公开(公告)号：DK137640C

公开(公告)日：1978-10-09

申请号：DK445575

申请日：1975-10-02

Applicant: HOECHST AG

Inventor： PIETSCH H ,  CLAUSS K ,  JENSEN H ,  SCHMIDT E

IPC: C07C20060101 ,  C07C307/00 ,  C07C67/00 ,  C07C301/00 ,  C07C303/36 ,  C07D291/06 ,  C07C143/86

Abstract: 1476101 N-Fluorosulphonylacetoacetamide HOECHST AG 2 Oct 1975 [3 Oct 1974] 40314/75 Heading C2C N-Fluorosulphonylacetoacetamide is prepared by reacting sulphamoyl fluoride with diketene at 50-100‹ C., preferably in an inert solvent. It may be reacted with methanolic KOH to give 6-methyl-3,4-dihydro-1,2,3- oxathiazine-4-one-2,2-dioxide as the potassium salt.

公开(公告)号：DK445575A

公开(公告)日：1976-04-04

申请号：DK445575

申请日：1975-10-02

Applicant: HOECHST AG

Inventor： PIETSCH H ,  CLAUSS K ,  JENSEN H ,  SCHMIDT E

IPC: C07C20060101 ,  C07C307/00 ,  C07C67/00 ,  C07C301/00 ,  C07C303/36 ,  C07D291/06 ,  C07C

Abstract: 1476101 N-Fluorosulphonylacetoacetamide HOECHST AG 2 Oct 1975 [3 Oct 1974] 40314/75 Heading C2C N-Fluorosulphonylacetoacetamide is prepared by reacting sulphamoyl fluoride with diketene at 50-100‹ C., preferably in an inert solvent. It may be reacted with methanolic KOH to give 6-methyl-3,4-dihydro-1,2,3- oxathiazine-4-one-2,2-dioxide as the potassium salt.

公开(公告)号：DK137640B

公开(公告)日：1978-04-10

申请号：DK445575

申请日：1975-10-02

Applicant: HOECHST AG

Inventor： PIETSCH H ,  CLAUSS K ,  JENSEN H ,  SCHMIDT E

IPC: C07C20060101 ,  C07C307/00 ,  C07C67/00 ,  C07C301/00 ,  C07C303/36 ,  C07D291/06 ,  C07C143/86

Abstract: 1476101 N-Fluorosulphonylacetoacetamide HOECHST AG 2 Oct 1975 [3 Oct 1974] 40314/75 Heading C2C N-Fluorosulphonylacetoacetamide is prepared by reacting sulphamoyl fluoride with diketene at 50-100‹ C., preferably in an inert solvent. It may be reacted with methanolic KOH to give 6-methyl-3,4-dihydro-1,2,3- oxathiazine-4-one-2,2-dioxide as the potassium salt.

公开(公告)号：DK135992C

公开(公告)日：1978-01-02

申请号：DK326575

申请日：1975-07-17

Applicant: HOECHST AG

Inventor： CLAUSS K ,  PIETSCH H ,  SCHMIDT E ,  JENSEN H

IPC: A23L27/30 ,  C07D291/06 ,  C07D291/08

Abstract: 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide and the nontoxic salts thereof are prepared by reacting acetone and fluorosulfonyl isocyanate in a molar proportion of from 14:1 to 150:1 at a temperature of from 0 DEG to 60 DEG C, distilling off the excess acetone from the reaction mixture with acetoacetamide-N-sulfofluoride and bringing about cyclization by a treatment with bases at a pH of from 5 to 12. The oxathiazinone derivatives are used as sweeteners.

公开(公告)号：DK326775A

公开(公告)日：1976-01-19

申请号：DK326775

申请日：1975-07-17

Applicant: HOECHST AG

Inventor： CLAUSS K ,  SCHMIDT E ,  PIETSCH H ,  JENSEN H

IPC: A23L27/30 ,  C07D291/06 ,  C07D

公开(公告)号：DK135992B

公开(公告)日：1977-07-25

申请号：DK326575

申请日：1975-07-17

Applicant: HOECHST AG

Inventor： CLAUSS K ,  PIETSCH H ,  SCHMIDT E ,  JENSEN H

IPC: A23L27/30 ,  C07D291/06 ,  C07D291/08

Abstract: 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide and the nontoxic salts thereof are prepared by reacting acetone and fluorosulfonyl isocyanate in a molar proportion of from 14:1 to 150:1 at a temperature of from 0 DEG to 60 DEG C, distilling off the excess acetone from the reaction mixture with acetoacetamide-N-sulfofluoride and bringing about cyclization by a treatment with bases at a pH of from 5 to 12. The oxathiazinone derivatives are used as sweeteners.

公开(公告)号：DK326975A

公开(公告)日：1976-01-19

申请号：DK326975

申请日：1975-07-17

Applicant: HOECHST AG

Inventor： SCHMIDT E ,  CLAUSS K ,  PIETSCH ,  JENSEN H

IPC: C07C307/00 ,  C07C67/00 ,  C07C301/00 ,  C07C303/00 ,  C07D205/08 ,  C07D291/06 ,  C07C

Abstract: Compounds of the formula +q,10 IN WHICH R represents an alkyl radical having from 1 to 4 carbon atoms and Hal stands for fluorine or chlorine are prepared by reacting at a temperature of from -40 DEG to +20 DEG C an i-propenylalkanoic acid ester of the formula CH ¦ R-C(O)-O-C=CH2 (IV) with an isocyanate of the formula O=C=N-SO2Hal(V) in which R and Hal have the same meaning as above, and isolating the compound of formula III.

公开(公告)号：DK326875A

公开(公告)日：1976-01-19

申请号：DK326875

申请日：1975-07-17

Applicant: HOECHST AG

Inventor： SCHMIDT E ,  CLAUSS K ,  PIETSCH H ,  JENSEN H

IPC: A23L27/30 ,  C07D291/06 ,  C07D291/08 ,  C07D

Abstract: The potassium salt practically free of fluoride of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide is prepared by cyclization of acetoacetamide-N-sulfofluoride with at least two moles potassium hydroxide, potassium methylate or a mixture of potassium hydroxide and potassium methylate per mole of sulfofluoride in methanol as solvent containing less than 50 % by weight of water at a temperature of from -20 DEG to +60 DEG C and separating the crystalline potassium salt of the oxathiazinone dioxide from the reaction solution. The compound obtained has a pure sweet taste.

公开(公告)号：DK326675A

公开(公告)日：1976-01-19

申请号：DK326675

申请日：1975-07-17

Applicant: HOECHST AG

Inventor： PIETSCH H ,  CLAUSS K ,  SCHMIDT E ,  JENSEN H

IPC: A23L27/30 ,  C07D265/06 ,  C07D

公开(公告)号：DK326575A

公开(公告)日：1976-01-19

申请号：DK326575

申请日：1975-07-17

Applicant: HOECHST AG

Inventor： CLAUSS K ,  PIETSCH H ,  SCHMIDT E ,  JENSEN H

IPC: A23L27/30 ,  C07D291/06 ,  C07D291/08 ,  C07D

Abstract: 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide and the nontoxic salts thereof are prepared by reacting acetone and fluorosulfonyl isocyanate in a molar proportion of from 14:1 to 150:1 at a temperature of from 0 DEG to 60 DEG C, distilling off the excess acetone from the reaction mixture with acetoacetamide-N-sulfofluoride and bringing about cyclization by a treatment with bases at a pH of from 5 to 12. The oxathiazinone derivatives are used as sweeteners.