING MICROSCOPE FOR SCANNING ALONG A 3D TRAJECTORY
    4.
    发明申请
    LASER SCANNING MICROSCOPE FOR SCANNING ALONG A 3D TRAJECTORY 审中-公开
    用于扫描三维轨迹的激光扫描显微镜

    公开(公告)号:WO2010007452A2

    公开(公告)日:2010-01-21

    申请号:PCT/HU2009000057

    申请日:2009-07-14

    CPC classification number: G02B21/0048 G02B21/006 G02B21/0084

    Abstract: The invention relates to a laser scanning microscope (10) having: focusing means (15) having a focal plane (29) and comprising at least one optical element for focusing a laser beam (13); drive means (18) for displacing the at least one optical element of the focusing means (15) for changing the position of the focal plane (29), and deflecting means (14) for deflecting the laser beam (13). The microscope comprises a control system (32) configured to carry out the steps of: providing a periodical drive signal for the drive means (18); obtaining time dependant displacement data of the at least one optical element of the focusing means (15) in response to the periodical drive signal of the drive means (18); providing a response function (z(t)) using the time dependant displacement data, calculating a drive signal for the deflecting means (14) using the response function (z(t)) to move the focal volume (30) of the laser beam (13) along a given 3D trajectory (48) within a sample to be examined. The invention further relates to a method for carrying out such a scanning operation along a 3D trajectory (48). ?

    Abstract translation: 本发明涉及一种激光扫描显微镜(10),其具有:聚焦装置(15),其具有焦平面(29)并且包括用于聚焦激光束(13)的至少一个光学元件; 用于移动聚焦装置(15)的至少一个光学元件以改变焦平面(29)的位置的驱动装置(18)和用于偏转激光束(13)的偏转装置(14)。 该显微镜包括控制系统(32),该控制系统(32)被配置为执行以下步骤:为驱动装置(18)提供周期性驱动信号; 响应驱动装置(18)的周期性驱动信号获得聚焦装置(15)的至少一个光学元件的时间相关位移数据; 使用所述时间相关位移数据提供响应函数(z(t)),使用所述响应函数(z(t))计算用于所述偏转装置(14)的驱动信号以移动所述激光束的所述焦点容积(30) (13)沿着要检查的样本内的给定3D轨迹(48)。 本发明还涉及用于沿着3D轨迹(48)执行这种扫描操作的方法。 ?

    COMPENSATOR SYSTEM AND METHOD FOR COMPENSATING ANGULAR DISPERSION

    公开(公告)号:CA2861716C

    公开(公告)日:2019-05-14

    申请号:CA2861716

    申请日:2012-01-05

    Applicant: FEMTONICS KFT

    Abstract: The invention relates to a compensator system adapted to compensate for the angular dispersion of electromagnetic beams deflected by at least one acousto-optic deflector. The compensator system comprises: - a first lens group for spatially separating the deflected beams of different deflection angle and angular dispersion, - a compensator element having a first surface and a second surface that together work as prisms with tilt angles .beta. and prism opening angles ap that vary with the distance from the optical axis so as to compensate for the angular dispersion of the spatially separated deflected beams, - a second lens group arranged so as to substantially parallelise the different wavelength components of each deflected beam while maintaining the angular variation of the beams deflected at different acoustic frequencies. The invention further relates to a corresponding method for compensating for the angular dispersion of electromagnetic beams deflected by an acousto-optic deflector.

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