公开(公告)号：WO1997027807A1

公开(公告)日：1997-08-07

申请号：PCT/US1997001127

申请日：1997-01-24

Applicant: HEARTPORT, INC.

Inventor： HEARTPORT, INC. ,  DANIEL, S., Christopher ,  DONLON, Brian, S. ,  GARRISON, Michi, E. ,  GIFFORD, Hansen, S., III ,  ROSENMAN, Daniel, C. ,  PETERS, William, S. ,  LATHROP, Robert, L., II ,  CROTHALL, George ,  MULLIN, James, B. ,  ANDERSON, Gerald, R. ,  KITTRELL, Wiley, A.

IPC: A61B17/04

CPC classification number: A61B17/0491 ,  A61B17/0469 ,  A61B17/062 ,  A61B17/0625 ,  A61B2017/047 ,  A61B2017/0472 ,  A61B2017/061 ,  A61F2/2409

Abstract: The invention provides devices and methods for suture placement while performing less invasive surgical procedures within a body cavity. In an exemplary embodiment, the invention provides for the placement of sutures (24) within the heart (H) or a great vessel that is accessed from outside the closed chest. According to one exemplary method, the patient's heart valve is accessed through an intercostal port (56) in the patient's chest. At least, one needle (26) having a suture (24) is then directed into the annulus while visualizing through the port placement (56) of the needle into the annulus. The needle (26) is then passed through the annulus.

Abstract translation: 本发明提供了用于缝合放置的装置和方法，同时在体腔内执行较少侵入性的外科手术。 在一个示例性实施例中，本发明提供将缝合线（24）放置在心脏（H）内或从封闭的胸部外部进入的大血管。 根据一个示例性方法，患者的心脏瓣膜通过患者胸部的肋间端口（56）进入。 至少，具有缝合线（24）的一个针（26）然后被引导到环形空间中，同时通过针的端口放置（56）可视化成环形空间。 针（26）然后穿过环。

公开(公告)号：WO1997027799A1

公开(公告)日：1997-08-07

申请号：PCT/US1997001018

申请日：1997-01-23

Applicant: HEARTPORT, INC.

Inventor： HEARTPORT, INC. ,  DONLON, Brian, S. ,  PETERS, William, S. ,  GARRISON, Michi, E. ,  ROSENMAN, Daniel, C. ,  STEVENS, John, H.

IPC: A61B05/00

CPC classification number: A61B17/00234 ,  A61B17/0057 ,  A61B17/0218 ,  A61B17/0293 ,  A61B17/0467 ,  A61B17/0469 ,  A61B17/06061 ,  A61B17/122 ,  A61B17/29 ,  A61B17/2909 ,  A61B17/3417 ,  A61B17/3421 ,  A61B18/1492 ,  A61B90/36 ,  A61B90/50 ,  A61B2017/00053 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00278 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/00907 ,  A61B2017/00946 ,  A61B2017/0237 ,  A61B2017/0243 ,  A61B2017/047 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/0496 ,  A61B2017/2912 ,  A61B2017/2926 ,  A61B2017/2927 ,  A61B2017/2932 ,  A61B2017/2943 ,  A61B2017/306 ,  A61B2017/308 ,  A61B2017/3405 ,  A61B2017/3492 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00291 ,  A61B2018/00363 ,  A61B2018/00392 ,  A61B2018/00577 ,  A61B2018/00982 ,  A61B2090/061 ,  A61B2090/306 ,  A61F2/2427 ,  A61F2/2496 ,  A61F7/10 ,  A61F2007/0001 ,  A61F2007/0054 ,  A61F2007/101 ,  A61M1/3621 ,  A61M25/1011 ,  A61M39/0247 ,  A61M2025/028 ,  A61M2039/027 ,  A61M2039/0279 ,  A61M2202/047 ,  A61M2205/3344 ,  A61M2205/3355 ,  A61M2205/366 ,  Y10S623/902

Abstract: Systems and methods are disclosed for performing less invasive surgical procedures within the heart. A method for less invasive repair or replacement of a cardiac valve (216) comprises placing an instrument (290) through an intercostal access port (212) and through a penetration in a wall of a vessel in communication with the heart, advancing the instrument (290) into the heart, using the instrument (290) to perform a surgical intervention on a cardiac valve (216) in the heart under visualization through an intercostal access port. The surgeons hands are kept outside of the chest during each step. The surgical intervention may comprise replacing the cardiac valve with a prosthetic valve, wherein the native valve is removed using a tissue removal instrument (206), the native valve annulus is sized with a specialized sizing device (216), a prosthetic valve is introduced through an intercostal access port (212) and through the penetration in the vessel, and the prosthetic valve is secured at the native valve position, all using instruments positioned through intercostal access ports without placing the hands inside the chest. Systems and devices for performing these procedures are also disclosed.

