公开(公告)号：WO2007021508A3

公开(公告)日：2007-06-28

申请号：PCT/US2006029561

申请日：2006-07-28

Applicant: GEN ELECTRIC ,  BUTTS MATTHEW DAVID ,  GENOVESE SARAH ELIZABETH ,  GLASER PAUL BURCHELL ,  WILLIAMS DARRYL STEPHEN

Inventor： BUTTS MATTHEW DAVID ,  GENOVESE SARAH ELIZABETH ,  GLASER PAUL BURCHELL ,  WILLIAMS DARRYL STEPHEN

IPC: C01B33/18

CPC classification number: C01B33/18

Abstract: Methods for making hollow silica particle are disclosed, said particles made from a composition comprising a silicon-containing compound selected from the group consisting of tetraalkoxysilanes, trialkyloxysilanes and derivatives thereof, dialkoxysilanes and derivatives thereof, alkoxysilanes and derivatives thereof, silicone oligomers, oligomeric silsesquioxanes and silicone polymers distributed over a polymer template core that is eliminated from the particle. The particles of the present invention have a substantially uniform particle size and exhibit low permeability to liquids.

Abstract translation: 公开了制备中空二氧化硅颗粒的方法，所述颗粒由包含选自四烷氧基硅烷，三烷氧基硅烷及其衍生物，二烷氧基硅烷及其衍生物，烷氧基硅烷及其衍生物，硅氧烷低聚物，低聚倍半硅氧烷， 分散在聚合物模板芯上的硅氧烷聚合物被从颗粒中除去。 本发明的颗粒具有基本均匀的颗粒尺寸并且对液体表现出低渗透性。

公开(公告)号：WO2010076237A3

公开(公告)日：2011-02-03

申请号：PCT/EP2009067468

申请日：2009-12-18

Applicant: GEN ELECTRIC ,  GE HEALTHCARE AS ,  COLBORN ROBERT EDGAR ,  BONITATIBUS JR PETER JOHN ,  TORRES ANDREW SOLIZ ,  MARINO MICHAEL ERNEST ,  BUTTS MATTHEW DAVID ,  KULKARNI AMIT ,  BALES BRIAN C ,  HAY BRUCE ALLAN

Inventor： COLBORN ROBERT EDGAR ,  BONITATIBUS JR PETER JOHN ,  TORRES ANDREW SOLIZ ,  MARINO MICHAEL ERNEST ,  BUTTS MATTHEW DAVID ,  KULKARNI AMIT ,  BALES BRIAN C ,  HAY BRUCE ALLAN

IPC: A61K49/04 ,  A61K49/18

CPC classification number: A61K49/0428 ,  A61K49/1848 ,  B82Y5/00

Abstract: Nanoparticles (10) functionalized with at least one zwitterionic moiety, and compositions comprising said nanoparticles are provided. The nanoparticles (10) have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle (10) comprises a core (20), having a core surface (30) essentially free of silica, and a shell (40) attached to the core surface (30). The shell (40) comprises at least one silane- functionalized zwitterionic moiety. Further, methods of making said nanoparticles and methods of their use as diagnostic agents are provided.

Abstract translation: 提供用至少一个两性离子部分官能化的纳米颗粒（10）和包含所述纳米颗粒的组合物。 与其他纳米颗粒相比，纳米颗粒（10）具有导致颗粒在体内的最小保留的特征。 纳米颗粒（10）包括具有基本上不含二氧化硅的芯表面（30）和连接到芯表面（30）的壳体（40）的芯体（20）。 壳（40）包含至少一个硅烷官能化的两性离子部分。 此外，提供制备所述纳米颗粒的方法及其用作诊断剂的方法。

公开(公告)号：WO2010125088A2

公开(公告)日：2010-11-04

申请号：PCT/EP2010055685

申请日：2010-04-28

Applicant: GEN ELECTRIC ,  GE HEALTHCARE AS ,  COLBORN ROBERT EDGAR ,  BONITATIBUS JR PETER JOHN ,  TORRES ANDREW SOLIZ ,  MARINO MICHAEL ERNEST ,  BUTTS MATTHEW DAVID ,  KULKARNI AMIT ,  BALES BRIAN C ,  HAY BRUCE ALLAN

