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    PROCESS FOR THE PREPARATION OF 5-SULFAMOYL-ANTHRANILIC ACIDS
    1.
    发明授权
    PROCESS FOR THE PREPARATION OF 5-SULFAMOYL-ANTHRANILIC ACIDS 失效

    公开(公告)号：KR800000746B1

    公开(公告)日：1980-08-02

    申请号：KR750000168

    申请日：1975-01-29

    Applicant: HOECHST AG

    Inventor： STURM K

    IPC: C07C143/78

    Abstract: Title compds. (I, Ph = halogen, alkyl, etheified hydroxyl group-substituted phenyl; R = aralkyl, heteroaralky1, cycloalkyl-alkyl), useful as diuretics, were prepd. by reacting carboxylic acids(IV) with > 1 mole eq. wt. amines(V)at >120≦̸C. 2,4-Dichloro-5-sulfamoyl benzonitrile(II) was used as a starting material for IV.

    PROCESS FOR PREPARING 5-SULFAMOYL-ORTHANILIC ACIDS
    2.
    发明授权
    PROCESS FOR PREPARING 5-SULFAMOYL-ORTHANILIC ACIDS 失效

    公开(公告)号：KR810001154B1

    公开(公告)日：1981-09-22

    申请号：KR780001255

    申请日：1978-04-26

    Applicant: HOECHST AG

    Inventor： STURM K ,  MUSCHAWECK R

    IPC: C07D307/06 ,  C07D333/06

    Abstract: 5-Sulfamoyl-orthanilic acids (I; R = cl, Br, methyl, phenoxy, phenylthio radical; Ar = furyl, thienyl radical; Z = H, metallic ion, ammounium ion, alkyline metallic ion; X = halogen; ph = substituted aromatic radical; Hal = halogen, Zl = H, metal, ammounium, ter-ammonium), having diuretic activity, were prepd. by reacting compd.(IV) with benzene sulfonic acid (V). The compd. (IV) was obtained from the reaction of compd. (II) and phenyl benzene sulfonate(III).

    7.
    发明专利
    未知

    公开(公告)号：SE7509897L

    公开(公告)日：1976-03-08

    申请号：SE7509897

    申请日：1975-09-05

    Applicant: HOECHST AG

    Inventor： STURM K ,  STAREY F

    IPC: C07D295/10 ,  C07D295/155 ,  C07D295/18

    Abstract: Antihypertensively-active 3-sulfamoyl-4-piperazinyl-benzoic acids, optionally substituted in the 2-position by halogen or alkyl, and the esters, amides, and nitriles of these acids are disclosed, as is a method for making these compounds by the reaction of the corresponding 4-halogeno- or 4-alkyl-(or 4-aryl-) sulfonyloxy-benzoic acids (or their esters etc.) with piperazines.

    8.
    发明专利
    未知

    公开(公告)号：DK399275A

    公开(公告)日：1976-03-07

    申请号：DK399275

    申请日：1975-09-05

    Applicant: HOECHST AG

    Inventor： STURM K ,  STAREY F

    IPC: C07D295/10 ,  C07D295/155 ,  C07D

    Abstract: Antihypertensively-active 3-sulfamoyl-4-piperazinyl-benzoic acids, optionally substituted in the 2-position by halogen or alkyl, and the esters, amides, and nitriles of these acids are disclosed, as is a method for making these compounds by the reaction of the corresponding 4-halogeno- or 4-alkyl-(or 4-aryl-) sulfonyloxy-benzoic acids (or their esters etc.) with piperazines.

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