公开(公告)号：BR8007054A

公开(公告)日：1981-05-05

申请号：BR8007054

申请日：1980-10-31

Applicant: HOECHST AG

Inventor： SCHAEFFER G ,  SPIELMANN W

IPC: C07C69/614 ,  B01J23/00 ,  C07B61/00 ,  C07C51/00 ,  C07C51/377 ,  C07C57/32 ,  C07C57/58 ,  C07C59/52 ,  C07C59/64 ,  C07C67/00 ,  C07C69/73 ,  C07C69/76 ,  C07C227/00 ,  C07C227/16 ,  C07C229/42 ,  C07C231/00 ,  C07C231/12 ,  C07C235/42 ,  C07C51/347 ,  C07C53/134 ,  B01J23/44

Abstract: Phenylacetic acid and the simple derivatives thereof are prepared by catalytic hydrogenation of mandelic acid and its appropriate derivatives in the presence of a noble metal catalyst in aqueous solution which is free from mineral acid, especially free from hydrochloric acid.

公开(公告)号：BR7907679A

公开(公告)日：1980-07-22

申请号：BR7907679

申请日：1979-11-27

Applicant: HOECHST AG

Inventor： SPIELMANN W ,  SCHAEFFER G

IPC: C07C45/45 ,  C07C45/75 ,  C07C49/00 ,  C07C69/76 ,  C07D307/46 ,  C07D333/16 ,  C07D333/22 ,  C07C45/15

Abstract: Ketones are prepared by reacting carboxylic acid halides, in particular carboxylic acid chlorides, with aluminum-alkyl compounds, optionally in the presence of an aluminum trihalide, in methylene chloride as the solvent, at a temperature between about 20 DEG and about 100 DEG C., preferably between about 30 DEG and about 60 DEG C., more preferably of about 40 DEG C. which is the reflux temperature of the methylene chloride. When operating at a temperature above approximately 40 DEG C., pressure higher than atmospheric is applied. The reaction mixture is worked up in usual manner, suitably by decomposition with water followed by distillation.

公开(公告)号：BR8100243A

公开(公告)日：1981-08-04

申请号：BR8100243

申请日：1981-01-16

Applicant: HOECHST AG

Inventor： SCHAEFFER G ,  SPIELMANN W

IPC: C07C59/52 ,  C07C51/00 ,  C07C51/377 ,  C07C67/00 ,  C07C53/08

Abstract: p-Hydroxyphenylacetic acid is prepared by reduction of p-hydroxymandelic acid with HI in the presence of red phosphorus. According to a preferred embodiment, the reaction is carried out in one vessel in which the mandelic acid is prepared in situ from phenol and glyoxylic acid.

公开(公告)号：AU6627581A

公开(公告)日：1981-07-23

申请号：AU6627581

申请日：1981-01-16

Applicant: HOECHST AG

Inventor： SPIELMANN W ,  SCHAEFFER G

IPC: C07C59/52 ,  C07C51/00 ,  C07C51/377 ,  C07C67/00 ,  C07C59/48

Abstract: p-Hydroxyphenylacetic acid is prepared by reduction of p-hydroxymandelic acid with HI in the presence of red phosphorus. According to a preferred embodiment, the reaction is carried out in one vessel in which the mandelic acid is prepared in situ from phenol and glyoxylic acid.

公开(公告)号：AU6400380A

公开(公告)日：1981-05-07

申请号：AU6400380

申请日：1980-10-31

Applicant: HOECHST AG

Inventor： SPIELMANN W ,  SCHAEFFER G

IPC: C07C69/614 ,  B01J23/00 ,  C07B61/00 ,  C07C51/00 ,  C07C51/377 ,  C07C57/32 ,  C07C57/58 ,  C07C59/52 ,  C07C59/64 ,  C07C67/00 ,  C07C69/73 ,  C07C69/76 ,  C07C227/00 ,  C07C227/16 ,  C07C229/42 ,  C07C231/00 ,  C07C231/12 ,  C07C235/42 ,  C07C53/134 ,  C07C59/11

Abstract: Phenylacetic acid and the simple derivatives thereof are prepared by catalytic hydrogenation of mandelic acid and its appropriate derivatives in the presence of a noble metal catalyst in aqueous solution which is free from mineral acid, especially free from hydrochloric acid.