公开(公告)号：AU2014217108A1

公开(公告)日：2015-08-27

申请号：AU2014217108

申请日：2014-02-12

Applicant: HISAMITSU PHARMACEUTICAL CO ,  CHEMO SERO THERAPEUT RES INST

Inventor： MACHIDA KAZUYA ,  TOKUMOTO SEIJI ,  KAMINAKA KAZUYOSHI ,  ISHIKAWA YUJI

IPC: A61K47/18 ,  A61K9/70 ,  A61K39/12 ,  A61K47/12 ,  A61P31/14

Abstract: Disclosed is a microneedle coating composition which includes a Japanese encephalitis vaccine antigen, a basic amino acid, and an acid, the number of moles of the acid relative to 1 mol of the basic amino acid being in the range of more than 1/(N+1) to less than 2 when N is the valence of the acid.

公开(公告)号：CA2900920A1

公开(公告)日：2014-08-21

申请号：CA2900920

申请日：2014-02-12

Applicant: HISAMITSU PHARMACEUTICAL CO ,  CHEMO SERO THERAPEUT RES INST

Inventor： MACHIDA KAZUYA ,  TOKUMOTO SEIJI ,  KAMINAKA KAZUYOSHI ,  ISHIKAWA YUJI

IPC: A61K47/18 ,  A61K9/70 ,  A61K39/12 ,  A61K47/12 ,  A61P31/14

Abstract: Disclosed is a microneedle coating composition which includes a Japanese encephalitis vaccine antigen, a basic amino acid, and an acid, the number of moles of the acid relative to 1 mol of the basic amino acid being in the range of more than 1/(N+1) to less than 2 when N is the valence of the acid.

公开(公告)号：SG11201506326YA

公开(公告)日：2015-09-29

申请号：SG11201506326Y

申请日：2014-02-12

Applicant: HISAMITSU PHARMACEUTICAL CO ,  CHEMO SERO THERAPEUT RES INST

Inventor： MACHIDA KAZUYA ,  TOKUMOTO SEIJI ,  KAMINAKA KAZUYOSHI ,  ISHIKAWA YUJI

IPC: A61K47/18 ,  A61K9/70 ,  A61K39/12 ,  A61K47/12 ,  A61P31/14

Abstract: Disclosed is a microneedle coating composition comprising a Japanese encephalitis vaccine antigen, a basic amino acid, and an acid, wherein the mole number of the acid for one mole of the basic amino acid is larger than 1/(N+1) and less than 2, where N represents the valence of the acid.

公开(公告)号：PH12015501765B1

公开(公告)日：2015-11-09

申请号：PH12015501765

申请日：2015-08-12

Applicant: HISAMITSU PHARMACEUTICAL CO

Inventor： MACHIDA KAZUYA ,  TOKUMOTO SEIJI ,  KAMINAKA KAZUYOSHI ,  ISHIKAWA YUJI

IPC: A61K9/70 ,  A61K39/12 ,  A61K47/12 ,  A61K47/18 ,  A61P31/14

Abstract: Disclosed is a microneedle coating composition comprising a Japanese encephalitis vaccine antigen, a basic amino acid, and an acid, wherein the mole number of the acid for one mole of the basic amino acid is larger than 1/(N+1) and less than 2, where N represents the valence of the acid.

公开(公告)号：CA2900920C

公开(公告)日：2018-08-21

申请号：CA2900920

申请日：2014-02-12

Applicant: HISAMITSU PHARMACEUTICAL CO ,  THE CHEMO SERO THERAPEUTIC RES INSTITUTE

Inventor： MACHIDA KAZUYA ,  TOKUMOTO SEIJI ,  KAMINAKA KAZUYOSHI ,  ISHIKAWA YUJI

IPC: A61K47/18 ,  A61K9/70 ,  A61K39/12 ,  A61K47/12 ,  A61P31/14

Abstract: Disclosed is a microneedle coating composition comprising a Japanese encephalitis vaccine antigen, a basic amino acid, and an acid, wherein the mole number of the acid for one mole of the basic amino acid is larger than 1/(N+1) and less than 2, where N represents the valence of the acid.

公开(公告)号：AU2014217108B2

公开(公告)日：2017-06-15

申请号：AU2014217108

申请日：2014-02-12

Applicant: HISAMITSU PHARMACEUTICAL CO

Inventor： MACHIDA KAZUYA ,  TOKUMOTO SEIJI ,  KAMINAKA KAZUYOSHI ,  ISHIKAWA YUJI

IPC: A61K47/18 ,  A61K9/70 ,  A61K39/12 ,  A61K47/12 ,  A61P31/14

Abstract: Disclosed is a microneedle coating composition which includes a Japanese encephalitis vaccine antigen, a basic amino acid, and an acid, the number of moles of the acid relative to 1 mol of the basic amino acid being in the range of more than 1/(N+1) to less than 2 when N is the valence of the acid.

公开(公告)号：EP2957298A4

公开(公告)日：2016-09-14

申请号：EP14751836

申请日：2014-02-12

Applicant: HISAMITSU PHARMACEUTICAL CO

Inventor： MACHIDA KAZUYA ,  TOKUMOTO SEIJI ,  KAMINAKA KAZUYOSHI ,  ISHIKAWA YUJI

IPC: A61K47/18 ,  A61K9/70 ,  A61K39/12 ,  A61K47/12 ,  A61P31/14

CPC classification number: A61K39/12 ,  A61K9/0021 ,  A61K47/12 ,  A61K47/183 ,  A61K2039/54 ,  C12N7/00 ,  C12N2770/24134

Abstract: Disclosed is a microneedle coating composition comprising a Japanese encephalitis vaccine antigen, a basic amino acid, and an acid, wherein the mole number of the acid for one mole of the basic amino acid is larger than 1/(N+1) and less than 2, where N represents the valence of the acid.