公开(公告)号：WO2012103396A3

公开(公告)日：2012-11-08

申请号：PCT/US2012022821

申请日：2012-01-27

Applicant: HONEYWELL INT INC ,  WERNER CHRISTIAN ,  STEINBERG CHRISTOPH ,  MAURER JESSICA ,  ZUMAQUE HARRY

Inventor： WERNER CHRISTIAN ,  STEINBERG CHRISTOPH ,  MAURER JESSICA ,  ZUMAQUE HARRY

IPC: C01G19/02 ,  B01D37/02

CPC classification number: C01G19/02 ,  C01P2006/80

Abstract: Provided herein are methods for the preparation of high purity stannous oxide comprising: (a) reacting a Sn salt with a C2-12 dicarboxylic acid in the aqueous phase to form a suspension comprising a Sn-dicarboxylate complex; (b) washing the Sn-dicarboxylate complex with water to obtain a wash solution comprising a washed Sn-dicarboxylate complex essentially free of the anion of the Sn salt; and (c) reacting the washed Sn-dicarboxylate complex with a base to form high purity SnO, wherein the high purity SnO has an alpha radiation count of less than about 0.002 cph/cm2.

Abstract translation: 本文提供了制备高纯度氧化亚锡的方法，包括：（a）使Sn盐与C2-12二羧酸在水相中反应以形成包含Sn-二羧酸酯配合物的悬浮液; （b）用水洗涤所述Sn-二羧酸酯配合物以获得洗涤溶液，所述洗涤溶液包含基本上不含所述Sn盐的阴离子的洗涤过的Sn-二羧酸酯配合物; 和（c）将洗过的Sn-二羧酸盐配合物与碱反应以形成高纯度SnO，其中高纯SnO具有小于约0.002cph / cm2的α辐射计数。

公开(公告)号：WO2012103170A3

公开(公告)日：2012-11-01

申请号：PCT/US2012022484

申请日：2012-01-25

Applicant: HONEYWELL INT INC ,  WERNER CHRISTIAN ,  STEINBERG CHRISTOPH ,  GROTTI GIUSEPPE ,  JACKISCH BJOERN

Inventor： WERNER CHRISTIAN ,  STEINBERG CHRISTOPH ,  GROTTI GIUSEPPE ,  JACKISCH BJOERN

IPC: C07F7/22 ,  A61Q11/00

CPC classification number: C07F7/2244 ,  A61K8/19 ,  A61K8/365 ,  A61Q11/00 ,  C08G18/244

Abstract: The invention is drawn to a composition comprising a tin(II) 2-hydroxycarboxylate, where the 2-hydroxycarboxylate is preferably selected from the group consisting of glycolate, lactate, mandelate and 2-hydroxybutyrate. The tin(II) 2-hydroxycarboxylates may be prepared by a method comprising the steps of (a) providing an aqueous solution of a tin(II) salt, (b) adding a 2-hydroxycarboxylic acid, or a salt of a 2-hydroxycarboxylic acid, (c) further adding a base, wherein the tin(II) 2-hydroxycarboxylate precipitates, (d) optionally, isolating the tin(II) 2-hydroxycarboxylate, and (e) optionally, drying. The tin(II) 2-hydroxycarboxylates and compositions containing them are useful in oral care applications, and as catalysts for chemical condensation reactions and/or the production of polymers.

Abstract translation: 本发明涉及包含2-羟基羧酸锡（II）的组合物，其中2-羟基羧酸盐优选选自乙醇酸盐，乳酸盐，扁桃酸盐和2-羟基丁酸盐。 2-羟基羧酸锡（II）可以通过包括以下步骤的方法制备：（a）提供锡（II）盐的水溶液，（b）加入2-羟基羧酸或2-羟基羧酸的盐， 羟基羧酸，（c）进一步加入碱，其中2-羟基羧酸锡（II）沉淀，（d）任选分离2-羟基羧酸锡（II），和（e）任选地干燥。 2-羟基羧酸锡（II）和含有它们的组合物可用于口腔护理应用，以及用作化学缩合反应和/或聚合物生产的催化剂。

公开(公告)号：WO03072586B1

公开(公告)日：2004-05-13

申请号：PCT/US0305682

申请日：2003-02-24

Applicant: HONEYWELL INT INC

Inventor： WERNER CHRISTIAN ,  NERENZ FRANC ,  KANSCHIK-CONRADSEN ANDREAS

IPC: C12N15/09 ,  C07B61/00 ,  C07H19/073 ,  C07H19/10 ,  C07H19/173 ,  C07H19/20 ,  C07B47/00 ,  C07F9/24 ,  C07H21/00

CPC classification number: C07H19/10 ,  C07H19/20

Abstract: Provided are methods of producing phosphitylated compounds, including 3'-O­phosphoramidites, comprising the step of reacting a hydroxyl-containing compound with a phosphitylating agent in the presence of a phosphitylation activator selected from the group consisting of (1) acid-base complexes derived from an amine base of Formula (I) wherein R, R , and R are independently C1-C10 alkyl, C1-C10 cycloalkyl, C1-Cl0 aryl, Cl-C10 aralkyl, Cl-C10 heteroalkyl, or Cl-CIO heteroaryl; (2) acid-base complexes derived from an amine base of Formula (II) wherein R , R , R , R , and are independently hydrogen, C1-C10 alkyl, Cl-C10 cycloalkyl, Cl-C10 aryl, Cl-CIO aralkyl, Cl-CIO heteroalkyl, or C1-C10 heteroaryl, and at least one of R , R , R , R , and R is not hydrogen.; (3) acid-base complexes derived from a diazabicyclo amine base; (4) zwitterionic amine complexes; and (5) combinations of two or more thereof, to produce a phosphitylated compound.

