公开(公告)号：JPS4924652B1

公开(公告)日：1974-06-25

申请号：JP3716570

申请日：1970-04-30

Applicant: HOFFMANN LA ROCHE

Inventor： CHODNEKAR M S ,  PFIFFNER A ,  RIGASSI N ,  SCHWIETER U ,  SUCHY M

IPC: A01N37/40 ,  A01N31/08 ,  A01N31/14 ,  A01N33/20 ,  A01N35/04 ,  A01N37/18 ,  A01N37/34 ,  A01N37/36 ,  A01N43/02 ,  A01N43/20 ,  A01N43/24 ,  A01N43/32 ,  A01N49/00 ,  C07C41/00 ,  C07C43/14 ,  C07C43/20 ,  C07C43/205 ,  C07C45/00 ,  C07C45/71 ,  C07C47/52 ,  C07C47/575 ,  C07C49/84 ,  C07C51/00 ,  C07C65/21 ,  C07C65/28 ,  C07C67/00 ,  C07C69/78 ,  C07C69/88 ,  C07C69/92 ,  C07C231/00 ,  C07C231/02 ,  C07C231/12 ,  C07C233/12 ,  C07C235/46 ,  C07C253/00 ,  C07C255/53 ,  C07C255/54 ,  C07C313/00 ,  C07C315/02 ,  C07C317/00 ,  C07C317/14 ,  C07C317/22 ,  C07C317/24 ,  C07C317/44 ,  C07C317/50 ,  C07C319/14 ,  C07C321/28 ,  C07C323/09 ,  C07C323/20 ,  C07C323/22 ,  C07C323/52 ,  C07C323/62 ,  C07C327/20 ,  C07D303/02 ,  C07D303/22 ,  C07D303/34 ,  C07D319/18 ,  C07D321/10 ,  C07D331/02 ,  C07D407/12

公开(公告)号：JPS4924215B1

公开(公告)日：1974-06-21

申请号：JP3716670

申请日：1970-04-30

Applicant: HOFFMANN LA ROCHE

Inventor： CHODNEKAR M S ,  PFIFFNER A ,  RIGASSI N ,  SCHWIETER U ,  SUCHY M

IPC: A01N37/40 ,  A01N31/08 ,  A01N31/14 ,  A01N33/20 ,  A01N35/04 ,  A01N37/18 ,  A01N37/34 ,  A01N37/36 ,  A01N43/02 ,  A01N43/20 ,  A01N43/24 ,  A01N43/32 ,  A01N49/00 ,  C07C41/00 ,  C07C43/14 ,  C07C43/20 ,  C07C43/205 ,  C07C45/00 ,  C07C45/71 ,  C07C47/52 ,  C07C47/575 ,  C07C49/84 ,  C07C51/00 ,  C07C65/21 ,  C07C65/28 ,  C07C67/00 ,  C07C69/78 ,  C07C69/88 ,  C07C69/92 ,  C07C231/00 ,  C07C231/02 ,  C07C231/12 ,  C07C233/12 ,  C07C235/46 ,  C07C253/00 ,  C07C255/53 ,  C07C255/54 ,  C07C313/00 ,  C07C315/02 ,  C07C317/00 ,  C07C317/14 ,  C07C317/22 ,  C07C317/24 ,  C07C317/44 ,  C07C317/50 ,  C07C319/14 ,  C07C321/28 ,  C07C323/09 ,  C07C323/20 ,  C07C323/22 ,  C07C323/52 ,  C07C323/62 ,  C07C327/20 ,  C07D303/02 ,  C07D303/22 ,  C07D303/34 ,  C07D319/18 ,  C07D321/10 ,  C07D331/02 ,  C07D407/12