Inventor： COLBORN ROBERT EDGAR ,  BONITATIBUS JR PETER JOHN ,  TORRES ANDREW SOLIZ ,  MARINO MICHAEL ERNEST ,  BUTTS MATTHEW DAVID ,  KULKARNI AMIT ,  BALES BRIAN C ,  HAY BRUCE ALLAN

IPC: A61K49/04

CPC classification number: A61K49/0428 ,  A61K49/1848 ,  B82Y5/00

Abstract: Compositions of nanoparticles functionalized with at least one net positively charged group and at least one net negatively charged group, methods for making a plurality of nanoparticles, and methods of their use as diagnostic agents are provided. The nanoparticles have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle comprises a coreand a shell. The shell comprises a plurality of silane moieties; at least one silane moiety of the plurality is functionalized with a net positively charged group and at least one silane moiety of the plurality is functionalized with a net negatively charged group.

Abstract translation: 提供了用至少一个净正电荷基团和至少一个净负电荷基团官能化的纳米颗粒的组合物，制备多个纳米颗粒的方法及其用作诊断剂的方法。 与其他纳米颗粒相比，纳米颗粒具有导致颗粒在体内的最小保留的特征。 纳米颗粒包括芯和壳。 壳包含多个硅烷部分; 多个的至少一个硅烷部分用净正电荷基团官能化，并且多个的至少一个硅烷部分用净带负电基团官能化。

公开(公告)号：WO0040210A2

公开(公告)日：2000-07-13

申请号：PCT/US0000444

申请日：2000-01-07

Applicant: PROCTER & GAMBLE ,  GEN ELECTRIC

Inventor： GLENN ROBERT WAYNE JR ,  KATRITZKY ALAN ROY ,  BLOCK ERIC ,  SHAIR MATTHEW DAVID ,  BUTTS MATTHEW DAVID

IPC: C07D233/84 ,  A61K8/00 ,  A61K8/30 ,  A61K8/46 ,  A61K8/49 ,  A61K8/69 ,  A61K8/72 ,  A61K8/89 ,  A61K8/891 ,  A61K8/893 ,  A61K8/898 ,  A61K8/899 ,  A61K31/145 ,  A61K31/18 ,  A61K31/21 ,  A61K31/265 ,  A61K31/4164 ,  A61K31/428 ,  A61K31/4425 ,  A61K31/505 ,  A61K31/506 ,  A61K31/80 ,  A61P17/00 ,  A61Q1/00 ,  A61Q1/10 ,  A61Q3/00 ,  A61Q3/02 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q17/02 ,  A61Q19/00 ,  C07C321/22 ,  C07C323/29 ,  C07C323/52 ,  C07C323/65 ,  C07C327/22 ,  C07C327/30 ,  C07C327/42 ,  C07C329/16 ,  C07D213/70 ,  C07D239/38 ,  C07D277/74 ,  C07D403/12 ,  C07F7/10 ,  C07F9/00 ,  A61K7/00

CPC classification number: A61K8/898 ,  A61K8/46 ,  A61K8/49 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/4946 ,  A61K8/4953 ,  A61K8/496 ,  A61K8/69 ,  A61K8/899 ,  A61Q3/00 ,  A61Q5/00 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00

Abstract: This invention relates to a topical composition for treating amino acid based substrates comprising a protected thiol compound having the formula R—(S—Pr)m where R is a functional group, S is sulfur, and Pr is a heterocyclic protecting group, and m is an integer between 1 and 100. The invention further relates to systems which comprise this protected thiol compound and an activating mechanism. The protected thiol compounds of the present invention may be used in hair care compositions, textile care compositions, cosmetic compositions, oral care compositions, skin care, nail care, laundry care, acne care and animal care compositions. A preferred embodiment of the present invention provides a silicone composition and method for making. The composition comprises a polysiloxane or silicone resin, at least one linker, and at least one molecular hook.

