公开(公告)号：ZA907573B

公开(公告)日：1991-09-25

申请号：ZA907573

申请日：1990-09-21

Applicant: GLAXO INC

Inventor： WHEELER THOMAS N ,  THOMAS N WHEELER ,  SHAFFER JOEL E ,  JOEL E SHAFFER ,  KENAKIN TERRENCE ,  TERRENCE KENAKIN

IPC: A61K20060101 ,  C07D20060101 ,  C07D ,  A61K

公开(公告)号：AU644605B2

公开(公告)日：1993-12-16

申请号：AU6310090

申请日：1990-09-21

Applicant: GLAXO INC

Inventor： WHEELER THOMAS N ,  SHAFFER JOEL E ,  KENAKIN TERRENCE

IPC: A61K31/44 ,  A61K31/4418 ,  A61P9/00 ,  C07D213/85 ,  A61K31/535 ,  C07D413/12

公开(公告)号：CA2025967A1

公开(公告)日：1991-03-23

申请号：CA2025967

申请日：1990-09-21

Applicant: GLAXO INC

Inventor： WHEELER THOMAS N ,  SHAFFER JOEL E ,  KENAKIN TERRENCE

IPC: A61K31/44 ,  A61K31/4418 ,  A61P9/00 ,  C07D213/85 ,  A61K31/535 ,  C07D413/12

Abstract: Pyridones of formula (I) for treating congestive heart failure: (I) wherein: R1 and R2 are a variety of phenyl substituents, L is a divalent alkylene or amide containing alkylene linking group. Pharmaceutical composition, methods for their use in treating cardiovascular conditions, processes used in synthesis and intermediates used in such processes.

公开(公告)号：NZ234842A

公开(公告)日：1992-06-25

申请号：NZ23484290

申请日：1990-08-09

Applicant: GLAXO INC

Inventor： WHEELER THOMAS N ,  SHAFFER JOEL E ,  KENAKIN TERRENCE

IPC: A61K31/50 ,  A61P9/00 ,  A61P9/04 ,  C07D237/04

Abstract: Pyridazinones of the following formula (I): where R -R are a variety of substituents and L is a linking group, a pharmaceutical composition for treating congestive heart failure, novel intermediates, methods for such treatment and processes for preparing compounds of formula (I).

公开(公告)号：ZA9006296B

公开(公告)日：1991-06-26

申请号：ZA9006296

申请日：1990-08-09

Applicant: GLAXO INC

Inventor： WHEELER THOMAS N ,  THOMAS N WHEELER ,  SHAFFER JOEL E ,  JOEL E SHAFFER ,  KENAKIN TERRENCE ,  TERRENCE KENAKIN

IPC: A61K20060101 ,  C07D20060101 ,  C07D ,  A61K

公开(公告)号：AU6310090A

公开(公告)日：1991-03-28

申请号：AU6310090

申请日：1990-09-21

Applicant: GLAXO INC

Inventor： WHEELER THOMAS N ,  SHAFFER JOEL E ,  KENAKIN TERRENCE

IPC: A61K31/44 ,  A61K31/4418 ,  A61P9/00 ,  C07D213/85 ,  A61K31/535

公开(公告)号：AU6081690A

公开(公告)日：1991-02-14

申请号：AU6081690

申请日：1990-08-09

Applicant: GLAXO INC

Inventor： WHEELER THOMAS N ,  SHAFFER JOEL E ,  KENAKIN TERRENCE

IPC: A61K31/50 ,  A61P9/00 ,  A61P9/04 ,  C07D237/04 ,  A61K31/535

Abstract: Pyridazinones of the following formula (I): where R -R are a variety of substituents and L is a linking group, a pharmaceutical composition for treating congestive heart failure, novel intermediates, methods for such treatment and processes for preparing compounds of formula (I).

公开(公告)号：ZA9007573B

公开(公告)日：1991-09-25

申请号：ZA9007573

申请日：1990-09-21

Applicant: GLAXO INC

Inventor： WHEELER THOMAS N ,  THOMAS N WHEELER ,  SHAFFER JOEL E ,  JOEL E SHAFFER ,  KENAKIN TERRENCE ,  TERRENCE KENAKIN

IPC: A61K20060101 ,  C07D20060101 ,  C07D ,  A61K

公开(公告)号：ZA906296B

公开(公告)日：1991-06-26

申请号：ZA906296

申请日：1990-08-09

Applicant: GLAXO INC

Inventor： WHEELER THOMAS N ,  THOMAS N WHEELER ,  SHAFFER JOEL E ,  JOEL E SHAFFER ,  KENAKIN TERRENCE ,  TERRENCE KENAKIN

IPC: A61K20060101 ,  C07D20060101 ,  C07D ,  A61K

公开(公告)号：CA2023026A1

公开(公告)日：1991-02-11

申请号：CA2023026

申请日：1990-08-09

Applicant: GLAXO INC

Inventor： WHEELER THOMAS N ,  SHAFFER JOEL E ,  KENAKIN TERRENCE

IPC: A61K31/50 ,  A61P9/00 ,  A61P9/04 ,  C07D237/04 ,  C07D413/12 ,  A61K31/535

Abstract: Pyridazinones of the following formula (I): (I) where R1-R4 are a variety of substituents and L is a linking group, a pharmaceutical composition for treating congestive heart failure, novel intermediates, methods for such treatment and processes for preparing compounds of formula (I).