公开(公告)号：US3742038A

公开(公告)日：1973-06-26

申请号：US3742038D

申请日：1971-01-14

Applicant: HOFFMANN LA ROCHE

Inventor： GUTMANN H ,  SCHWIETER U

IPC: A23L1/275 ,  A61K8/33 ,  A61K9/00 ,  A61K47/08 ,  A61Q1/02 ,  A61Q11/00 ,  C07C45/63 ,  C07C45/72 ,  C07C47/20 ,  C07C47/24 ,  C07F9/54 ,  C07C47/26 ,  C07C69/14

CPC classification number: A61Q11/00 ,  A23L5/47 ,  A61K8/33 ,  A61K9/0014 ,  A61K47/08 ,  A61K2800/43 ,  A61Q1/02 ,  C07C45/298 ,  C07C45/515 ,  C07C45/62 ,  C07C45/63 ,  C07C45/676 ,  C07C45/72 ,  C07C47/263 ,  C07F9/5442 ,  C07C47/277 ,  C07C47/24 ,  C07C47/21

Abstract: Conjugated polyene dialdehyde compounds having 14-44 carbon atoms and mixtures thereof which are useful as coloring agents for foodstuffs, pharmaceutical preparations and cosmetic preparations and a method for preparing these dialdehydes including various intermediates in this method. This method is carried out by reacting a phosphonium salt of a conjugated aliphatic olefine having a terminal aldehyde radical with a conjugated aliphatic olefine having a terminal acetal linkage radical and a terminal aldehyde radical and thereafter hydrolyzing the reaction product to produce the dialdehyde. This dialdehyde may be further chain lengthened by reacting this dialdehyde with a phosphonium salt of a conjugated olefine having a terminal aldehyde radical, or by reacting with a vinyl ether or propenyl ether.

Abstract translation: 具有14-44个碳原子的共轭多烯二醛化合物及其混合物，其可用作食品着色剂，药物制剂和化妆品制剂，以及在该方法中包括各种中间体的这些二醛的制备方法。 该方法通过使具有末端醛基的共轭脂族烯烃的鏻盐与具有末端缩醛连接基和末端醛基的共轭脂族烯烃反应，然后水解反应产物以产生二醛。 该二醛可以通过使该二醛与具有末端醛基的共轭烯烃的鏻盐反应或通过与乙烯基醚或丙烯基醚反应而进一步链延长。

公开(公告)号：US3781314A

公开(公告)日：1973-12-25

申请号：US3781314D

申请日：1971-07-14

Applicant: HOFFMANN LA ROCHE

Inventor： BOLLAG W ,  RIGASSI N ,  SCHWIETER U

IPC: C07C59/80 ,  C07C3/02

CPC classification number: C07C45/513 ,  C07C45/58 ,  C07C45/67 ,  C07C59/80 ,  C07F9/5352 ,  C07F9/5442 ,  C07C49/203 ,  C07C49/21

Abstract: THE COMPOUND 5,5-DIMETHYL-CYCLOPENT-1-ENE HAVING AN ACETYL, HYDROXY OR LOWER ALKYL GROUP IN THE 2-POSITION AND 3,7-DIMETHYL-NONA-2,4,6,8-TETRAENOIC ACID OR TETRAENOL DERIVATIVE IN THE 1-POSITION USEFUL AS ANTI-TUMORAGENTS AS WELL AS A METHOD FOR PREPARING THESE COMPOUNDS FROM VITAMIN A ACID DERIVATIVES.