Abstract translation: 本发明涉及一种用于处理氨基酸基底物的局部组合物，其包含具有式R-（S-Pr）m的保护的硫醇化合物，其中R是官能团，S是硫，Pr是杂环保护基，m 是1至100之间的整数。本发明还涉及包含该受保护的硫醇化合物和活化机理的体系。 本发明的受保护的硫醇化合物可以用于护发组合物，纺织品护理组合物，化妆品组合物，口腔护理组合物，护肤品，指甲护理，洗衣护理，痤疮护理和动物护理组合物中。 本发明的优选实施方案提供一种硅氧烷组合物和制备方法。 组合物包含聚硅氧烷或有机硅树脂，至少一个接头和至少一个分子钩。

公开(公告)号：JP2001064293A

公开(公告)日：2001-03-13

申请号：JP2000133929

申请日：2000-05-02

Applicant: GEN ELECTRIC

Inventor： BUTTS MATTHEW DAVID

IPC: C07F19/00 ,  C07F15/00 ,  C07F17/02 ,  C08K5/56 ,  C08L83/04 ,  C08L83/07 ,  C09D5/00 ,  C09D183/04 ,  C09D183/07

Abstract: PROBLEM TO BE SOLVED: To obtain a novel compound bearing a tri-substituted silyl-aliphatic group that bonds to platinum with a carbon-platinum bond, which is useful for curing an irradiation-curable silicone composition to which the addition reaction between a silicon-bonding hydride and an aliphatic unsaturated group- containing substance participates. SOLUTION: This novel compound is an optically active cyclo-pentadienyl platinum (IV) compound bearing a tri-substituted silylaliphatic group that is boned to platinum via a carbon-platinum bond, typically [1-methyl-3-(9'- phenanthrylmethyl)cyclopentadienyl] dimethyltrimethylsilylmethylplatinum. This exemplified compound is prepared by allowing a compound of formula I: Pt (CH3)2CH2Si(CH3)3 to react with lithium 1-methyl-3-(9'-phenanthril)- cyclopentadienide.

公开(公告)号：JPH10330384A

公开(公告)日：1998-12-15

申请号：JP6917698

申请日：1998-03-19

Applicant: GEN ELECTRIC

Inventor： WHITE MICHAEL LEE ,  BAGHEL SUNITA SINGH ,  TOLENTINO LUISITO ALVAREZ ,  BARR MARK KROMER ,  DE MOULPIED DAVID CHENEY ,  GATELY WILLIAM LEE ,  GOEDMAKERS JAN-WILLEM ,  HALLEN JEFFREY DAVID ,  KENNEDY EDWARD FRANCIS ,  KIM BANG MO ,  SHADE RAY WOLTON ,  BUTTS MATTHEW DAVID

IPC: C07F7/12 ,  C07F7/16 ,  C07F7/20

Abstract: PROBLEM TO BE SOLVED: To produce a compound having high copper content and reduce heavy metal concentration in waste water and treat the subject by-product by hydrolyzing the by-product under specific conditions in an aqueous medium containing methylchlorosilanes which are production products and a surfactant. SOLUTION: A by-product is hydrolyzed at least at pH about 7 and a temperature higher than about 0 deg.C in an aqueous medium containing a product and as necessarily a surfactant such as an alkylpolyether alcohol, a polyethylenealkyloxy alcohol or polyoxyethylene (4) lauryl ether in a method for producing at least two separable phases by treating a by-product produced during production of methylchlorosilanes. Thereby, two separable phases composed of a first phase containing an inert solid having high copper content and a second phase not containing a heavy metal and comprising an aqueous solution suitable for disposing into industrial waste fluid by further carrying out treatment or without carrying out further treatment are produced to treat the by-product.

公开(公告)号：JP2001089491A

公开(公告)日：2001-04-03

申请号：JP2000133930

申请日：2000-05-02

Applicant: GEN ELECTRIC

Inventor： BUTTS MATTHEW DAVID

IPC: C07F15/00 ,  C07F17/02 ,  C08F2/50 ,  C08F4/80 ,  C08L83/04 ,  C08L83/07 ,  C09D5/00 ,  C09D183/04 ,  C09D183/07

Abstract: PROBLEM TO BE SOLVED: To provide a photoactive platinum (IV) compound and a method imparting an improved curing rate and storing stability to an irradiation curable silicone mixture as a curing catalyst for irradiation curable silicone composition. SOLUTION: This photoactive platinum (IV) compound is a cyclopentadienyl platinum (IV) compound having 7-20C aromatic substituent on the cyclopentadienyl ring expressed by the following formula. [(R1)a(R2)bCp]Pt(R3)3 (R1 is a 7-20C aromatic group, R2 and R3 are independently a 1-22C aliphatic group, Cp is a cyclopentadienyl group, a is an integer of 1-3, b is a integer of 0-3, a+b=1-4).

