公开(公告)号：CA2526368A1

公开(公告)日：2004-12-02

申请号：CA2526368

申请日：2004-05-20

Applicant: FLUIDIGM CORP

Inventor： TAYLOR COLIN JON ,  LEE MICHAEL ,  SUN GANG ,  QUAN EMERSON CHUENG ,  CEASAR CHRISTOPHER G ,  HARRIS GREG

IPC: B01L3/00 ,  B29D11/00 ,  B44C1/22 ,  C02F1/40 ,  F15C1/04 ,  F15C1/06 ,  G01N21/00 ,  G01N33/558 ,  G01N35/02

Abstract: A biological substrate, e.g., microfluidic chip. The substrate includes a rigid substrate material, which has a surface region capable of acting as a handle substrate. The substrate also has a deformable fluid layer coupled to the surface region. One or more well regions are formed in a first portion of the deformable fluid layer and are capable of holding a fluid therein. The one or more channel regions are formed in a second portion of the deformable fluid layer and are coupled to one or more of the well regions. An active region is formed in the deformable fluid layer. At least three fiducial markings are formed within the non-active region and disposed in a spatial manner associated with at least one of the well regions. A control layer is coupled to the fluid layer.

公开(公告)号：AU2004240944A1

公开(公告)日：2004-12-02

申请号：AU2004240944

申请日：2004-05-20

Applicant: FLUIDIGM CORP

Inventor： TAYLOR COLIN JON ,  CEASAR CHRISTOPHER ,  SUN GANG ,  QUAN EMERSON CHUENG ,  HARRIS GREG ,  LEE MICHAEL

IPC: B29D11/00 ,  B44C1/22 ,  C02F1/40 ,  F15C1/04 ,  F15C1/06 ,  G01N21/00 ,  G01N33/558 ,  G01N35/02 ,  B01L3/00

Abstract: A biological substrate, e.g., microfluidic chip. The substrate includes a rigid substrate material, which has a surface region capable of acting as a handle substrate. The substrate also has a deformable fluid layer coupled to the surface region. One or more well regions are formed in a first portion of the deformable fluid layer and are capable of holding a fluid therein. The one or more channel regions are formed in a second portion of the deformable fluid layer and are coupled to one or more of the well regions. An active region is formed in the deformable fluid layer. At least three fiducial markings are formed within the non-active region and disposed in a spatial manner associated with at least one of the well regions. A control layer is coupled to the fluid layer.