公开(公告)号：US20220280691A1

公开(公告)日：2022-09-08

申请号：US17631853

申请日：2020-07-10

Applicant: FREIE UNIVERSITÄT BERLIN

Inventor： Marie WEINHART ,  Laura ELOMAA

IPC: A61L27/26 ,  A61L27/22 ,  A61L27/36 ,  A61L27/18 ,  A61L27/16 ,  B29C64/129 ,  B29C64/40

Abstract: A photocurable composition for 3D printing includes a) at least one photocurable prepolymer chosen from the group consisting of functionalized gelatin bearing a first functional group and functionalized decellularized extracellular matrix bearing a second functional group; b) at least one solvent, the solvent being formamide; and c) at least one photoinitiator.

公开(公告)号：US20190169463A1

公开(公告)日：2019-06-06

申请号：US16314630

申请日：2017-06-30

Applicant: FREIE UNIVERSITÄT BERLIN

Inventor： Rainer HAAG ,  Marie WEINHART ,  Qiang WEI ,  Leixiao YU

IPC: C09D171/02 ,  C08G65/22 ,  C08G65/334 ,  C09D5/00 ,  C12M1/00

Abstract: The disclosure relates to an amphiphilic block copolymer comprising a first block consisting of a polymeric hydrophilic domain, wherein the polymeric hydrophilic domain consists of a polyglycerol; an optional second block consisting of a hydrophobic domain and a first linker domain, wherein the second block is covalently bound to the first block via the first linker domain, an optional third block consisting of a catechol domain and a second linker domain, wherein the third block is covalently bound to the first block via the second linker domain; and a fourth block consisting of a crosslinking domain and a third linker domain, wherein the fourth block is covalently bound to the first block via the third linker domain, wherein the crosslinking domain comprises a reactive residue enabling a crosslinking between individual molecules of the amphiphilic block copolymer.

公开(公告)号：US20160222224A1

公开(公告)日：2016-08-04

申请号：US15021250

申请日：2014-09-08

Applicant: FREIE UNIVERSITÄT BERLIN

Inventor： Rainer HAAG ,  Marie WEINHART ,  Qiang WEI ,  Tobias BECHERER ,  Ingo GRUNWALD

IPC: C09D5/16 ,  A61F2/00 ,  A61L27/34 ,  C09D171/00 ,  C12M1/00

CPC classification number: C09D5/1693 ,  A61F2/0077 ,  A61F2002/009 ,  A61L27/34 ,  A61L2420/08 ,  C08G83/006 ,  C08J7/042 ,  C08J2300/202 ,  C08L101/005 ,  C09D171/00 ,  C09D201/005 ,  C09D201/06 ,  C12M23/20 ,  C08L101/02

Abstract: An article, comprising a substrate and a polymer film attached to the substrate is provided, the polymer film comprising a first layer of a first polymer functionalized by a first functionalization compound covalently bound to said first polymer and bearing at least one catecholic group being present on a surface of the first layer. The polymer film is a layered film, a top layer of which is formed by the first layer, the layered film comprising at least one further layer of at least one further polymer functionalized by a further functionalization compound covalently bound to said further polymer and bearing at least one catecholic group being present on a surface of the at least one further layer, wherein an average ratio of catecholic groups per polymer molecule is equal to or less than 1 in case of the first polymer and greater than 1 in case of the further polymer.

Abstract translation: 提供了一种包括基材和连接到基底上的聚合物膜的制品，该聚合物薄膜包括第一聚合物层，该第一层被第一官能化化合物官能化，该第一官能化化合物共价结合到所述第一聚合物上并带有至少一个儿茶酚基， 第一层的表面。 所述聚合物膜是层压膜，其顶层由第一层形成，所述层状膜包含至少一个另外的另外的层，所述至少一个另外的聚合物通过与所述另外的聚合物共价结合的另外的官能化化合物官能化并承载在 至少一个儿茶酚基团存在于至少一个另外的层的表面上，其中在聚合物分子的情况下，每个聚合物分子的儿茶酚基团的平均比例等于或小于1，在另外的聚合物的情况下大于1 。