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1.发明授权3alpha-hydroxy-delta4-steroids of the pregnane series and esters thereof 失效PREGNANE系列和其中的3ALPHA-羟基-D-四唑类
公开(公告)号：US3825565A
公开(公告)日：1974-07-23
申请号：US19491871
申请日：1971-11-02
Applicant: GLAXO LAB LTD
IPC: C07J7/00 , C07C169/32
CPC classification number: C07J7/00 , Y10S514/816
Abstract: 3A - HYDROXY-$4-STEROIDS AND 3A-ESTERS THEREOF HAVING AN ACETYL GROUP IN THE B-CONFIGURATION AND A HYDROGEN ATOM IN THE A-CONFIGURATION AT THE 17-POSITION AND EITHER TWO HYDROGEN ATOMS OR A KETO GROUP AT THE 11-POSITION. THE DISCLOSED COMPOUNDS WITH CARRIERS OR EXCIPIENTS TO PROVIDE COMPOSITIONS HAVING MARKED ANAESTHETIC PROPERTIES.
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2.发明授权Novel 21-acyloxy-3alpha-hydroxy-5alpha-pregnone-11,20-diones 失效新型21-氰基-3ALPHA-羟基-5ALPHA-PREGNONE-11,20-DIONES
公开(公告)号：US3763195A
公开(公告)日：1973-10-02
申请号：US3763195D
申请日：1971-02-09
Applicant: GLAXO LAB LTD
IPC: C07J5/00 , C07J75/00 , C07C169/32
CPC classification number: C07J5/00 , C07J75/00 , Y10S514/822
Abstract: THIS INVENTION IS CONCERNED WITH IMPROVEMENTS IN OR RELATING TO PHARMACEUTICAL PREPARATIONS HAVING ANAESTHETIC ACTIVITY, AND MORE PARTICULARLY AQUEOUS PREPARATIONS SUITABLE FOR INTRAVENOUS INJECTION.
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公开(公告)号：US3821206A
公开(公告)日：1974-06-28
申请号：US10818971
申请日：1971-01-20
Applicant: GLAXO LAB LTD
IPC: C07D501/04 , C07D501/38 , C07D99/24
CPC classification number: C07D501/04 , C07D501/38
Abstract: The invention is concerned with the reaction of 1,3dipolarophiles, e.g., dicyanoacetylene, with derivatives of 7aminocephalosporanic acid containing an azido group. The resultant compounds contain a polyazole ring substituent and are of value as antibiotics or as intermediates for the production of antibiotics.
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公开(公告)号：ZA767496B
公开(公告)日：1978-02-22
申请号：ZA767496
申请日：1976-12-17
Applicant: GLAXO LAB LTD
IPC: A61K31/43 , A61K31/545 , A61P31/04 , C07D503/00 , C07C
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公开(公告)号：ZA7603635B
公开(公告)日：1977-05-25
申请号：ZA7603635
申请日：1976-06-18
Applicant: GLAXO LAB LTD
IPC: A61K31/545 , A61K31/546 , A61P31/04 , C07D307/54 , C07D333/24 , C07D501/20 , C07D501/26 , C07C , A61K
CPC classification number: C07D501/20 , C07D307/54 , C07D333/24
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Patent Agency Ranking
公开(公告)号：ZA747726B
公开(公告)日：1975-12-31
申请号：ZA747726
申请日：1974-12-04
Applicant: GLAXO LAB LTD
IPC: C07D307/46 , C07D307/54 , C07D333/22 , C07D333/24 , C07D499/00 , C07D499/44 , C07D499/46 , C07D501/20 , C07D501/30 , C07D501/36 , C07D501/42 , C07D501/57 , C07C
Abstract: Novel antibiotic compounds which are 7 beta -acrylamidoceph-3-em-4-carboxylic acids, and 6 beta -acrylamidopenam-3-carboxylic acids and non-toxic derivatives thereof wherein the acrylamido group has the structure wherein A is aryl group and B is a substituted or unsubstituted lower alkyl, lower alkenyl or lower alkynyl group; or an aryl, cycloalkyl or cycloalkenyl group. These compounds possess antibacterial activity against gram-positive and gram-negative organisms coupled with stability to beta -lactamases. The invention further relates to the administration of the compounds.
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公开(公告)号：ZA734593B
公开(公告)日：1974-06-26
申请号：ZA734593
申请日：1973-07-06
Applicant: GLAXO LAB LTD
IPC: A61K20060101 , A61K31/43 , A61K31/545 , C07C20060101 , C07D20060101 , C07D499/44 , C07D499/54 , C07D499/64 , C07D499/70 , C07D501/00 , C07D501/20 , C07D501/24 , C07D501/34 , C07D501/36 , C07D501/46 , C07C
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公开(公告)号：ZA723223B
公开(公告)日：1973-02-28
申请号：ZA723223
申请日：1972-05-12
Applicant: GLAXO LAB LTD
Inventor： COOK M , GREGORY G , BRADSHAW J
IPC: C07C271/14 , C07D213/55 , C07D307/42 , C07D307/54 , C07D307/79 , C07D307/81 , C07D333/16 , C07D333/24 , C07D333/60 , C07D499/00 , C07D499/64 , C07D
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公开(公告)号：ZA7003861B
公开(公告)日：1971-02-24
申请号：ZA7003861
申请日：1970-06-08
Applicant: GLAXO LAB LTD
CPC classification number: A61K31/573 , A61K31/16 , A61K31/57 , C07J5/00
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公开(公告)号：ZA7002941B
公开(公告)日：1971-01-27
申请号：ZA7002941
申请日：1970-04-30
Applicant: GLAXO LAB LTD
IPC: C07D213/64 , C07D213/643 , C07D213/73 , C07D491/048 , C07D
CPC classification number: C07D213/643 , C07D213/73
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