公开(公告)号：EP2821467A1

公开(公告)日：2015-01-07

申请号：EP12869212.6

申请日：2012-02-24

Applicant: Fain-Biomedical Inc.

Inventor： IKEDA, Seiichi

IPC: C10M173/02 ,  C10N10/02 ,  C10N10/04 ,  C10N10/06 ,  C10N10/16 ,  C10N30/06 ,  C10N40/00

CPC classification number: C10M141/08 ,  A61L29/14 ,  A61L2400/10 ,  A61M2025/0046 ,  A61M2025/0062 ,  C10M173/02 ,  C10M2201/08 ,  C10M2201/081 ,  C10M2201/084 ,  C10M2207/122 ,  C10M2209/108 ,  C10M2215/02 ,  C10M2215/04 ,  C10M2215/082 ,  C10M2219/042 ,  C10M2219/044 ,  C10N2230/06 ,  C10N2240/66

Abstract: The present invention makes the insertion perception during actual surgery to be equivalent to the insertion perception of a catheter into a blood vessel model when water is used as the circulating fluid. A lubricant regulating fluid primarily composed of water is mixed with an aqueous metal salt and a surfactant as a lubricant regulating agent of the lubricant regulating fluid. A cationic surfactant, an anionic surfactant, a nonionic surfactant, or a dipolar ionic surfactant may be used as the surfactant. Also, the metal salt may be an alkaline metal salt, an alkaline earth metal salt, an aluminum salt, a ferric salt, or the like. In an example, the lubricant regulating fluid obtained by mixing an aqueous metal salt with water is prepared, and the lubrication and non-adherent properties of a catheter into a simulated blood vessel model are improved.

Abstract translation: 本发明使得在实际手术期间的插入感觉等同于当将水用作循环流体时将导管插入血管模型中的插入感知。 主要由水组成的润滑剂调节流体与作为润滑剂调节流体的润滑剂调节剂的金属盐水溶液和表面活性剂混合。 阳离子表面活性剂，阴离子表面活性剂，非离子表面活性剂或偶极离子表面活性剂可以用作表面活性剂。 此外，金属盐可以是碱金属盐，碱土金属盐，铝盐，铁盐等。 在一个实例中，制备通过混合水性金属盐与水而获得的润滑剂调节流体，并且改善了导管在模拟血管模型中的润滑性和非粘附性。

公开(公告)号：EP2821467B1

公开(公告)日：2018-02-14

申请号：EP12869212.6

申请日：2012-02-24

Applicant: Fain-Biomedical Inc.

Inventor： IKEDA, Seiichi

IPC: C10M173/02 ,  C10N10/02 ,  C10N10/04 ,  C10N10/06 ,  C10N10/16 ,  C10N30/06 ,  C10N40/00 ,  B29C33/60

CPC classification number: C10M141/08 ,  A61L29/14 ,  A61L2400/10 ,  A61M2025/0046 ,  A61M2025/0062 ,  C10M173/02 ,  C10M2201/08 ,  C10M2201/081 ,  C10M2201/084 ,  C10M2207/122 ,  C10M2209/108 ,  C10M2215/02 ,  C10M2215/04 ,  C10M2215/082 ,  C10M2219/042 ,  C10M2219/044 ,  C10N2230/06 ,  C10N2240/66

Abstract: The present invention makes the insertion perception during actual surgery to be equivalent to the insertion perception of a catheter into a blood vessel model when water is used as the circulating fluid. A lubricant regulating fluid primarily composed of water is mixed with an aqueous metal salt and a surfactant as a lubricant regulating agent of the lubricant regulating fluid. A cationic surfactant, an anionic surfactant, a nonionic surfactant, or a dipolar ionic surfactant may be used as the surfactant. Also, the metal salt may be an alkaline metal salt, an alkaline earth metal salt, an aluminum salt, a ferric salt, or the like. In an example, the lubricant regulating fluid obtained by mixing an aqueous metal salt with water is prepared, and the lubrication and non-adherent properties of a catheter into a simulated blood vessel model are improved.