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    5.
    发明专利
    未知

    公开(公告)号：DE3678657D1

    公开(公告)日：1991-05-16

    申请号：DE3678657

    申请日：1986-09-13

    Applicant: HOECHST AG

    Inventor： WINKELMANN ERHARDT DR ,  ROLLY HEINRICH DR ,  WINKLER IRVIN DR

    IPC: A61K31/52 ,  C07D473/00

    Abstract: Compounds of the formula 1 in which R is H, halogen, OH, SH, azido, NH2 or Z-R , where Z denotes O, S, SO, SO2 or NH and R denotes an acyclic aliphatic hydrocarbon radical having 1 to 6 C atoms, which a) is unsubstituted or b) is modified by at least one of the features that it contains an alkoxy group having 1 to 3 C atoms or a double bond or is at least partially fluorinated, or denotes cycloalkyl having 3 to 6 C atoms or phenylalkyl which is bonded directly to Z or via an alkylene group of 1 to 3 C atoms, or phenyl, where the phenyl ring can in each case be substituted at most twice, preferably at most once, by a substituent from the group halogen, trifluoromethyl, alkoxy and alkylthio each having 1 to 3 C atoms, R is H or has the meaning of R or is an acyl group CO-R , where R is alkyl having 1 to 6 C atoms, benzyl or phenyl, R denotes halogen, azido, unsubstituted amino or the radical Y-R , where R has the same meaning as R and Y, like X, denotes O, S, SO or SO2 and X and Y can be identical or different, where those compounds are excepted in which, at the same time, R is OH or SH, R is H, R is Y-R , X is O or S, Y is O and R is alkyl having 1 to 4 C atoms or in which, at the same time, R is OH or NH2, R is benzyl, R is Y-R where Y = O and R = benzyl and X is O, are used for the treatment of diseases caused by viruses.

    6.
    发明专利
    未知

    公开(公告)号：DE3627024A1

    公开(公告)日：1987-04-02

    申请号：DE3627024

    申请日：1986-08-09

    Applicant: HOECHST AG

    Inventor： WINKELMANN ERHARDT DR ,  ROLLY HEINRICH DR ,  WINKLER IRVIN DR

    IPC: A61K31/52 ,  C07D473/00 ,  C07D473/32

    Abstract: Compounds of the formula 1 in which R is H, halogen, OH, SH, azido, NH2 or Z-R , where Z denotes O, S, SO, SO2 or NH and R denotes an acyclic aliphatic hydrocarbon radical having 1 to 6 C atoms, which a) is unsubstituted or b) is modified by at least one of the features that it contains an alkoxy group having 1 to 3 C atoms or a double bond or is at least partially fluorinated, or denotes cycloalkyl having 3 to 6 C atoms or phenylalkyl which is bonded directly to Z or via an alkylene group of 1 to 3 C atoms, or phenyl, where the phenyl ring can in each case be substituted at most twice, preferably at most once, by a substituent from the group halogen, trifluoromethyl, alkoxy and alkylthio each having 1 to 3 C atoms, R is H or has the meaning of R or is an acyl group CO-R , where R is alkyl having 1 to 6 C atoms, benzyl or phenyl, R denotes halogen, azido, unsubstituted amino or the radical Y-R , where R has the same meaning as R and Y, like X, denotes O, S, SO or SO2 and X and Y can be identical or different, where those compounds are excepted in which, at the same time, R is OH or SH, R is H, R is Y-R , X is O or S, Y is O and R is alkyl having 1 to 4 C atoms or in which, at the same time, R is OH or NH2, R is benzyl, R is Y-R where Y = O and R = benzyl and X is O, are used for the treatment of diseases caused by viruses.

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