公开(公告)号：IE67652B1

公开(公告)日：1996-04-17

申请号：IE357990

申请日：1990-10-05

Applicant: HOECHST AG

Inventor： MUELLNER HUBERT ,  UHLMANN EUGEN ,  ECKES PETER ,  SCHNEIDER RUDOLF ,  UIJTEWAAL BERNADUS

IPC: A01H1/00 ,  A01H5/00 ,  A01N57/16 ,  A01N63/00 ,  C07H21/02 ,  C07H21/04 ,  C12N5/10 ,  C12N9/00 ,  C12N15/113 ,  C12N15/82 ,  C12N15/11

Abstract: Host cells can be transformed so that they express ribozyme RNA and antisense RNA which are connected together via a spacer. The RNA molecules can be complementary, for example, to a particular viral RNA. Plants which are transformed with genes coding for such RNA display a significantly improved defence against viruses.

公开(公告)号：CA2052808A1

公开(公告)日：1992-04-06

申请号：CA2052808

申请日：1991-10-04

Applicant: HOECHST AG

Inventor： ECKES PETER ,  SCHNEIDER RUDOLF

IPC: A61K36/00 ,  A61K38/00 ,  A61P31/12 ,  C12N5/00 ,  C12N5/10 ,  C12N9/22 ,  C12N15/00 ,  C12N15/09 ,  C12N15/10 ,  C12N15/55 ,  C12N15/79 ,  C12N15/82 ,  C12N15/29

Abstract: HOE 90/F 301 The invention relates to genes for the production of virus resistant plants. The gene encodes a sequence which can act as initiation sequence for the synthesis of a complementary RNA and which is subsequently coupled to an antisense sequence which allows a cap-independent translation in the sense orientation, and with an antisense sequence which encodes a protein which is destructive to the metabolism of a plant, in the sense orientation. After a virus has attacked the cell the RNA is transcribed into a complementary RNA by means of the viral replicase, or it is also possible that the RNA is transcribed into a complementary RNA by means of a replicase activated in the cell via a different mechanism and the information for a cell-destructive enzyme, which is now present in the sense orientation, is read off.

公开(公告)号：AU6382790A

公开(公告)日：1991-04-11

申请号：AU6382790

申请日：1990-10-05

Applicant: HOECHST AG

Inventor： MULLNER HUBERT ,  SCHNEIDER RUDOLF ,  UHLMANN EUGEN ,  UIJTEWAAL BERNARDUS ,  ECKES PETER

IPC: A01H1/00 ,  A01H5/00 ,  A01N57/16 ,  A01N63/00 ,  C07H21/02 ,  C07H21/04 ,  C12N5/10 ,  C12N9/00 ,  C12N15/113 ,  C12N15/82 ,  C12N15/11

Abstract: Host cells can be transformed so that they express ribozyme RNA and antisense RNA which are connected together via a spacer. The RNA molecules can be complementary, for example, to a particular viral RNA. Plants which are transformed with genes coding for such RNA display a significantly improved defence against viruses.

公开(公告)号：DK175800B1

公开(公告)日：2005-02-28

申请号：DK23988

申请日：1988-01-20

Applicant: HOECHST AG

Inventor： STRAUCH ECKHARD ,  ARNOLD WALTER ,  ALIJAH RENATE ,  WOHLLEBEN WOLFGANG ,  PUEHLER ALFRED ,  ECKES PETER ,  DONN GUENTER ,  UHLMANN EUGEN ,  HEIN FRIEDRICH ,  WENGENMAYER FRIEDRICH

IPC: A01H1/00 ,  A01H5/00 ,  C12N1/20 ,  C12N1/21 ,  C12N5/10 ,  C12N5/14 ,  C12N9/10 ,  C12N15/00 ,  C12N15/09 ,  C12N15/31 ,  C12N15/82 ,  C12R1/19 ,  C12R1/465

公开(公告)号：HU215079B

公开(公告)日：1998-09-28

申请号：HU21788

申请日：1988-01-20

Applicant: HOECHST AG

Inventor： ALIJAH RENATE ,  ARNOLD WALTER ,  DONN GUENTER ,  ECKES PETER ,  HEIN FRIEDRICH ,  PUEHLER ALFRED ,  STRAUCH ECKHARD ,  UHLMANN EUGEN ,  WENGENMAYER FRIEDRICH ,  WOHLLEBEN WOLFGANG

IPC: A01H1/00 ,  A01H5/00 ,  C12N1/20 ,  C12N1/21 ,  C12N5/10 ,  C12N5/14 ,  C12N9/10 ,  C12N15/00 ,  C12N15/09 ,  C12N15/31 ,  C12N15/82 ,  C12R1/19 ,  C12R1/465 ,  C12N15/54

