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1.发明授权17-acylates of 9alpha-fluoro-11beta, 17alpha-dihydroxy-16-methyl-1, 4-pregnadiene-3, 20-dione and corresponding-11-keto steroids and pharmaceutical compositions thereof 失效9α-氟-11beta，17α-二羟基-16-甲基-1,4-孕二烯-3,20-二酮和相应的11-酮类固醇的17-酰化物及其药物组合物
公开(公告)号：US3376193A
公开(公告)日：1968-04-02
申请号：US46643465
申请日：1965-06-23
Applicant: GLAXO LAB LTD
Inventor： JOSEPH ELKS , JOAN BAILEY ESME
CPC classification number: A61K9/0019 , A61K41/0019
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2.发明授权Method for introducing an oxygen function into a steroid molecule containing an enol group and compounds thereof 失效将氧功能引入含有烯醇基的类固醇分子的方法及其化合物
公开(公告)号：US3056809A
公开(公告)日：1962-10-02
申请号：US6694160
申请日：1960-11-04
Applicant: GLAXO LAB LTD
Inventor： RICHARD BARTON DEREK HAROLD , JOAN BAILEY ESME
IPC: C07J75/00
CPC classification number: C07J75/00
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公开(公告)号：DE1518915A1
公开(公告)日：1969-08-14
申请号：DE1518915
申请日：1965-01-28
Applicant: GLAXO LAB LTD
Inventor： ELKS JOSEPH , JOAN BAILEY ESME
IPC: A61K9/00 , A61K41/00 , C07C169/34
Abstract: (A) Cpds. of general formula I (I) X = beta-OH or keto R = (1-3C) st. chain alkyl opt. with a Me branch (B) Pharmaceutical preparations contg. (I). Topical anti-inflammatory. Preparations cont. 0.0001-5% I, opt. tog. with a bactericide, and may be in the form of lotions, powders, drops, suppositories, pills, tablets for chewing or sucking, aerosols, ointments, or creams.
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