Abstract translation: 提供了包括3'-O-亚磷酰胺在内的亚磷酸化合物的制备方法，该方法包括在选自以下的亚磷酸化活化剂存在下使含羟基化合物与亚磷酸化剂反应的步骤：（1）衍生自 （I）的胺碱，其中R，R 1和R 2独立地为C 1 -C 10烷基，C 1 -C 10环烷基，C 1 -C 10芳基，C 1 -C 10芳烷基，C 1 -C 10杂烷基或Cl -ClO杂芳基; （2）衍生自其中R 3，R 4，R 5，R 6和R 6独立地为氢，C 1 -C 10烷基，C 1 -C 10烷氧基， C10环烷基，C1-C10芳基，C1-C10芳烷基，C1-C10杂烷基或C1-C10杂芳基，以及R 3，R 4，R 5，R 6和 R 7不是氢。 （3）衍生自二氮杂双环胺碱的酸 - 碱络合物; （4）两性离子胺络合物; 和（5）其两种或更多种的组合以产生亚磷酸化化合物。

公开(公告)号：EP2668136A4

公开(公告)日：2016-07-06

申请号：EP12739986

申请日：2012-01-27

Applicant: HONEYWELL INT INC ,  WERNER CHRISTIAN ,  STEINBERG CHRISTOPH ,  MAURER JESSICA

Inventor： WERNER CHRISTIAN ,  STEINBERG CHRISTOPH ,  MAURER JESSICA ,  ZUMAQUE HARRY

IPC: C01G19/02 ,  B01D37/02

CPC classification number: C01G19/02 ,  C01P2006/80

Abstract: Provided herein are methods for the preparation of high purity stannous oxide comprising: (a) reacting a Sn salt with a C2-12 dicarboxylic acid in the aqueous phase to form a suspension comprising a Sn-dicarboxylate complex; (b) washing the Sn-dicarboxylate complex with water to obtain a wash solution comprising a washed Sn-dicarboxylate complex essentially free of the anion of the Sn salt; and (c) reacting the washed Sn-dicarboxylate complex with a base to form high purity SnO, wherein the high purity SnO has an alpha radiation count of less than about 0.002 cph/cm2.

Abstract translation: 本文提供了制备高纯度氧化亚锡的方法，包括：（a）在水相中使Sn盐与C 2-12二羧酸反应以形成包含Sn-二羧酸络合物的悬浮液; （b）用水洗涤所述Sn-二羧酸络合物，得到包含基本上不含Sn盐的阴离子的经洗涤的Sn-二羧酸盐络合物的洗涤溶液; 和（c）使经洗涤的Sn-二羧酸酯配合物与碱反应以形成高纯度SnO，其中高纯度SnO具有小于约0.002cph / cm 2的α辐射计数。

公开(公告)号：CA2594538A1

公开(公告)日：2006-07-20

申请号：CA2594538

申请日：2005-12-22

Applicant: HONEYWELL INT INC

Inventor： KELLERMEIER BERND ,  GENNBURG WOLFGANG ,  HOYER SUSANNE ,  WERNER CHRISTIAN ,  KANSCHIK-CONRADSEN ANDREAS

IPC: C08G61/12

Abstract: Conductive polymers and a method of forming conductive polymers. More particularly, a method of forming head-to-tail coupled regioregular poly-(3-substituted) thiophenes having improved charge carrier mobility and current modulation. Also, monomers having two different halogen leaving groups and which form regioregular poly-(3-substituted) thiophenes more efficiently and economically than other processes. Polythiophene polymers, films and articles are also provided.

公开(公告)号：AU2003217706A1

公开(公告)日：2003-09-09

申请号：AU2003217706

申请日：2003-02-24

Applicant: HONEYWELL INT INC

Inventor： WERNER CHRISTIAN ,  NERENZ FRANC ,  KANSCHIK-CONRADSEN ANDREAS

IPC: C12N15/09 ,  C07B61/00 ,  C07H19/073 ,  C07H19/10 ,  C07H19/173 ,  C07H19/20

Abstract: Provided are methods of producing phosphitylated compounds, including 3'-O-phosphoramidites, comprising the step of reacting a hydroxyl-containing compound with a phosphitylating agent in the presence of a phosphitylation activator selected from the group consisting of: (1) acid-base complexes derived from an amine base of Formula II wherein R 3 , R 4 , R 5 , R 6 , and R 7 are independently hydrogen, C 1 -C 10 alkyl, C 3 -C 10 cycloalkyl, C 6 -C 10 aryl, C 7 -C 10 aralkyl, C 1 -C 10 heteroalkyl, or C 1 -C 10 heteroaryl, and at least one of R 3 , R 4 , R 5 , R 6 , and R 7 is not hydrogen; (2) zwitterionic amine complexes; and (3) combinations of two or more thereof, to produce a phosphitylated compound. Further provided are methods for purifying phosphitylated compounds comprising the steps of providing a phosphitylated compound in a solution solvent, contacting said phosphitylated compound with a precipitation solvent, and precipitating said phosphitylated compound.

