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    ANALYTE SENSOR AND METHOD FOR MANUFACTURING AN ANALYTE SENSOR
    1.
    发明专利
    ANALYTE SENSOR AND METHOD FOR MANUFACTURING AN ANALYTE SENSOR 未知

    公开(公告)号：CA3241504A1

    公开(公告)日：2023-06-29

    申请号：CA3241504

    申请日：2022-12-06

    Applicant: HOFFMANN LA ROCHE

    Inventor： SLIOZBERG KIRILL ,  STECK ALEXANDER

    IPC: A61B5/1473 ,  A61B5/1486

    Abstract: The disclosure relates to an analyte sensor comprising a substrate, at least one working electrode, at least one second electrode and a membrane, wherein the membrane is located on top of the second electrode, and the second electrode has at least one first silver layer and at least one second silver layer which partially overlap with one another and have the same composition. The first and second silver layers intersect with one another to form a + or a T shape design. The sensor includes at least one exposed area of the first silver layer disposed on the exterior of the sensor to provide for direct contact with body fluid when implanted. The disclosure further relates to a process for manufacturing an analyte sensor.

    IMPLANTATION NEEDLE AND KIT
    2.
    发明专利
    IMPLANTATION NEEDLE AND KIT 未知

    公开(公告)号：SG11202103220VA

    公开(公告)日：2021-05-28

    申请号：SG11202103220V

    申请日：2019-10-23

    Applicant: HOFFMANN LA ROCHE

    Inventor： STECK ALEXANDER ,  HOCHMUTH GERNOT

    IPC: A61M37/00 ,  A61B5/145 ,  A61B17/00 ,  A61B17/34

    Abstract: An implantation needle has an implantable element receiving portion, a capsule receiving portion, and a tip portion. The capsule receiving portion has a fixing element such as a mechanical barrier or an adhesive surface. A kit is also provided that includes the implantation needle with an implantable element disposed in the implantable element receiving portion and a capsule disposed in the capsule receiving portion. The instant disclosure also relates to a method for administering an implantable element and a capsule to a subject. The method includes inserting an implantation needle of the implantation kit into a tissue of a subject and discharging the implantable element and capsule into the patient's tissue.

    Analyte sensor and a method for producing an analyte sensor
    5.
    发明专利
    Analyte sensor and a method for producing an analyte sensor 未知

    公开(公告)号：AU2021295539A1

    公开(公告)日：2022-09-29

    申请号：AU2021295539

    申请日：2021-06-21

    Applicant: HOFFMANN LA ROCHE

    Inventor： HOCHMUTH GERNOT ,  STECK ALEXANDER ,  SLIOZBERG KYRYLO

    IPC: A61B5/145 ,  A61B5/1486 ,  C12Q1/00 ,  G01N27/327

    Abstract: An analyte sensor (130) for determining an analyte concentration in a body fluid (132) and a method for producing the analyte sensor (130) are disclosed. The analyte sensor (130) comprises: − a substrate (134) having a first surface (136), the first surface (136) being configured to be faced towards the body fluid (132) comprising the analyte; − a working electrode (140); − an interferent electrode (142); and − at least one further electrode (144) selected from the group consisting of a counter electrode (146), a reference electrode and a counter/ reference electrode; wherein each of the working electrode (140) and the interferent electrode (142) comprises a layer (210) of a conductive material (212), wherein the working electrode (140) further comprises at least one enzyme, whereas the interferent electrode (142) is devoid of enzyme, and wherein the interferent electrode (142) and the working electrode (140) are electrically separated layers located adjacently on the first surface (136) of the substrate (134). The analyte sensor (130) allows a precise determination of the analyte concentration although interferents may be comprised by the body fluid (132).

    METHOD FOR AN ANALYTE SENSOR COVER-MEMBRANE PREPARATION
    6.
    发明专利
    METHOD FOR AN ANALYTE SENSOR COVER-MEMBRANE PREPARATION 未知

    公开(公告)号：CA3135019A1

    公开(公告)日：2020-11-12

    申请号：CA3135019

    申请日：2020-05-04

    Applicant: HOFFMANN LA ROCHE

    Inventor： HOCHMUTH GERNOT ,  HOERTZ CHRISTIAN ,  MISCHLER REINHOLD ,  SLIOZBERG KIRILL ,  STECK ALEXANDER ,  ZOU PENG

    IPC: A61B5/145 ,  C12Q1/00

    Abstract: The present invention relates to a process for forming a membrane on an analyte sensor. The present invention further relates to an analyte sensor obtainable by this process. Furthermore, the present invention relates to a process for forming a sensing layer on an electrode of an analyte sensor and to an analyte sensor comprising the sensing layer obtainable by the inventive process as well as the membrane obtainable by the inventive process. The analyte sensors obtainable by the inventive processes may mainly be used for conducting at least one analyte measurement of a bodily fluid of a user or a patient. The invention may both be applied in the field of home care as well as in the field of professional care, such as in hospitals. Other applications are generally feasible.

    9.
    发明专利
    未知

    公开(公告)号：ES2993498T3

    公开(公告)日：2025-01-02

    申请号：ES21193787

    申请日：2021-08-30

    Applicant: HOFFMANN LA ROCHE

    Inventor： STECK ALEXANDER

    IPC: A61B5/1473 ,  A61B5/1486

    Abstract: La presente invención se refiere a un sensor de analito que comprende un sustrato, al menos un primer electrodo, al menos un segundo electrodo y al menos una capa protectora que cubre al menos un segundo electrodo. La presente invención se refiere además a un procedimiento para fabricar el sensor de analito inventivo así como a un sistema de sensor de analito que comprende un sensor de analito según la presente invención y una unidad electrónica. El sensor de analito según la presente invención se puede utilizar principalmente para realizar mediciones de analito en un fluido corporal de un usuario. (Traducción automática con Google Translate, sin valor legal)

    Method and system for determining at least one membrane property of an analyte sensor
    10.
    发明专利
    Method and system for determining at least one membrane property of an analyte sensor 未知

    公开(公告)号：AU2021234062A1

    公开(公告)日：2022-09-08

    申请号：AU2021234062

    申请日：2021-03-08

    Applicant: HOFFMANN LA ROCHE

    Inventor： LAMBERTSON MICHAEL ,  SLIOZBERG KIRILL ,  STECK ALEXANDER ,  WEHOWSKI FREDERIC

    IPC: G01N27/327

    Abstract: A method for determining at least one membrane property of an analyte sensor (112) is disclosed. The analyte sensor (112) comprises at least two measurement electrodes (114). At least one of the measurement electrodes (114) comprises at least one membrane element (122) having the at least one membrane property. The method comprising the following steps: a) generating at least one fast-transient voltage signal and applying the fast-transient voltage signal to the measurement electrodes (114); b) measuring at least one response signal; c) determining the at least one membrane property by evaluating of the response signal.

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