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    MICROFLUIDIC CHIPS WITH PLASMONIC SENSORS
    3.
    发明申请
    MICROFLUIDIC CHIPS WITH PLASMONIC SENSORS 审中-公开

    公开(公告)号：WO2022025864A1

    公开(公告)日：2022-02-03

    申请号：PCT/US2020/043828

    申请日：2020-07-28

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： D'APUZZO, Fausto ,  SENGUPTA, Raghuvir N. ,  LIU, Albert ,  SHKOLNIKOV, Viktor

    IPC: C12Q1/04 ,  C12Q1/70 ,  C12M1/12 ,  C12M1/34 ,  G01N21/65 ,  B81B1/00 ,  B81B7/02

    Abstract: In example implementations, a microfluidic chip is provided. The microfluidic chip includes a first channel, a second channel, and a plasmonic sensor. The first channel includes a first antibiotic chamber and a first filter chamber. The first antibiotic chamber includes a first media and a first antibiotic that is rehydrated by a bacterial suspension and the first filter chamber is to filter bacteria from first metabolites released from the bacteria in response to incubation with a buffer solution. The second channel includes a second antibiotic chamber and a second filter chamber. The second antibiotic chamber includes a second media and a second antibiotic that is rehydrated by the bacterial suspension and the second filter chamber is to filter the bacteria from second metabolites released from the bacteria in response to incubation with the buffer solution. The first channel and the second channel pass over the plasmonic sensor. The plasmonic sensor is to measure an amount of the first metabolites and the second metabolites.

    FLUID DISPENSING FOR CALIBRATED PLASMONIC SENSING
    5.
    发明申请
    FLUID DISPENSING FOR CALIBRATED PLASMONIC SENSING 审中-公开

    公开(公告)号：WO2021225600A1

    公开(公告)日：2021-11-11

    申请号：PCT/US2020/032028

    申请日：2020-05-08

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： D'APUZZO, Fausto ,  SENGUPTA, Raghuvir N. ,  BARCELO, Steven ,  OVERBAY, Milo

    IPC: G01N1/38 ,  G01N21/65

    Abstract: Systems and methods for generating test spots for plasmonic sensing are disclosed. An example apparatus includes a first fluid ejection device coupled to a first fluid vessel, and a second fluid ejection device coupled to a second fluid vessel. The apparatus also includes a processor to control the first fluid ejection device to dispense colloidal nanoparticles from the first fluid vessel onto a testing location on a substrate, and control the second fluid ejection device to dispense a target analyte from the second fluid vessel onto the testing location to form a test mixture.

    ORDERED ARRAYS OF MICRODOTS
    7.
    发明申请
    ORDERED ARRAYS OF MICRODOTS 审中-公开

    公开(公告)号：WO2020131036A1

    公开(公告)日：2020-06-25

    申请号：PCT/US2018/066245

    申请日：2018-12-18

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： D'APUZZO, Fausto ,  BARCELO, Steven ,  SENGUPTA, Raghuvir N.

    IPC: G01N21/62

    Abstract: In an example method, an ordered array of microdots including an analyte printed on a surface of a surface-enhanced substrate of an analysis chip is probed with an excitation beam of electromagnetic radiation. Emitted radiation is detected from a number of microdots of the ordered array of microdots. Calibration data is generated for the analysis chip with respect to the analyte based on a detected shift in the emitted radiation as compared to the excitation beam.

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