公开(公告)号：DK2668136T3

公开(公告)日：2018-07-23

申请号：DK12739986

申请日：2012-01-27

Applicant: HONEYWELL INT INC ,  WERNER CHRISTIAN ,  STEINBERG CHRISTOPH ,  MAURER JESSICA

Inventor： WERNER CHRISTIAN ,  STEINBERG CHRISTOPH ,  MAURER JESSICA ,  ZUMAQUE HARRY

IPC: C01G19/02 ,  B01D37/02

公开(公告)号：CA2477039A1

公开(公告)日：2003-09-04

申请号：CA2477039

申请日：2003-02-24

Applicant: HONEYWELL INT INC

Inventor： KANSCHIK-CONRADSEN ANDREAS ,  NERENZ FRANC ,  WERNER CHRISTIAN

IPC: C12N15/09 ,  C07B61/00 ,  C07H19/073 ,  C07H19/10 ,  C07H19/173 ,  C07H19/20 ,  C07B47/00 ,  C07H21/00 ,  C07F9/24

Abstract: Provided are methods of producing phosphitylated compounds, including 3'- O~phosphoramidites, comprising the step of reacting a hydroxyl-containing compound with a phosphitylating agent in the presence of a phosphitylation activator selected from the group consisting of (1) acid-base complexes derived from an amine base of Formula (I) wherein R, R1, and R2 are independently C1-C10 alkyl, C1-C10 cycloalkyl, C1-Cl0 aryl, Cl-C10 aralkyl, Cl- C10 heteroalkyl, or Cl-CIO heteroaryl; (2) acid-base complexes derived from an amine base of Formula (II) wherein R3, R4, R5, R6, and are independently hydrogen, C1-C10 alkyl, Cl-C10 cycloalkyl, Cl-C10 aryl, Cl-CIO aralkyl, Cl-C IO heteroalkyl, or C1-C10 heteroaryl, and at least one of R3, R4, R5, R6, and R 7 is not hydrogen.; (3) acid-base complexes derived from a diazabicyclo amine base; (4) zwitterionic amine complexes; and (5) combinations of two or more thereof, to produce a phosphitylated compound.

公开(公告)号：ES2675933T3

公开(公告)日：2018-07-13

申请号：ES12739986

申请日：2012-01-27

Applicant: HONEYWELL INT INC ,  WERNER CHRISTIAN ,  STEINBERG CHRISTOPH ,  MAURER JESSICA

Inventor： WERNER CHRISTIAN ,  STEINBERG CHRISTOPH ,  MAURER JESSICA ,  ZUMAQUE HARRY

IPC: C01G19/02 ,  B01D37/02

Abstract: Un método para la preparación de SnO que comprende: (a) hacer reaccionar una sal de estaño con un ácido dicarboxílico C2-12 en fase acuosa para formar una suspensión que comprende un complejo de dicarboxilato de estaño; (b) lavar el complejo de dicarboxilato de estaño con agua para obtener una disolución de lavado y un complejo de dicarboxilato de estaño lavado en donde una concentración del anión de la sal de estaño en el complejo de dicarboxilato de estaño lavado es menor que un 1 % en peso, en donde el lavado del complejo de dicarboxilato de estaño continúa hasta que la disolución de lavado presenta un pH neutro y (c) hacer reaccionar el complejo de dicarboxilato de estaño lavado con una base para formar SnO, en donde el SnO presenta un recuento de radiación alfa menor que 0.002 cph/cm2 y en donde el SnO presenta una pureza de al menos un 99 % en peso, excluyendo cualquier SnO2 presente.

公开(公告)号：DE602005007387D1

公开(公告)日：2008-07-17

申请号：DE602005007387

申请日：2005-12-22

Applicant: HONEYWELL INT INC

Inventor： WERNER CHRISTIAN ,  KANSCHIK-CONRADSEN ANDREAS ,  FRAUKE PLATZ

IPC: C07D333/06

Abstract: A method for the formation of 3-alkylthiophenes or 3-arylthiophenes from 3-halothiophenes. More particularly, improvements on the Kumada coupling reaction for the production of 3-alkylthiophenes or 3-arylthiophenes by reacting a 3-halothiophene with an alkylmagnesiumhalide or arylmagnesiumhalide Grignard reagent in the presence of a catalyst and a 2-methyl tetrahydrofuran solvent. The 2-methyl tetrahydrofuran solvent allows for higher concentrations of the Grignard reagent with minimal or no dithienyl side product generation, achieving higher product yields and at a lower cost than other known methods.