Abstract translation: 公开了用于在心脏内执行较少侵入性外科手术的系统和方法。 用于较少侵入性修复或更换心脏瓣膜（216）的方法包括将器械（290）穿过肋间进入口（212）并通过与心脏连通的血管壁穿透，推进器械 290）进入心脏，使用仪器（290）通过肋间进入端口在可视化的心脏内的心脏瓣膜（216）上执行手术干预。 在每一步中，外科医生的手都保持在胸前。 外科手术可以包括用假性瓣膜替换心脏瓣膜，其中使用组织去除器具（206）去除所述天然瓣膜，所述天然瓣膜通过专门的上浆装置（216）来定尺寸，通过引入人工瓣膜 肋间进入口（212），并穿过容器内的穿透，并且人造瓣膜固定在天然瓣膜位置，所有这些都使用通过肋间进入口定位的器械，而不将手放在胸部内。 还公开了用于执行这些程序的系统和装置。

公开(公告)号：WO1998003213A1

公开(公告)日：1998-01-29

申请号：PCT/US1997012934

申请日：1997-07-23

Applicant: HEARTPORT, INC.

Inventor： HEARTPORT, INC. ,  STEVENS, John, H. ,  BOLDUC, Lee, R. ,  BOYD, Stephen, W. ,  GIFFORD, Hanson, S., III ,  DONLON, Brian, S. ,  HOULE, Philip, R. ,  ROSENMAN, Daniel, C.

IPC: A61M01/14

CPC classification number: A61B17/0057 ,  A61B17/00234 ,  A61B17/0218 ,  A61B17/0293 ,  A61B17/0467 ,  A61B17/0469 ,  A61B17/06061 ,  A61B17/122 ,  A61B17/29 ,  A61B17/2909 ,  A61B17/3421 ,  A61B18/1492 ,  A61B90/36 ,  A61B90/50 ,  A61B2017/00053 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/00907 ,  A61B2017/00946 ,  A61B2017/0237 ,  A61B2017/0243 ,  A61B2017/047 ,  A61B2017/0472 ,  A61B2017/0474 ,  A61B2017/0475 ,  A61B2017/0496 ,  A61B2017/2912 ,  A61B2017/2926 ,  A61B2017/2927 ,  A61B2017/2932 ,  A61B2017/2943 ,  A61B2017/306 ,  A61B2017/308 ,  A61B2017/3405 ,  A61B2017/3492 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00291 ,  A61B2018/00363 ,  A61B2018/00392 ,  A61B2018/00577 ,  A61B2018/00982 ,  A61B2090/061 ,  A61B2090/306 ,  A61F2/2442 ,  A61F2/2445 ,  A61F7/10 ,  A61F2007/0001 ,  A61F2007/0054 ,  A61F2007/101 ,  A61M1/3621 ,  A61M25/1011 ,  A61M39/0247 ,  A61M2025/028 ,  A61M2039/027 ,  A61M2039/0279 ,  A61M2202/047 ,  A61M2205/3344 ,  A61M2205/3355 ,  A61M2205/366

Abstract: A method of treatment of congestive heart failure comprises the steps of introducing an aortic occlusion catheter (26) through a patient's peripheral artery, the aortic occlusion catheter (26) having an occluding member (30) movable from a collapsed position to an expanded position; positioning the occluding member (30) in the patient's ascending aorta; moving the occluding member (30) from the collapsed shape to the expanded shape after the positioning step; introducing cardio-plegia fluid into the patient's coronary blood vessels to arrest the patient's heart; maintaining circulation of oxygenated blood through the patient's arterial system; and reshaping an outer wall of the patient's heart while the heart is arrested so as to reduce the transverse dimension of the left ventricle. The ascending aorta may be occluded and cardio-plegia fluid delivered by means of an occlusion balloon (44) attached to the distal end of an elongated catheter (42) positioned trans-luminal in the aorta from a femoral, subclavian, or other appropriate peripheral artery.

