公开(公告)号：EP3201599A1

公开(公告)日：2017-08-09

申请号：EP15771133.4

申请日：2015-09-30

Applicant: FOSS Analytical A/S

Inventor： RINDORF, Lars Henning ,  GLÜCKSTAD, Jesper ,  AABO, Thomas

IPC: G01N15/14 ,  B01L3/00 ,  G01N15/10 ,  G01N15/00

CPC classification number: G01N15/1404 ,  B01L3/502746 ,  B01L3/502761 ,  B01L3/502776 ,  B01L2200/0636 ,  B01L2200/0652 ,  B01L2300/0654 ,  B01L2300/0864 ,  B01L2400/0454 ,  B01L2400/082 ,  G01N15/147 ,  G01N15/1484 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/1413 ,  G01N2015/1415 ,  G01N2015/149

Abstract: In a method for hydrodynamic focusing of a laminar and planar sample fluid flow, a system is provided for analysis and/or sorting of microscopic objects in the sample fluid comprising an optical objective for optical inspection of the microscopic objects. Microscopic objects are conveyed in the laminar flow of the sample fluid, and two laminar and planar flow of sheath fluids are provided. The flow of the sample fluid is hydrodynamically focussed at an optical inspection zone of the system by the sheath fluids. Focussing of the flow of the sample fluid is controlled such that all of the microscopic objects in the sample fluid are caused to be conveyed in a common flow direction in one single plane at the inspection zone of the system, and the microscopic objects in the fluid are optically inspected through the optical objective.

Abstract translation: 在用于层流和平面样品流体流动的流体动力聚焦的方法中，提供了用于分析和/或分选样品流体中的微观物体的系统，其包括用于光学检查微观物体的光学物镜。 微观物体在样品流体的层流中传送，并提供两层层流和平面流体的鞘液。 样品流体的流动通过鞘液在流体动力学聚焦在系统的光学检查区。 控制样本流体的流动，使得样本流体中的所有微观物体在系统的检查区域中在一个单一平面内以共同流动方向被传送，并且流体中的微观物体 通过光学物镜进行光学检查。

公开(公告)号：WO2017141075A1

公开(公告)日：2017-08-24

申请号：PCT/IB2016/050897

申请日：2016-02-19

Applicant: FOSS ANALYTICAL A/S

Inventor： RINDORF, Lars Henning

IPC: B01D1/00 ,  B01D1/18 ,  B01D5/00 ,  A23C1/04 ,  A23C1/12 ,  A23C9/18 ,  A23C21/00 ,  A23L5/30 ,  A23L2/08 ,  A23L2/10

CPC classification number: B01D1/18 ,  A23C1/04 ,  A23C1/12 ,  A23C9/18 ,  A23C21/00 ,  A23L2/08 ,  A23L2/10 ,  A23L2/102 ,  A23L5/51 ,  B01D1/00 ,  B01D1/0082 ,  B01D5/00 ,  B01D5/006

Abstract: A system for manufacturing a concentrate from a liquid source material (30) containing constituents in solution or suspension, the system comprising an evaporator (2) configured to output a liquid concentrate (10) having a concentration of at least one of the constituents higher than a desired concentration; a detector (24) configured to measure on the liquid concentrate in a flow conduit (8) and to generate a signal indicative of the concentration of the at least one of the constituents; and a metering device (16) in fluid communication with a source of metering liquid (22) and with the liquid concentrate (10). The metering device (16) is configured to meter a quantity of the metering liquid into the liquid concentrate (10) in dependence of the signal to achieve a liquid concentrate having the desired concentration.

Abstract translation: 一种用于由含有溶液或悬浮液中的成分的液体源材料（30）制造浓缩物的系统，所述系统包括蒸发器（2），所述蒸发器（2）配置成输出浓度为 至少一种成分高于所需浓度; 检测器（24），所述检测器（24）被配置为测量所述流体导管（8）中的所述液体浓缩物并且生成指示所述至少一种成分的浓度的信号; 和与计量液体源（22）和液体浓缩物（10）流体连通的计量装置（16）。 计量装置（16）被配置成根据信号计量进入浓缩液（10）中的一定量的计量液体以获得具有所需浓度的液体浓缩物。

公开(公告)号：WO2016050837A1

公开(公告)日：2016-04-07

申请号：PCT/EP2015/072545

申请日：2015-09-30

Applicant: FOSS ANALYTICAL A/S

Inventor： RINDORF, Lars Henning ,  GLÜCKSTAD, Jesper ,  AABO, Thomas

IPC: G01N15/14 ,  B01L3/00 ,  G01N15/10 ,  G01N15/00

CPC classification number: G01N15/1404 ,  B01L3/502746 ,  B01L3/502761 ,  B01L3/502776 ,  B01L2200/0636 ,  B01L2200/0652 ,  B01L2300/0654 ,  B01L2300/0864 ,  B01L2400/0454 ,  B01L2400/082 ,  G01N15/147 ,  G01N15/1484 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/1413 ,  G01N2015/1415 ,  G01N2015/149

Abstract: In a method for hydrodynamic focusing of a laminar and planar sample fluid flow, a system is provided for analysis and/or sorting of microscopic objects in the sample fluid comprising an optical objective for optical inspection of the microscopic objects. Microscopic objects are conveyed in the laminar flow of the sample fluid, and two laminar and planar flow of sheath fluids are provided. The flow of the sample fluid is hydrodynamically focussed at an optical inspection zone of the system by the sheath fluids. Focussing of the flow of the sample fluid is controlled such that all of the microscopic objects in the sample fluid are caused to be conveyed in a common flow direction in one single plane at the inspection zone of the system, and the microscopic objects in the fluid are optically inspected through the optical objective.

Abstract translation: 在层流和平面样品流体流动的流体动力学聚焦的方法中，提供用于分析和/或分类样品流体中的微观物体的系统，其包括用于光学检查微观物体的光学物镜。 微观物体在样品流体的层流中传送，并且提供两个层流和平面的护套流体流。 样品流体的流动通过鞘液在流体动力学上集中在系统的光学检查区域。 控制样品流动的聚焦，使得样品流体中的所有微观物体在系统的检查区域的一个单一平面中沿共同的流动方向被输送，并且流体中的微观物体 通过光学物镜进行光学检查。