2.
    发明专利
    未知

    公开(公告)号:DE3127239A1

    公开(公告)日:1983-01-20

    申请号:DE3127239

    申请日:1981-07-10

    Applicant: HOECHST AG

    Abstract: Quaternary N-alkyl-N,N'-,N'-polyoxyalkyl- alpha , omega -diamino-alkylene fatty acid esters of the formula (1) (1) in which R1 is C8-C30, preferably C16-C18-alkyl, or C8-C30, preferably C16-C18-alkenyl, R2 is C1-C4-alkyl, preferably methyl, R3 is C7-C29, preferably C15-C17-alkyl or C7-C29, preferably C15-C17-alkenyl, x and y each are hydrogen or methyl with the proviso that x and y are not simultaneously methyl, a is 0, 1 or 2, n is an integer of from 1 to 11, preferably 1, m is 1 or 2, p is an integer or from 1 to 5, preferably 3, and A is an anion, preferably a halogen, methosulfate or methophosphate ion. These compounds are prepared by esterifying the basis oxalkylated alkylene diamines with fatty acids and subsequent quaternization. They are used as softeners.

    Antibacterial quinoxaline-1,4-dioxides

    公开(公告)号:DE2002712A1

    公开(公告)日:1971-07-29

    申请号:DE2002712

    申请日:1970-01-22

    Applicant: HOECHST AG

    Abstract: Quinoxalinecarbohydrazone-1,4-dioxides have formula (I) (where R1 = 1-4C, R2 and R3 are indep. H, halogen, 1-6C alkyl or alkoxy, CF3, NH2 or NHAc, or R2+R3 = -OCH20-; aliphatic residue, 7-10C araliphatic residue or 3-7C cycloaliphatic residue opt. substd. by OH, alkoxy, NH2, NHalk, halogen, COOH, CONH2, CN or esters; R5-R4 or aromatic or opt. substd. heterocycle; R4+R5= opt. N- or O-containing and opt. substd. 4-7 membered ring. (I) are prepd. from the corresponding carbohydrazides and ketone.

    Amoebicidal 2-nitro-3-aminoalkylamino-pyridines - prepd by aminoalkylation of 2-nitro-3-amino-pyridine

    公开(公告)号:DE2334401A1

    公开(公告)日:1975-01-23

    申请号:DE2334401

    申请日:1973-07-06

    Applicant: HOECHST AG

    Abstract: 2-Nitro-3-aminoalkylamino-pyridines of formula (I): (where R1 and R2 are 1-4C alkyl or NR1R2 is pyrrolidino, piperidino, piperazino or morpholino opt. substd. by 1-3C alkyl, and X is di- or trimethylene opt. subst. by 1-3C alkyl) and their salts with physiologically tolerable acids (e.g. 2-nitro-3-(2-diisopropylaminoethylamino)-pyridine HCl) are new amoebicidal cpds. which are prepared by reacting Hal-X-NR1R2 (where Hal is halogen) with 2-nitro-3-aminopyridine (II) in the presence of a metal hydride or organometallic cpd. (e.g. C6H5Li, C4H9Li). (I) are amoebicides active against intestinal and extratestinal forms of amoebiasis, dosage 5-100 mg/kg orally or parenterally.

    Bacteriostatic 2-quinoxalinecarbohydrazide1,4-dioxides

    公开(公告)号:DE2002710A1

    公开(公告)日:1971-07-29

    申请号:DE2002710

    申请日:1970-01-22

    Applicant: HOECHST AG

    Abstract: Bacteriostatic 2-quinoxalinecarbohydrazide-1, 4-dioxides Title cpds. of formula (I) (where R1 = 1-4C alkyl esp. CH3;R2 = halogen esp. Cl or CF3;R3 and R4 are indep. H, 1-4C alkyl or hydroxyalkyl. (I) is prepd. via its reactive derivs., such as activated esters e.g. N-succinimide- or p-nitrophenyl-esters or mixed anhydrides or activated amides pref. imidazolides or pyrazolides. In an example 5.2 g 7-chloro-3-methyl-2-quinoxalinecarbohydrazide-1,4-dioxide was obtained from 12.7 g 7-chloro-3-methyl-2-quinoxalinecarboxylic acid-1, 4-dioxide, 5.75 g hydroxysuccinimide, 11.4 g dicyclohexylcarbodiimide and 4 g hydrazinehydrate.

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