公开(公告)号：US3769320A

公开(公告)日：1973-10-30

申请号：US3769320D

申请日：1970-04-20

Applicant: HOFFMANN LA ROCHE

Inventor： CHODNEKAR M ,  PFIFFNER A ,  SUCHY M ,  RIGASSI N ,  SCHWIETER U

IPC: A01N37/40 ,  A01N31/08 ,  A01N31/14 ,  A01N33/20 ,  A01N35/04 ,  A01N37/18 ,  A01N37/34 ,  A01N37/36 ,  A01N43/02 ,  A01N43/20 ,  A01N43/24 ,  A01N43/32 ,  A01N49/00 ,  C07C41/00 ,  C07C43/14 ,  C07C43/20 ,  C07C43/205 ,  C07C45/00 ,  C07C45/71 ,  C07C47/52 ,  C07C47/575 ,  C07C49/84 ,  C07C51/00 ,  C07C65/21 ,  C07C65/28 ,  C07C67/00 ,  C07C69/78 ,  C07C69/88 ,  C07C69/92 ,  C07C231/00 ,  C07C231/02 ,  C07C231/12 ,  C07C233/12 ,  C07C235/46 ,  C07C253/00 ,  C07C255/53 ,  C07C255/54 ,  C07C313/00 ,  C07C315/02 ,  C07C317/00 ,  C07C317/14 ,  C07C317/22 ,  C07C317/24 ,  C07C317/44 ,  C07C317/50 ,  C07C319/14 ,  C07C321/28 ,  C07C323/09 ,  C07C323/20 ,  C07C323/22 ,  C07C323/52 ,  C07C323/62 ,  C07C327/20 ,  C07D303/02 ,  C07D303/22 ,  C07D303/34 ,  C07D319/18 ,  C07D321/10 ,  C07D331/02 ,  C07D407/12

CPC classification number: C07C317/00 ,  C07C43/2055 ,  C07C45/71 ,  C07C47/575 ,  C07C49/84 ,  C07C65/28 ,  C07C317/14 ,  C07C317/44 ,  C07C321/28 ,  C07C323/52 ,  C07C323/62 ,  C07D319/18 ,  C07D321/10 ,  C07D331/02

Abstract: PHENYL ALKENYL ETHERS WHEREIN THE ALKENYL GROUP CONTAINS A CARBON CHAIN OF 8 OR 9 CARBON ATOMS AND THE TERMINAL UNSATURATED DOUBLE BOND CAN BE EPOXIDIZED OR EPISULFIDIZED, WHICH ARE USEFUL IN UPSETTING THE HORMONE BALANCE OF PESTS SUCH AS INSECTS.

公开(公告)号：US3712913A

公开(公告)日：1973-01-23

申请号：US3712970

申请日：1970-04-20

Applicant: HOFFMANN LA ROCHE

Inventor： CHODNEKAR M ,  PFIFFNER A ,  RIGASSI N ,  SCHWIETER U ,  SUCHY M

IPC: A01N37/40 ,  A01N31/08 ,  A01N31/14 ,  A01N33/20 ,  A01N35/04 ,  A01N37/18 ,  A01N37/34 ,  A01N37/36 ,  A01N43/02 ,  A01N43/20 ,  A01N43/24 ,  A01N43/32 ,  A01N49/00 ,  C07C41/00 ,  C07C43/14 ,  C07C43/20 ,  C07C43/205 ,  C07C45/00 ,  C07C45/71 ,  C07C47/52 ,  C07C47/575 ,  C07C49/84 ,  C07C51/00 ,  C07C65/21 ,  C07C65/28 ,  C07C67/00 ,  C07C69/78 ,  C07C69/88 ,  C07C69/92 ,  C07C231/00 ,  C07C231/02 ,  C07C231/12 ,  C07C233/12 ,  C07C235/46 ,  C07C253/00 ,  C07C255/53 ,  C07C255/54 ,  C07C313/00 ,  C07C315/02 ,  C07C317/00 ,  C07C317/14 ,  C07C317/22 ,  C07C317/24 ,  C07C317/44 ,  C07C317/50 ,  C07C319/14 ,  C07C321/28 ,  C07C323/09 ,  C07C323/20 ,  C07C323/22 ,  C07C323/52 ,  C07C323/62 ,  C07C327/20 ,  C07D303/02 ,  C07D303/22 ,  C07D303/34 ,  C07D319/18 ,  C07D321/10 ,  C07D331/02 ,  C07D407/12 ,  C07C149/40