Abstract translation: 治疗充血性心力衰竭的方法包括以下步骤：将主动脉闭塞导管（26）引入患者的外周动脉，所述主动脉闭塞导管（26）具有可从折叠位置移动到扩张位置的闭塞构件（30） 将所述闭塞构件（30）定位在患者的升主动脉中; 在定位步骤之后将封闭构件（30）从折叠形状移动到扩展形状; 将心血管流体引入患者的冠状动脉血管以阻止患者的心脏; 维持氧合血液循环通过病人的动脉系统; 并在心脏被逮住时重塑患者心脏的外壁，以减小左心室的横向尺寸。 上升主动脉可以闭塞，并且通过附接到细长导管（42）的远端的闭塞气囊（44）递送的心脏 - 血液流体，其从主动脉在大腿，锁骨下或其他适当的周边 动脉。

公开(公告)号：WO1997041801A1

公开(公告)日：1997-11-13

申请号：PCT/US1997007782

申请日：1997-05-07

Applicant: HEARTPORT, INC.

Inventor： HEARTPORT, INC. ,  ROSENMAN, Daniel, C. ,  GARRISON, Michi, E. ,  DANIEL, Sean, Christopher

IPC: A61F02/00

CPC classification number: A61F2/2496 ,  Y10S623/90

Abstract: A valve sizer (2) having a movable element mounted to the distal end of a shaft (4). A valve sizing portion includes the movable element (8) so that the valve sizing portion may be adjusted to correspond to a number of different available replacement valve sizes. An indicator (32) mounted to the proximal end of the shaft (4) indicates the valve size corresponding to the outer dimension of the valve sizing portion.

Abstract translation: 一种具有安装到轴（4）的远端的可移动元件的阀门分级器（2）。 阀门尺寸部分包括可移动元件（8），使得阀门施胶部分可以被调节以对应于多个不同的可用替换阀尺寸。 安装到轴（4）的近端的指示器（32）指示对应于阀门尺寸部分的外部尺寸的阀门尺寸。

公开(公告)号：EP0983015A2

公开(公告)日：2000-03-08

申请号：EP99903285.7

申请日：1999-01-22

Applicant: HEARTPORT, INC.

Inventor： GRIMES, Kevin, V. ,  KOMTEBEDDE, Jan ,  ROSENMAN, Daniel, C. ,  GIFFORD, Hanson, S., III ,  GARRISON, Michi, E. ,  STERMAN, Wesley, D. ,  TAYLOR, David, M. ,  SHARKAWY, A., Adam ,  RAY, Pinaki

IPC: A61B1/00

CPC classification number: A61B17/3417 ,  A61B17/0206 ,  A61B17/3421 ,  A61B2017/00243 ,  A61M25/10 ,  A61M25/1002 ,  A61M2025/1052 ,  A61M2025/1084 ,  A61M2210/127

Abstract: This invention is a method, and device for occluding a patient's ascending aorta, maintaining circulation of oxygenated blood (72) in the patient, and delivering cardio-plegia fluid (64) to arrest the patient's heart. An aortic occlusion catheter has an occluding member (4) for occluding the ascending aorta. The aortic occlusion catheter (2) passes through a cannula (28). Delivery of oxygenated blood (72) is accomplished through either the cannula (28) or the aortic occlusion catheter (2). In another aspect of the invention, an arterial cannula (28) has a curved or angled distal portion (40). An introducer (50) straightens the distal portion (40) for introduction into the patient. In still another aspect of the invention, an open-mesh stabilizer (172) is used to stabilize a discoid occluding member (4K).

公开(公告)号：EP0983015B1

公开(公告)日：2005-03-16

申请号：EP99903285.7

申请日：1999-01-22

Applicant: HEARTPORT, INC.

Inventor： GRIMES, Kevin, V. ,  KOMTEBEDDE, Jan ,  ROSENMAN, Daniel, C. ,  GIFFORD, Hanson, S., III ,  GARRISON, Michi, E. ,  STERMAN, Wesley, D. ,  TAYLOR, David, M. ,  SHARKAWY, A., Adam ,  RAY, Pinaki

IPC: A61B1/00

CPC classification number: A61B17/3417 ,  A61B17/0206 ,  A61B17/3421 ,  A61B2017/00243 ,  A61M25/10 ,  A61M25/1002 ,  A61M2025/1052 ,  A61M2025/1084 ,  A61M2210/127

Abstract: A method and device for occluding a patient's ascending aorta, maintaining circulation of oxygenated blood in the patient and delivering cardioplegic fluid to arrest the patient's heart. An aortic occlusion catheter has an occluding member for occluding the ascending aorta. The aortic occlusion catheter passes through a cannula. Delivery of oxygenated blood is accomplished through either the cannula or the aortic occlusion catheter. In another aspect of the invention, an arterial cannula having a curved or angled distal portion. An introducer straightens the distal portion for introduction into the patient. In still another aspect of the invention, an open-mesh stabilizer is used to stabilize a discoid occluding member.