公开(公告)号：IE67653B1

公开(公告)日：1996-04-17

申请号：IE382590

申请日：1990-10-24

Applicant: HOECHST AG

Inventor： MUELLNER HUBERT ,  SCHNEIDER RUDOLF ,  UHLMANN EUGEN ,  UIJTEWAAL BERNARDUS ,  ECKES PETER

IPC: A01H5/00 ,  A01H5/10 ,  A01N57/16 ,  A01N63/00 ,  A61K31/70 ,  A61P31/12 ,  C07H21/02 ,  C12N5/10 ,  C12N9/00 ,  C12N15/05 ,  C12N15/09 ,  C12N15/113 ,  C12N15/82 ,  C12N15/11

Abstract: Host cells can be transformed so that they express ribozyme RNA and antisense RNA, which are linked together in the loop of the ribozyme. The RNA molecules can, for example, be complementary to a particular viral RNA. Plants transformed with genes coding for such RNA display significantly improved defences against viruses.

公开(公告)号：IE903825A1

公开(公告)日：1991-05-08

申请号：IE382590

申请日：1990-10-24

Applicant: HOECHST AG

Inventor： MUELLNER HUBERT ,  SCHNEIDER RUDOLF ,  UHLMANN EUGEN ,  UIJTEWAAL BERNADUS ,  ECKES PETER

IPC: A01H5/00 ,  A01H5/10 ,  A01N57/16 ,  A01N63/00 ,  A61K31/70 ,  A61P31/12 ,  C07H21/02 ,  C12N5/10 ,  C12N9/00 ,  C12N15/05 ,  C12N15/09 ,  C12N15/113 ,  C12N15/82 ,  C12N15/11

Abstract: Host cells can be transformed so that they express ribozyme RNA and antisense RNA, which are linked together in the loop of the ribozyme. The RNA molecules can, for example, be complementary to a particular viral RNA. Plants transformed with genes coding for such RNA display significantly improved defences against viruses.

公开(公告)号：HUT47636A

公开(公告)日：1989-03-28

申请号：HU21788

申请日：1988-01-20

Applicant: HOECHST AG

Inventor： STRAUCH ECKHARD ,  ARNOLD WALTER ,  ALIJAH RENATE ,  WOHLLEBEN WOLFGANG ,  PUEHLER ALFRED ,  ECKES PETER ,  DONN GUENTER

IPC: A01H1/00 ,  A01H5/00 ,  C12N1/20 ,  C12N1/21 ,  C12N5/10 ,  C12N5/14 ,  C12N9/10 ,  C12N15/00 ,  C12N15/09 ,  C12N15/31 ,  C12N15/82 ,  C12R1/19 ,  C12R1/465 ,  C12N5/00 ,  C12P19/34

公开(公告)号：ZA883947B

公开(公告)日：1989-02-22

申请号：ZA883947

申请日：1988-06-03

Applicant: HOECHST AG

Inventor： ECKES PETER ,  PETER ECKES ,  WENGENMAYER FRIEDERICH ,  FRIEDERICH WENGENMAYER ,  DONN GUENTER ,  GUENTER DONN ,  SCHULZ ARNO ,  ARNO SCHULZ

IPC: C12N15/09 ,  A01H1/00 ,  A01H1/06 ,  A01H5/00 ,  C12N5/10 ,  C12N9/00 ,  C12N15/82 ,  A01H ,  C12N ,  C12P

公开(公告)号：ZA8803947B

公开(公告)日：1989-02-22

申请号：ZA8803947

申请日：1988-06-03

Applicant: HOECHST AG

Inventor： ECKES PETER ,  PETER ECKES ,  WENGENMAYER FRIEDERICH ,  FRIEDERICH WENGENMAYER ,  DONN GUENTER ,  GUENTER DONN ,  SCHULZ ARNO ,  ARNO SCHULZ

IPC: C12N15/09 ,  A01H1/00 ,  A01H1/06 ,  A01H5/00 ,  C12N5/10 ,  C12N9/00 ,  C12N15/82 ,  A01H ,  C12N ,  C12P

CPC classification number: C12N9/93 ,  A01H1/06 ,  C12N15/8261 ,  Y02A40/146

Abstract: Plants which overproduce glutamine synthetase have improved utilisation of nitrogen. They therefore thrive on soils which, because the supply of nitrogen which can be utilised by plants is too small, allow virtually no useful growth of the corresponding wild types.