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公开(公告)号:US20230280262A1
公开(公告)日:2023-09-07
申请号:US18023718
申请日:2020-09-09
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Viktor Shkolnikov , Joshua M. Yu , Matthew David Smith , Roberto A. Pugliese
IPC: G01N15/14
CPC classification number: G01N15/1484 , G01N15/1429
Abstract: In one example in accordance with the present disclosure, a particle detection system is described. The particle detection system includes a microfluidic channel through which fluid is to flow. The fluid includes particles. The particle detection system also includes a sensing circuit to output a resonant frequency. The sensing circuit includes a pair of electrodes disposed within the microfluidic channel. Contents of a volume between the pair of electrodes changes a capacitance between the pair of electrodes. A change in the capacitance changes the resonant frequency output by the sensing circuit. The particle detection system also includes a controller to determine the contents of the volume based on the resonant frequency.
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公开(公告)号:US20180222109A1
公开(公告)日:2018-08-09
申请号:US15748846
申请日:2015-10-20
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: David H. Ochs , Joshua M. Yu , Jeffrey A. Nielsen , Kenneth Ward , Christie Dudenhoefer
IPC: B29C64/112 , B29C64/386 , B29C64/40 , B29C64/188
CPC classification number: B29C64/112 , B29C64/188 , B29C64/245 , B29C64/386 , B29C64/40 , B33Y10/00 , B33Y30/00 , B33Y50/02
Abstract: Systems, methods, and computer readable medium to provide patterned layer deposition of liquid types to a plate surface in layers organized in layouts with sites of patterns aligned to a plate origin of the plate surface. At least one layer includes a layout defining a geometric layout of the plate surface.
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公开(公告)号:US20180008979A1
公开(公告)日:2018-01-11
申请号:US15545377
申请日:2015-06-29
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Joshua M. Yu , Matthew David Smith , Shameed Sait M A , Manish Giri
CPC classification number: B01L3/502715 , B01L3/50273 , B01L7/00 , B01L2200/147 , B01L2300/0627 , B01L2300/0645 , B01L2300/0816 , B01L2300/1827 , B01L2400/0442 , G01N15/0266 , G01N15/1404 , G01N15/1459 , G01N15/1484 , G01N2015/0065 , G01N2015/1006 , G01N2015/1486 , G01N2015/1493 , H05B1/025
Abstract: Fluid may be pumped within a microfluidic channel across a cell/particle sensor using a microscopic resistor. The microscopic resistor may be selectively actuated so as to heat the fluid within the microfluidic channel to a temperature below a nucleation energy of the fluid so as to regulate a temperature of the fluid for at least when the cell/particle sensor is sensing the fluid.
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公开(公告)号:US11097272B2
公开(公告)日:2021-08-24
申请号:US16099172
申请日:2016-07-26
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Chantelle Domingue , Tod Woodford , Manish Giri , Matthew David Smith , George H Corrigan, III , Masoud Zavarehi , Joshua M. Yu
Abstract: According to an example, a microfluidic apparatus may include a fluid slot and a foyer that is in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer. The microfluidic apparatus may also include an electrical sensor to measure a change in an electrical field caused by a particle of interest in a fluid passing through the channel from the fluid slot to the foyer, an actuator to apply pressure onto fluid contained in the foyer, and a controller to receive the measured change in the electrical field from the electrical sensor, determine, from the received change in the electrical field, an electrical signature of the particle of interest, and control the actuator to control movement of the particle of interest based upon the determined electrical signature of the particle of interest.
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公开(公告)号:US20250012703A1
公开(公告)日:2025-01-09
申请号:US18702172
申请日:2021-10-29
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Yang Lei , Joshua M. Yu , Timothy Merritt Holt , Angela Bakkom
IPC: G01N15/1031 , G01N15/01 , G06V20/69
Abstract: A non-limiting example method for control of fluid ejection from a microfluidic device includes firing a microfluidic ejector of a microfluidic device to expel a fluid from a channel of the microfluidic device. In response to detecting an instance of signal change from an impedance sensor disposed in the channel, the method includes controlling fluid ejection from the microfluidic ejector and capturing an image of the channel with an imaging apparatus. Using the captured image, a determination is made as to whether passage of a cell into the channel is associated with the instance of signal change from the impedance sensor. Based on the determination, the microfluidic ejector may fire to dispense the fluid from the channel into a reservoir.
