公开(公告)号：AU7839694A

公开(公告)日：1995-04-10

申请号：AU7839694

申请日：1994-09-20

Applicant: GLAXO INC

Inventor： FELDMAN PAUL LAWRENCE ,  STAFFORD JEFFREY ALAN

IPC: C07D403/06 ,  A61K31/40 ,  A61K31/4025 ,  A61K31/415 ,  A61P25/00 ,  A61P29/00 ,  A61P43/00 ,  C07D207/08 ,  C07D207/10 ,  C07D207/14 ,  C07D207/16 ,  C07D405/06

Abstract: Novel pyrrolidine compounds which are useful for inhibiting the function of Type IV phosphodiesterase (PDE-IV) as well as methods for making the same are disclosed. Applications in treating inflammatory diseases and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, are also disclosed.