CPC classification number: C07C317/00 ,  C07C43/2055 ,  C07C45/71 ,  C07C47/575 ,  C07C49/84 ,  C07C65/28 ,  C07C317/14 ,  C07C317/44 ,  C07C321/28 ,  C07C323/52 ,  C07C323/62 ,  C07D319/18 ,  C07D321/10 ,  C07D331/02

Abstract: ALKYL OR ALKENYL ETHERS OR THIOETHERS OF BENZENE OR BENZYL DERIVATIVES WHEREIN THE ALKYL OR ALKENYL RADICAL CONTAINS A CHAIN OF EIGHT OR NINE CARBON ATOMS, WHICH ARE USEFUL IN KILLING AND PREVENTING THE PROLIFERATION OF INSECTS BY UPSETTING THEIR HORMONE BALANCE.

Abstract translation: 苯氧基，苯基亚磺酰基，苯硫基，苯基磺酰基，苄氧基，苄硫基，苄基亚磺酰基或苄基磺酰基，烷基或烯基衍生物，其中烷基或链烯基含有至少7个碳原子，可用于通过破坏其激素平衡来杀死和防止昆虫的增殖。

公开(公告)号：US3839562A

公开(公告)日：1974-10-01

申请号：US12920271

申请日：1971-03-29

Applicant: HOFFMANN LA ROCHE

Inventor： CHODNEKAR M ,  SCHWIETER U ,  SUCHY M ,  PFIFFNER A ,  RIGASSI N

IPC: A01N49/00 ,  A01N53/00 ,  A01P7/04 ,  A01P23/00 ,  C07C15/44 ,  C07C29/147 ,  C07C51/09 ,  C07C51/363 ,  C07D303/22 ,  C07D303/32 ,  C07D303/42 ,  C07D317/54 ,  C07D317/64 ,  C07D319/18 ,  C07D319/20 ,  C07D321/10 ,  A01N9/08 ,  A01N9/28

CPC classification number: C07D303/22 ,  A01N53/00 ,  C07C15/44 ,  C07C29/147 ,  C07C51/09 ,  C07C51/363 ,  C07D303/32 ,  C07D303/42 ,  C07D317/54 ,  C07D317/64 ,  C07D319/18 ,  C07D319/20 ,  C07D321/10 ,  Y10S424/10 ,  Y10S424/12 ,  C07C57/03 ,  C07C57/52 ,  A01N2300/00 ,  C07C33/02

Abstract: 1. AN INSECTICIDE COMPOSITION USEFUL FOR COMBATTING APHIDS AND FLIES, COMPRISING AN INSECTICIDALLY EFFECTIVE AMOUNT OF BETWEEN 1 AND 10 PARTS BY WEIGHT OF A PYRETHRIN; AND AN AMOUNT, EFFECTIVE FOR ENHANCING THE INSECTICIDAL ACTIVITY OF SAID PYRETHRIN, OF BETWEEN 1 AND 10 PARTS BY WEIGHT OF A HORMONE-COMPOUND SELECTED FROM THE GROUP CONSISTING OF: 10,11-EPOXY-7-ETHYL-3,11-DIMETTHYL-TRIDECA-2,6-DIENOIC ACID MTHYL ESTER; 10,11-EPOXY-3-,7,11-TRIMETHYL-DODECA-2,6-DIENYL ETHYL ETHER; 10,11-EPOXY-3,7,11-TRIEMTHYL-DODECA-2,6-DIENOIC ACID ETHYL ESTER; 10,11-EPOXY-3,7,10,11-TETRAMETHYL-DODECA-2,6-DIENOIC ACID ETHYL ESTER; 10,11-EPOXY-3,7,11-TRIMETHYL-TRIDECA-2,6-DIENOIC ACID ETHYL ESTER; 6,7-EPOXY-3,7-DIMETHYL-TRIDECA-2,6-DIENOIC 10,11-EPOXY-7-ETHYL-3,7-DIMETHYL-TRIDECA-2,6-DIENOIC ACID ETHYL ESTER; (10,11-EPOXY-3,7,11-TRIMETHYL-2,6-DODECA-DIENYL)METHYLETHER; P-((4,5-EPOXY-1,5-DIMETHYLHEXYL)OXY)BENZOIC ACID METHYL ESTER; P((6,7-EPOXY-3,7-DIMETHYL-2-OCTENYL)OXY)BENZOIC ACID METHYL ESTER; 2-((2-PROPYNLOXY)METTHYL)-1,4-BENZODIOXANE; 6,7-EPOXY-3,7-DIMETHYL-2-OCTNENOIC ACID ALLYL ESTER; 1-((1,1-DIMETHYLALLYL)OXY)-6,7-EPOXY-3,7-DIMETHYL2-OCTENE; 6-(ALLYLOXY)-2,3-EPOXY-2-METHYLLHEPTANE; AND 1-(ALLYLOXY)-10,11-EPOXY-3,7,11-TRIMETHYL2,6-DODECADIENE.

