公开(公告)号：US11674928B2

公开(公告)日：2023-06-13

申请号：US16010617

申请日：2018-06-18

Applicant: Foundation for Research and Technology Hellas

Inventor： Georgios Papadakis ,  Electra Gizeli

IPC: C12Q1/6825 ,  C12Q1/6844 ,  C12Q1/6806 ,  C12Q1/6853 ,  G01N29/032 ,  G01N33/02 ,  G01N33/487

CPC classification number: G01N29/032 ,  C12Q1/6806 ,  C12Q1/6825 ,  C12Q1/6844 ,  C12Q1/6853 ,  G01N33/02 ,  G01N33/487 ,  G01N2291/022 ,  G01N2291/02809 ,  C12Q1/6806 ,  C12Q2565/634 ,  C12Q1/6844 ,  C12Q2565/634 ,  C12Q1/6825 ,  C12Q2565/634

Abstract: An acoustic sensor detects binding of a nucleic acid analyte in an impure liquid sample by measurement of the energy of the acoustic wave resulting from the binding of the nucleic acid target to the sensor surface. The analysis may be preceded by carrying out a nucleic acid amplification procedure in situ on a crude or impure biological sample and the analysis is tolerant of the presence of reagents or by-products of the amplification procedure, and also materials present from the initial biological sample.

公开(公告)号：US20190011401A1

公开(公告)日：2019-01-10

申请号：US16010617

申请日：2018-06-18

Applicant: Foundation for Research and Technology Hellas

Inventor： Georgios Papadakis ,  Electra Gizelli

IPC: G01N29/032 ,  C12Q1/6853 ,  G01N33/487 ,  G01N33/02

Abstract: An acoustic sensor detects binding of a nucleic acid analyte in an impure liquid sample by measurement of the energy of the acoustic wave resulting from the binding of the nucleic acid target to the sensor surface. The analysis may be preceded by carrying out a nucleic acid amplification procedure in situ on a crude or impure biological sample and the analysis is tolerant of the presence of reagents or by-products of the amplification procedure, and also materials present from the initial biological sample.