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公开(公告)号:USD1022931S1
公开(公告)日:2024-04-16
申请号:US29801988
申请日:2021-08-02
Applicant: Hewlett-Packard Development Company, L.P.
Designer: Vignesh Kannan , Joshua M. Yu , Matthew David Smith , Jeffrey A. Nielsen , Kenneth Duda
Abstract: FIG. 1 is perspective view, taken from a front, lower-right elevation of a sensing and dispensing integrated circuit;
FIG. 2 is a front plan view of the sensing and dispensing integrated circuit shown in FIG. 1;
FIG. 3 is a back plan view of the sensing and dispensing integrated circuit shown in FIG. 1;
FIG. 4 is a right side plan view of the sensing and dispensing integrated circuit shown in FIG. 1;
FIG. 5 is a left side plan view of the sensing and dispensing integrated circuit shown in FIG. 1;
FIG. 6 is a top plan view of the sensing and dispensing integrated circuit shown in FIG. 1; and,
FIG. 7 is a bottom plan view of the sensing and dispensing integrated circuit shown in FIG. 1.
Broken lines shown in the drawings represent portions of the integrated flex circuit that form no part of the claimed design.-
公开(公告)号:US11007529B2
公开(公告)日:2021-05-18
申请号:US16099658
申请日:2016-07-26
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Jeffrey A Nielsen , Manish Giri , Chantelle Domingue , Kenneth Ward , Christie Dudenhoefer , Matthew David Smith , Joshua M. Yu , Hilary Ely
Abstract: According to an example, a microfluidic apparatus may include a fluid slot, a foyer in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer, a sensor to detect a presence of a particle of interest in a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to receive information from the sensor, determine, from the received information, whether a particle of interest has passed through the channel, and control the actuator to expel fluid in the foyer through the nozzle based upon the determination.
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公开(公告)号:US20170341076A1
公开(公告)日:2017-11-30
申请号:US15521230
申请日:2015-06-29
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Joshua M. Yu , Matthew David Smith , Shameed Sait M A , Manish Giri
IPC: B01L3/00 , G01N35/00 , G01N33/487
CPC classification number: B01L3/502715 , B01L2200/14 , B01L2200/147 , B01L2200/148 , B01L2400/0487 , G01N33/48792 , G01N35/00871 , G16H10/40
Abstract: Example implementations relate to a microfluidics sensing system. For example, a microfluidics sensing system may include a portable computing device to execute a microfluidics application, a microfluidic chip coupled to the portable computing device, the microfluidic chip including a microfluidic pumping and sensing region to perform a test on a biologic sample, and a printed circuit board (PCB) on a microfluidic reader to instruct the microfluidic pumping and sensing region to perform the test based on a command received from the microfluidics application.
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公开(公告)号:US11203017B2
公开(公告)日:2021-12-21
申请号:US16099668
申请日:2016-07-26
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Jeffrey A Nielsen , Manish Giri , Chantelle Domingue , Kenneth Ward , Christie Dudenhoefer , Matthew David Smith , Joshua M. Yu , Diane R. Hammerstad , Hilary Ely
Abstract: According to an example, a microfluidic apparatus may include a channel, a foyer, in which the foyer is in fluid communication with the channel and in which the channel has a smaller width than the foyer, a sensor to sense a property of a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to determine whether the sensed property of the fluid meets a predetermined condition and to perform a predefined action in response to the sensed property of the fluid meeting the predetermined condition.
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公开(公告)号:US11179720B2
公开(公告)日:2021-11-23
申请号:US16319702
申请日:2016-10-07
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Manish Giri , Chantelle Domingue , Tod Woodford , Matthew David Smith , Rachel M. White , Joshua M. Yu , Hilary Ely , Jeremy Sells
Abstract: The present disclosure is drawn to microfluidic chips. The microfluidic chips can include an inflexible material having an elastic modulus of 0.1 gigapascals (GPa) to 450 GPa. A microfluidic channel can be formed within the inflexible material and can connect an inlet and an outlet. A working electrode can be associated with the microfluidic channel and can have a surface area of 1 μm2 to 60,000 μm2 within the microfluidic channel. A bubble support structure can also be formed within the microfluidic channel such that the working electrode is positioned to electrolytically generate a bubble that becomes associated with the bubble support structure.
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