公开(公告)号：US3812262A

公开(公告)日：1974-05-21

申请号：US23853372

申请日：1972-03-27

Applicant: HOFFMANN LA ROCHE

Inventor： CHODNEKAR M ,  THOMMEN H ,  SCHWIETER U

IPC: C07C45/29 ,  C07C49/835 ,  C07C49/84 ,  C07D317/54 ,  A01N9/24 ,  A01N9/28

CPC classification number: C07D317/54 ,  C07C45/298 ,  C07C49/794 ,  C07C49/80 ,  C07C49/807 ,  C07C49/84

Abstract: Compounds represented by the formula

ARE USED FOR COMBATTING PLANT FUNGI, NEMATODES AND INSECTS.

WHEREIN ONE OF R1 and R2 represents a member selected from the group consisting of hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy or propynyloxy and the other represents a member selected from the group consisting of halogen, hydroxy, lower alkyl, lower alkoxy or propynyloxy or R1 and R2 together represent a lower alkylenedioxy group, X is a member selected from the group consisting of

公开(公告)号：US3781309A

公开(公告)日：1973-12-25

申请号：US3781309D

申请日：1971-01-21

Applicant: HOFFMANN LA ROCHE

Inventor： SUBRAYA CHODNEKAR M ,  PFIFFNER A ,  SCHWIETER U ,  SUCHY M ,  RIGASSI N

IPC: C07D303/22 ,  C07D303/40 ,  C07D303/42 ,  C07D1/18

CPC classification number: C07D303/22 ,  C07D303/40 ,  C07D303/42 ,  Y10S424/12

Abstract: ALLYL ETHERS OR ESTERS OF ALIPHATIC ALCOHOLS OR ACIDS WHEREIN THE ALIPHATIC CHAIN CONTAINS AN EPOXIDE GROUP AND AT LEAST 7 CARBON ATOMS. THE ETHERS AND ESTERS ARE USEFUL IN KILLING AND PREVENTING THE PROLIFERATION OF INSECTS BY UPSETTING THEIR HORMONAL BALANCE.

公开(公告)号：US3840604A

公开(公告)日：1974-10-08

申请号：US23503772

申请日：1972-03-15

Applicant: HOFFMANN LA ROCHE

Inventor： CHODNEKAR M ,  SCHWIETER U ,  SUCHY M ,  PFIFFNER A ,  RIGASSI N

IPC: A01N31/00 ,  A01N43/30 ,  C07D317/54 ,  C07D317/64 ,  C07D319/18 ,  C07D321/10 ,  C07C43/20

CPC classification number: C07D321/10 ,  A01N31/00 ,  A01N43/30 ,  C07D317/54 ,  C07D317/64 ,  C07D319/18

Abstract: 1. A COMPOUND OF THE FORMULA:

1-(HC*C-CH2-O-C(-R3)(-R4)-),3-R1,4-R2-BENZENE

WHEREIN R1 IS HYDROGEN; R2 IS PROPYNLOXY; AND R3 AND R4 ARE HYDROGEN OR LOWER ALKYL.