公开(公告)号：EP2623960A4

公开(公告)日：2017-11-15

申请号：EP11828589

申请日：2011-07-21

Applicant: HITACHI HIGH-TECHNOLOGIES CORP

Inventor： OZAWA SATOSHI ,  ANAZAWA TAKASHI ,  AKAHORI RENA ,  TAKAHASHI SATOSHI ,  OHURA TAKESHI ,  KIGUCHI MASASHI

IPC: G01N21/65 ,  B82Y5/00 ,  B82Y15/00 ,  C12N15/09 ,  G01J3/02 ,  G01N33/487 ,  G01N37/00

CPC classification number: G01J3/0267 ,  B82Y5/00 ,  B82Y15/00 ,  C12Q1/6869 ,  G01N21/658 ,  G01N33/48721 ,  C12Q2565/631 ,  C12Q2565/632

Abstract: The present invention provides a device and method for analyzing the characteristics of a biopolymer with excellent mechanical stability, high spatial resolution and sensitivity using a simple device construction. Specifically, the Raman scattered light of a biopolymer is measured and the properties of monomer units forming the biopolymer are analyzed by using a biopolymer property analysis chip (100a) characterized by comprising: a solid substrate (110); at least one nanopore (120) disposed in the solid substrate (110); and one or more electrically conductive thin films (130a, 1 30b) disposed on the solid substrate (110). The biopolymer property analysis chip (100a) is characterized in that the electrically conductive thin films (130a,130b) are disposed partially on the solid substrate (110) where the nanopore (120) is formed and a biopolymer which has penetrated into the nanopore (120) is caused to generate Raman scattered light by means of irradiation with external light.