公开(公告)号：JPH1171382A

公开(公告)日：1999-03-16

申请号：JP14522798

申请日：1998-05-27

Applicant: GEN ELECTRIC

Inventor： WHITE MICHAEL LEE ,  BUTTS MATTHEW DAVID ,  DE MOULPIED DAVID CHENEY

IPC: A62D3/34 ,  A62D3/35 ,  A62D3/36 ,  A62D3/37 ,  A62D3/38 ,  A62D101/22 ,  C07B35/06 ,  C07F7/12 ,  C07F7/16 ,  A62D3/00

Abstract: PROBLEM TO BE SOLVED: To provide a process that can reduce the chlorine content of the by-products occurring in the production of methylchlorosilanes. SOLUTION: This process comprises the following steps: (a) the by-products are combined with optionally surfactant-containing aqueous medium at least at a pH of about 7 and a temperature higher than about 0 deg.C to hydrolyze the by-product into the first phase essentially containing solid and the second phase containing the aqueous phase; (b) the first phase is separated from the second phase; (c) the solid from the first phase is oxidized at least at about 300 deg.C for

公开(公告)号：JP2002146192A

公开(公告)日：2002-05-22

申请号：JP2001212952

申请日：2001-07-13

Applicant: GEN ELECTRIC

Inventor： BUTTS MATTHEW DAVID ,  NYE SUSAN ADAMS ,  BYRNE CHRISTOPHER MICHAEL

IPC: A61K8/72 ,  A61K8/00 ,  A61K8/89 ,  A61K8/893 ,  A61K8/894 ,  A61K8/898 ,  A61K8/899 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q11/00 ,  C08G77/38 ,  C08G77/388 ,  C08G77/392 ,  C08G77/42 ,  C08K5/34 ,  C08L71/02 ,  C08L79/02 ,  C08L83/04 ,  A61K7/00 ,  A61K7/06 ,  A61K7/16

Abstract: PROBLEM TO BE SOLVED: To provide a silicone resin composition usable for the treatment of damaged hair to exhibit a conditioning effect and a durable effect and provide a method for producing the composition. SOLUTION: The silicone composition is composed of one or more kinds of polysiloxane or silicone resin, one or more molecular hooks selected from heterocyclic pyridinium compound, heterocyclic triazinium compound, heterocyclic pyrimidium compound and heterocyclic pyrazine compound and one or more linkers having polyether bond and polyamino bond. The composition is effectively usable as a hair treating preparation, cosmetic or mouth wash, a preparation for animals for the above purpose and a preparation for the treatment of woven fabric.

公开(公告)号：JP2002155205A

公开(公告)日：2002-05-28

申请号：JP2001212951

申请日：2001-07-13

Applicant: GEN ELECTRIC

Inventor： BUTTS MATTHEW DAVID ,  NYE SUSAN ADAMS ,  BYRNE CHRISTOPHER MICHAEL

IPC: A61K8/00 ,  A61K8/89 ,  A61K8/891 ,  A61K8/893 ,  A61K8/895 ,  A61K8/898 ,  A61Q5/00 ,  A61Q5/12 ,  C08G77/22 ,  C08G77/385 ,  C08G77/388 ,  C08G77/42 ,  C08G77/46 ,  C08L83/04 ,  C08L83/08 ,  C08L83/10 ,  A61K7/06

Abstract: PROBLEM TO BE SOLVED: To obtain a silicone composition which can be used to treat damaged hair and provide durable benefits, namely a silicon product which can both covalently bond to hair as well as impart hair care benefits appreciated by consumers. SOLUTION: This silicone composition comprises at least one polysiloxane or silicone resin, at least one linker, and at least one molecular hook. This method for producing the silicone composition is provided. The molecular hook comprises a heterocyclic trimethylpyrimidinium compound. This care product and this cosmetic comprise the composition.