公开(公告)号：JP2010204120A

公开(公告)日：2010-09-16

申请号：JP2010129736

申请日：2010-06-07

Applicant: Guava Technologies Inc ,  グアヴァ テクノロジーズ インコーポレイテッド

Inventor： DANIELZADEH ROBERT ,  OLSON KEITH R

IPC: G01N33/543 ,  C12Q1/68 ,  C12Q1/70 ,  G01N21/64 ,  G01N33/53 ,  G01N33/569 ,  G01N33/58 ,  G01N33/68 ,  G01N33/74

CPC classification number: G01N33/54306 ,  G01N33/54366 ,  G01N33/569 ,  G01N33/56983 ,  G01N33/582 ,  G01N33/585 ,  G01N33/6863 ,  G01N33/74

Abstract: PROBLEM TO BE SOLVED: To provide a composition and method for analyzing a certain sample to determine existence of one or more kinds of target specimens. SOLUTION: The method for detecting the target specimen includes (a) a process of inhibiting coupling between an antibody and the target specimen with a microparticle containing competitive inhibitor of this target specimen, and (b) a process of measuring the antibody coupled with the competitive inhibitor and detecting the target specimen when the microparticle passes a micro capillary cytometer optically coupled to a fluorescent light emitting device. COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：提供用于分析某一样品以确定一种或多种目标样品的存在的组合物和方法。 检测靶标的方法包括：（a）使用该目标标本的含有竞争性抑制剂的微粒抑制抗体与靶标本体的结合的方法，（b）测定抗体偶联 与竞争性抑制剂并且当微粒通过光学耦合到荧光发光器件的微毛细血管细胞仪时检测靶标本。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：CA2539452A1

公开(公告)日：2005-03-31

申请号：CA2539452

申请日：2004-09-17

Applicant: GUAVA TECHNOLOGIES INC

Inventor： DANIELZADEH ROBERT ,  OLSON KEITH R

IPC: G01N33/566 ,  C12Q1/68 ,  C12Q1/70 ,  G01N33/53 ,  G01N33/569 ,  G01N33/58 ,  G01N33/68 ,  G01N33/74

Abstract: A method of detecting first and second analytes includes providing a mixture containing first analytes and second analytes; adding microparticles of a first size coated with first competitive inhibitors that compete with the first analytes for binding to first antibodies to the first analytes, and adding microparticles of a second size coated with second competitive inhibitors that compete with the second analytes for binding to first antibodies to the second analytes, adding second antibodies specific to the first antibodies to the first analytes and second antibodies specific to the first antibodies to the second analytes, wherein the second antibodies specific to the first antibodies to the first analytes are labeled with a first fluorescent moiety, and the second antibodies specific to the first antibodies to the second analytes are labeled with a second fluorescent moiety

公开(公告)号：CA2539452C

公开(公告)日：2013-10-29

申请号：CA2539452

申请日：2004-09-17

Applicant: GUAVA TECHNOLOGIES INC

Inventor： DANIELZADEH ROBERT ,  OLSON KEITH R

IPC: G01N33/566 ,  C12Q1/68 ,  C12Q1/70 ,  G01N33/53 ,  G01N33/569 ,  G01N33/58 ,  G01N33/68 ,  G01N33/74

Abstract: Compositions and methods are provided for analyzing a sample for the presence or absence of one or more target analytes.